CA3042391A1 - Methods of nucleic acid sample preparation for immune repertoire sequencing - Google Patents
Methods of nucleic acid sample preparation for immune repertoire sequencing Download PDFInfo
- Publication number
- CA3042391A1 CA3042391A1 CA3042391A CA3042391A CA3042391A1 CA 3042391 A1 CA3042391 A1 CA 3042391A1 CA 3042391 A CA3042391 A CA 3042391A CA 3042391 A CA3042391 A CA 3042391A CA 3042391 A1 CA3042391 A1 CA 3042391A1
- Authority
- CA
- Canada
- Prior art keywords
- nucleic acid
- primer
- target
- adapter
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662416677P | 2016-11-02 | 2016-11-02 | |
| US62/416,677 | 2016-11-02 | ||
| PCT/US2017/059804 WO2018085599A2 (en) | 2016-11-02 | 2017-11-02 | Methods of nucleic acid sample preparation for immune repertoire sequencing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3042391A1 true CA3042391A1 (en) | 2018-05-11 |
Family
ID=62077010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3042391A Pending CA3042391A1 (en) | 2016-11-02 | 2017-11-02 | Methods of nucleic acid sample preparation for immune repertoire sequencing |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10947582B2 (OSRAM) |
| EP (2) | EP4198140B1 (OSRAM) |
| JP (2) | JP7161991B2 (OSRAM) |
| CN (1) | CN110191959B (OSRAM) |
| AU (2) | AU2017355460B2 (OSRAM) |
| CA (1) | CA3042391A1 (OSRAM) |
| ES (1) | ES2940620T3 (OSRAM) |
| WO (1) | WO2018085599A2 (OSRAM) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2905448T3 (es) | 2012-05-10 | 2022-04-08 | Massachusetts Gen Hospital | Métodos para determinar una secuencia nucleotídica |
| JP6338221B2 (ja) * | 2012-10-24 | 2018-06-06 | タカラ バイオ ユーエスエー， インコーポレイテッド | 核酸生成物を生成するための、テンプレートスイッチに基づく方法 |
| WO2015112974A1 (en) | 2014-01-27 | 2015-07-30 | The General Hospital Corporation | Methods of preparing nucleic acids for sequencing |
| HK1250245A1 (zh) | 2015-04-10 | 2018-12-07 | Spatial Transcriptomics Ab | 生物样本的空间区别、多重核酸分析 |
| EP4353830A3 (en) | 2016-09-15 | 2024-07-03 | ArcherDX, LLC | Methods of nucleic acid sample preparation for analysis of cell-free dna |
| US20220282305A1 (en) * | 2016-09-15 | 2022-09-08 | Archerdx, Llc | Methods of nucleic acid sample preparation |
| JP6997772B2 (ja) | 2016-09-15 | 2022-01-18 | アーチャーディーエックス， エルエルシー | 核酸サンプル調製の方法 |
| CN110191959B (zh) * | 2016-11-02 | 2024-04-09 | 阿谢尔德克斯有限责任公司 | 用于免疫组库测序的核酸样品制备方法 |
| US12188014B1 (en) * | 2018-07-25 | 2025-01-07 | 10X Genomics, Inc. | Compositions and methods for nucleic acid processing using blocking agents |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| WO2020123318A1 (en) | 2018-12-10 | 2020-06-18 | 10X Genomics, Inc. | Resolving spatial arrays using deconvolution |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| JP7441243B2 (ja) * | 2019-05-14 | 2024-02-29 | エフ． ホフマン－ラ ロシュ アーゲー | 試料分析のための装置および方法 |
| EP3976820A1 (en) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| CN111139286B (zh) * | 2019-11-07 | 2023-11-21 | 南方医科大学南方医院 | 一种bcr高通量测序文库的构建方法 |
| WO2021092433A2 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
| EP4081656A1 (en) | 2019-12-23 | 2022-11-02 | 10X Genomics, Inc. | Compositions and methods for using fixed biological samples in partition-based assays |
| ES2982420T3 (es) | 2019-12-23 | 2024-10-16 | 10X Genomics Inc | Métodos para el análisis espacial mediante el uso de la ligazón con plantilla de ARN |
| US12365942B2 (en) | 2020-01-13 | 2025-07-22 | 10X Genomics, Inc. | Methods of decreasing background on a spatial array |
| US12405264B2 (en) | 2020-01-17 | 2025-09-02 | 10X Genomics, Inc. | Electrophoretic system and method for analyte capture |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
| US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| WO2021158925A1 (en) | 2020-02-07 | 2021-08-12 | 10X Genomics, Inc. | Quantitative and automated permeabilization performance evaluation for spatial transcriptomics |
