CA3045665A1 - Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells - Google Patents
Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells Download PDFInfo
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- CA3045665A1 CA3045665A1 CA3045665A CA3045665A CA3045665A1 CA 3045665 A1 CA3045665 A1 CA 3045665A1 CA 3045665 A CA3045665 A CA 3045665A CA 3045665 A CA3045665 A CA 3045665A CA 3045665 A1 CA3045665 A1 CA 3045665A1
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Classifications
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| ES2671004T3 (es) | 2013-03-07 | 2018-06-04 | Baylor College Of Medicine | Dirección a CD138 en cáncer |
| TWI654206B (zh) | 2013-03-16 | 2019-03-21 | 諾華公司 | 使用人類化抗－ｃｄ１９嵌合抗原受體治療癌症 |
| RU2717984C2 (ru) | 2013-11-21 | 2020-03-27 | ЮСиЭл БИЗНЕС ЛТД | Клетка |
| WO2015092024A2 (en) | 2013-12-20 | 2015-06-25 | Cellectis | Method of engineering multi-input signal sensitive t cell for immunotherapy |
| EP3626748A1 (en) | 2014-01-13 | 2020-03-25 | Stephen J. Forman | Chimeric antigen receptors (cars) having mutations in the fc spacer region and methods for their use |
| WO2015142675A2 (en) | 2014-03-15 | 2015-09-24 | Novartis Ag | Treatment of cancer using chimeric antigen receptor |
| RU2016143389A (ru) | 2014-04-10 | 2018-05-15 | Сиэтл Чилдрен'С Хоспитал (Дба Сиэтл Чилдрен'С Ресёрч Инститьют) | Получение генно-инженерных т-клеток посредством транспозона "спящая красавица" в сочетании с отбором метотрексатом |
| MX2018001568A (es) | 2015-08-07 | 2019-04-25 | Seattle Children´S Hospital Dba Seattle Children´S Res Institute | Celulas t biespecificas de receptor quimerico de antigeno (car) para focalizacion a tumores solidos. |
| EP3411393B1 (en) | 2016-02-05 | 2021-04-07 | City of Hope | Administration of engineered t cells for treatment of cancers in the central nervous system |
| MX2019006631A (es) | 2016-12-12 | 2019-11-12 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Variantes quimericas de factores de transcripcion con sensibilidad aumentada a induccion por ligando de farmaco de expresion transgenica en celulas mamiferas. |
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2017
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- 2017-12-11 CN CN201780086283.8A patent/CN110291200B/zh active Active
- 2017-12-11 US US16/467,015 patent/US11408005B2/en active Active
- 2017-12-11 EP EP17881828.2A patent/EP3551197B1/en active Active
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- 2017-12-11 AU AU2017375630A patent/AU2017375630B2/en active Active
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| EP3551197A4 (en) | 2020-10-28 |
| WO2018111763A9 (en) | 2018-07-19 |
| EP3551197B1 (en) | 2023-11-22 |
| US20220411805A1 (en) | 2022-12-29 |
| JP7091357B2 (ja) | 2022-06-27 |
| US11408005B2 (en) | 2022-08-09 |
| JP2022130485A (ja) | 2022-09-06 |
| WO2018111763A1 (en) | 2018-06-21 |
| CN110291200B (zh) | 2024-05-14 |
| JP7392043B2 (ja) | 2023-12-05 |
| CN110291200A (zh) | 2019-09-27 |
| US20200181624A1 (en) | 2020-06-11 |
| MX2019006631A (es) | 2019-11-12 |
| JP2020500563A (ja) | 2020-01-16 |
| EP3551197A1 (en) | 2019-10-16 |
| AU2017375630A1 (en) | 2019-06-13 |
| AU2017375630B2 (en) | 2023-12-21 |
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