CA3044949A1 - Medical use of interferon-lambda for the treatment of fibrosis - Google Patents
Medical use of interferon-lambda for the treatment of fibrosis Download PDFInfo
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- CA3044949A1 CA3044949A1 CA3044949A CA3044949A CA3044949A1 CA 3044949 A1 CA3044949 A1 CA 3044949A1 CA 3044949 A CA3044949 A CA 3044949A CA 3044949 A CA3044949 A CA 3044949A CA 3044949 A1 CA3044949 A1 CA 3044949A1
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- lambda
- fibrosis
- interferon
- ifn
- functional mimetic
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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Landscapes
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- Life Sciences & Earth Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| GB1621728.3 | 2016-12-20 | ||
| GBGB1621728.3A GB201621728D0 (en) | 2016-12-20 | 2016-12-20 | Methods |
| PCT/EP2017/083949 WO2018115199A1 (en) | 2016-12-20 | 2017-12-20 | Medical use of interferon-lambda for the treatment of fibrosis |
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| CA3044949A1 true CA3044949A1 (en) | 2018-06-28 |
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|---|---|---|---|
| CA3044949A Abandoned CA3044949A1 (en) | 2016-12-20 | 2017-12-20 | Medical use of interferon-lambda for the treatment of fibrosis |
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| EP (1) | EP3558342B1 (https=) |
| JP (3) | JP7609556B2 (https=) |
| CN (1) | CN110381985A (https=) |
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| BR (1) | BR112019012084A2 (https=) |
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| GB (1) | GB201621728D0 (https=) |
| TW (1) | TW201828973A (https=) |
| UY (1) | UY37534A (https=) |
| WO (1) | WO2018115199A1 (https=) |
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| JP7674628B2 (ja) | 2016-02-19 | 2025-05-12 | イーアイティー・ファーマ・インコーポレイテッド | インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置 |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| EP3375452B1 (en) * | 2017-03-16 | 2025-01-08 | Evangelos Andreakos | Use of lambda interferons in the treatment of an obesity-related disorder, atherosclerosis or a coagulation disorder |
| EP3849592A4 (en) * | 2018-08-23 | 2022-08-24 | Exalt Therapeutics, LLC | MODIFIED IFNL3 POLYPEPTIDES COMPRISING A PHARMACOKINETIC ENHANCING FRAGMENT AND THEIR USES |
| EP3999101A1 (en) * | 2019-07-18 | 2022-05-25 | ENYO Pharma | Method for decreasing adverse-effects of interferon |
| CN110882381B (zh) * | 2019-12-18 | 2020-11-17 | 中国人民解放军陆军军医大学第一附属医院 | 重组IFN-λ1蛋白在制备防治炎症性骨丢失药物中的应用 |
| WO2021119749A1 (en) * | 2019-12-20 | 2021-06-24 | The Council Of The Queensland Institute Of Medical Research | Treatment of gastrointestinal disease |
| CN114736878B (zh) * | 2021-01-07 | 2024-04-19 | 秦皇岛摩登狗生物科技有限公司 | 共表达猪干扰素l3和猪白介素22重组杆状病毒及应用 |
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| GB9113120D0 (en) | 1991-06-18 | 1991-08-07 | Kodak Ltd | Photographic processing apparatus |
| MXPA03009082A (es) | 2001-04-06 | 2004-11-22 | Maxygen Holdings Ltd | Variantes polipeptidicas de interferon gamma. |
| EP1551369A4 (en) | 2002-08-28 | 2007-05-09 | Intermune Inc | COMBINATION THERAPY FOR THE TREATMENT OF FIBROTIC DISEASES |
| AU2003225670A1 (en) | 2003-02-28 | 2004-09-28 | Intermune, Inc. | Interferon drug therapy for the treatment of viral diseases and liver fibrosis |