| US12281357B1 (en) | 2020-02-14 | 2025-04-22 | 10X Genomics, Inc. | In situ spatial barcoding |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| ES2965354T3 (es) | 2020-04-22 | 2024-04-12 | 10X Genomics Inc | Métodos para análisis espacial que usan eliminación de ARN elegido como diana |
| WO2021237087A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
| WO2021236929A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| EP4600376A3 (en) * | 2020-06-02 | 2025-10-22 | 10X Genomics, Inc. | Spatial transcriptomics for antigen-receptors |
| AU2021283174A1 (en) | 2020-06-02 | 2023-01-05 | 10X Genomics, Inc. | Nucleic acid library methods |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| EP4421186B1 (en) | 2020-06-08 | 2025-08-13 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| ES2999535T3 (en) | 2020-06-10 | 2025-02-26 | 10X Genomics Inc | Methods for determining a location of an analyte in a biological sample |
| WO2021263111A1 (en) | 2020-06-25 | 2021-12-30 | 10X Genomics, Inc. | Spatial analysis of dna methylation |
| US12209280B1 (en) | 2020-07-06 | 2025-01-28 | 10X Genomics, Inc. | Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| CN112266962B (zh) * | 2020-11-13 | 2021-04-30 | 苏州科贝生物技术有限公司 | 一种联合检测急性淋巴细胞白血病的试剂盒 |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| AU2021409136A1 (en) | 2020-12-21 | 2023-06-29 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| EP4305196B1 (en) | 2021-04-14 | 2025-04-02 | 10X Genomics, Inc. | Methods of measuring mislocalization of an analyte |
| EP4320271B1 (en) | 2021-05-06 | 2025-03-19 | 10X Genomics, Inc. | Methods for increasing resolution of spatial analysis |
| ES3030033T3 (en) | 2021-06-03 | 2025-06-26 | 10X Genomics Inc | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| ES3011462T3 (en) | 2021-09-01 | 2025-04-07 | 10X Genomics Inc | Methods for blocking a capture probe on a spatial array |
| WO2023086880A1 (en) | 2021-11-10 | 2023-05-19 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of an analyte in a biological sample |
| WO2023102118A2 (en) | 2021-12-01 | 2023-06-08 | 10X Genomics, Inc. | Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5374524A (en) | 1988-05-10 | 1994-12-20 | E. I. Du Pont De Nemours And Company | Solution sandwich hybridization, capture and detection of amplified nucleic acids |
| US5827658A (en) | 1996-08-09 | 1998-10-27 | The United States Of America As Reprsented By The Department Of Health And Human Services | Isolation of amplified genes via cDNA subtractive hybridization |
| US7074556B2 (en) | 1999-03-02 | 2006-07-11 | Invitrogen Corporation | cDNA synthesis improvements |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| US6309836B1 (en) | 1999-10-05 | 2001-10-30 | Marek Kwiatkowski | Compounds for protecting hydroxyls and methods for their use |
| WO2001083696A2 (en) | 2000-04-28 | 2001-11-08 | Digital Gene Tech Inc | Methods for rapid isolation and sequence determination of gene-specific sequences |
| DK1454992T3 (da) | 2003-03-07 | 2006-10-02 | Ist Naz Stud Cura Dei Tumori | Anaplastisk lymfomakinaseassay, reagenser og sammensætninger deraf |
| US7226720B2 (en) | 2003-09-08 | 2007-06-05 | General Electric Company | Limited play data storage media and method for limiting access to data thereon |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| US7504509B2 (en) | 2003-12-19 | 2009-03-17 | Plexxikon, Inc. | Compounds and methods for development of Ret modulators |
| TWI311152B (en) * | 2004-09-17 | 2009-06-21 | Boehringer Ingelheim Rcv Gmbh & Co K | Host-vector system for antibiotic-free cole1 plasmid propagation |
| GB0421525D0 (en) | 2004-09-28 | 2004-10-27 | Novartis Ag | Inhibitors of protein kineses |
| US20070070349A1 (en) | 2005-09-23 | 2007-03-29 | Helicos Biosciences Corporation | Optical train and method for TIRF single molecule detection and analysis |
