CA3053218A1 - High-fidelity cas9 variants and applications thereof - Google Patents
High-fidelity cas9 variants and applications thereof Download PDFInfo
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- CA3053218A1 CA3053218A1 CA3053218A CA3053218A CA3053218A1 CA 3053218 A1 CA3053218 A1 CA 3053218A1 CA 3053218 A CA3053218 A CA 3053218A CA 3053218 A CA3053218 A CA 3053218A CA 3053218 A1 CA3053218 A1 CA 3053218A1
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| JP6261500B2 (ja) | 2011-07-22 | 2018-01-17 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ヌクレアーゼ切断特異性の評価および改善 |
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| US11214779B2 (en) * | 2015-04-08 | 2022-01-04 | University of Pittsburgh—of the Commonwealth System of Higher Education | Activatable CRISPR/CAS9 for spatial and temporal control of genome editing |
| KR102840885B1 (ko) * | 2015-06-18 | 2025-07-30 | 더 브로드 인스티튜트, 인코퍼레이티드 | 표적외 효과를 감소시키는 crispr 효소 돌연변이 |
| US9512446B1 (en) * | 2015-08-28 | 2016-12-06 | The General Hospital Corporation | Engineered CRISPR-Cas9 nucleases |
| IT201700016321A1 (it) | 2017-02-14 | 2018-08-14 | Univ Degli Studi Di Trento | Mutanti di cas9 ad alta specificita' e loro applicazioni. |
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| EP3583209B8 (en) | 2025-02-26 |
| EA037825B1 (ru) | 2021-05-25 |
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