| AU2003299962A1 (en) | 2003-02-28 | 2004-09-28 | Intermune, Inc. | Interferon drug therapy for the treatment of viral diseases and liver fibrosis |
| WO2004105684A2 (en) | 2003-05-16 | 2004-12-09 | Intermune, Inc. | Combination therapy for proliferative disorders |
| GB0315457D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| ES2551439T5 (es) | 2003-07-01 | 2018-11-08 | Ucb Biopharma Sprl | Fragmentos Fab de anticuerpos modificados |
| GB0315450D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| US20070258946A1 (en) * | 2003-12-23 | 2007-11-08 | Blatt Lawrence M | Combination Therapy for Treating Hepatitis C Virus Infection |
| WO2005110478A2 (en) | 2004-04-13 | 2005-11-24 | Intermune, Inc. | Combination therapy for treating fibrotic disorders |
| GB0411186D0 (en) | 2004-05-19 | 2004-06-23 | Celltech R&D Ltd | Biological products |
| US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| EP1991679A2 (fr) | 2006-03-08 | 2008-11-19 | Biomethodes | Variants de l'interferon- gamma humain (ifngamma) |
| EP2535349A1 (en) | 2007-09-26 | 2012-12-19 | UCB Pharma S.A. | Dual specificity antibody fusions |
| AU2009255994B2 (en) * | 2008-06-05 | 2014-07-17 | Bristol-Myers Squibb Company | Use of pegylated Type III Interferons for the treatment of hepatitis C |
| US20110263484A1 (en) | 2008-10-13 | 2011-10-27 | Zymogenetics, Inc. | Single chain fc type iii interferons and methods of using same |
| WO2010048468A1 (en) | 2008-10-23 | 2010-04-29 | Concert Pharmaceuticals, Inc. | Deuterated macrocyclic inhibitors of viral ns3 protease |
| EP2350124A1 (en) * | 2008-11-20 | 2011-08-03 | Zymogenetics, Inc. | Il-29 mutants and uses thereof |
| WO2011075605A2 (en) * | 2009-12-18 | 2011-06-23 | Alios Biopharma, Inc. | Hyperglycosylated interferon variants and methods of use |
| IT1400236B1 (it) | 2010-05-10 | 2013-05-24 | Univ Bari | Impiego di composti noti per il trattamento dell'insufficienza renale cronica(irc) |
| CN102584979B (zh) * | 2011-01-18 | 2015-10-14 | 北京凯因科技股份有限公司 | PEG化干扰素λ |
| US9678074B2 (en) | 2012-03-28 | 2017-06-13 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Interferon-λ4 (IFNL4) protein, related nucleic acid molecules, and uses thereof |
| JP7674628B2 (ja) | 2016-02-19 | 2025-05-12 | イーアイティー・ファーマ・インコーポレイテッド | インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置 |
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- 2017-12-20 UY UY0001037534A patent/UY37534A/es not_active Application Discontinuation
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Also Published As
| Publication number | Publication date |
|---|---|
| JP7609556B2 (ja) | 2025-01-07 |
| GB201621728D0 (en) | 2017-02-01 |
| JP2024156844A (ja) | 2024-11-06 |
| WO2018115199A1 (en) | 2018-06-28 |
| EP3558342B1 (en) | 2025-01-29 |
| US20190374610A1 (en) | 2019-12-12 |
| BR112019012084A2 (pt) | 2019-11-12 |
| US11975046B2 (en) | 2024-05-07 |
| UY37534A (es) | 2018-09-28 |
| EA201991175A1 (ru) | 2019-11-29 |
| TW201828973A (zh) | 2018-08-16 |
| EP3558342A1 (en) | 2019-10-30 |
| JP2022081677A (ja) | 2022-05-31 |
| US20240000893A1 (en) | 2024-01-04 |
| AR110404A1 (es) | 2019-03-27 |
| CN110381985A (zh) | 2019-10-25 |
| JP2020511415A (ja) | 2020-04-16 |
| ES3019566T3 (en) | 2025-05-20 |
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| Date | Code | Title | Description |
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Effective date: 20240402 |