| US7220549B2 (en) | 2004-12-30 | 2007-05-22 | Helicos Biosciences Corporation | Stabilizing a nucleic acid for nucleic acid sequencing |
| GB0522310D0 (en) * | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| US7282337B1 (en) | 2006-04-14 | 2007-10-16 | Helicos Biosciences Corporation | Methods for increasing accuracy of nucleic acid sequencing |
| WO2009032167A1 (en) | 2007-08-29 | 2009-03-12 | Illumina Cambridge | Method for sequencing a polynucleotide template |
| WO2010006432A1 (en) | 2008-07-14 | 2010-01-21 | Queen's University At Kingston | Pharmaceutical compositions comprising ret inhibitors and methods for the treatment of cancer |
| US9416409B2 (en) | 2009-07-31 | 2016-08-16 | Ibis Biosciences, Inc. | Capture primers and capture sequence linked solid supports for molecular diagnostic tests |
| EP3006573B1 (en) | 2010-01-19 | 2018-03-07 | Verinata Health, Inc | Methods for determining fraction of fetal nucleic acids in maternal samples |
| EP2606154B1 (en) | 2010-08-20 | 2019-09-25 | Integenx Inc. | Integrated analysis system |
| US8722585B2 (en) | 2011-05-08 | 2014-05-13 | Yan Wang | Methods of making di-tagged DNA libraries from DNA or RNA using double-tagged oligonucleotides |
| CA2835942C (en) * | 2011-05-19 | 2019-01-22 | Sequenom, Inc. | Products and processes for multiplex nucleic acid identification |
| CN104093890B (zh) * | 2012-01-26 | 2016-04-20 | 纽亘技术公司 | 用于靶向核酸序列富集和高效文库产生的组合物和方法 |
| ES2905448T3 (es) | 2012-05-10 | 2022-04-08 | Massachusetts Gen Hospital | Métodos para determinar una secuencia nucleotídica |
| CA2877740A1 (en) | 2012-07-03 | 2014-01-09 | Integrated Dna Technologies, Inc. | Tm-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection |
| WO2014047678A1 (en) | 2012-09-25 | 2014-04-03 | Agriculture Victoria Services Pty Ltd | Method of producing a normalised nucleic acid library using solid state capture material |
| US20160186267A1 (en) * | 2013-02-21 | 2016-06-30 | Toma Biosciences, Inc. | Methods, compositions, and kits for nucleic acid analysis |
| GB2525568B (en) | 2013-03-15 | 2020-10-14 | Abvitro Llc | Single cell barcoding for antibody discovery |
| WO2014144822A2 (en) * | 2013-03-15 | 2014-09-18 | Immumetrix, Inc. | Methods and compositions for tagging and analyzing samples |
| AU2014361815A1 (en) | 2013-12-15 | 2016-05-26 | Academia Sinica | Methods for full-length amplification of double-stranded linear nucleic acids of unknown sequences |
| WO2015112948A2 (en) * | 2014-01-27 | 2015-07-30 | Iafrate Anthony John | Methods for determining a nucleotide sequence |
| WO2015112974A1 (en) * | 2014-01-27 | 2015-07-30 | The General Hospital Corporation | Methods of preparing nucleic acids for sequencing |
| DK3354732T3 (da) | 2014-06-23 | 2020-04-06 | Regeneron Pharma | Nukleasemedieret dna-samling |
| NZ730044A (en) | 2014-09-15 | 2024-08-30 | Abvitro Llc | High-throughput nucleotide library sequencing |
| WO2016138500A1 (en) * | 2015-02-27 | 2016-09-01 | Cellular Research, Inc. | Methods and compositions for barcoding nucleic acids for sequencing |
| CA2994601C (en) * | 2015-08-06 | 2020-08-25 | F. Hoffmann-La Roche Ag | Target enrichment by single probe primer extension |
| US11149312B2 (en) * | 2016-04-15 | 2021-10-19 | University Health Network | Hybrid-capture sequencing for determining immune cell clonality |
| EP4353830A3 (en) * | 2016-09-15 | 2024-07-03 | ArcherDX, LLC | Methods of nucleic acid sample preparation for analysis of cell-free dna |
| JP6997772B2 (ja) | 2016-09-15 | 2022-01-18 | アーチャーディーエックス， エルエルシー | 核酸サンプル調製の方法 |
| CN110191959B (zh) * | 2016-11-02 | 2024-04-09 | 阿谢尔德克斯有限责任公司 | 用于免疫组库测序的核酸样品制备方法 |
-
2017
- 2017-11-02 CN CN201780080046.0A patent/CN110191959B/zh active Active
- 2017-11-02 EP EP22209186.0A patent/EP4198140B1/en active Active
- 2017-11-02 EP EP17868046.8A patent/EP3535405B1/en active Active
- 2017-11-02 WO PCT/US2017/059804 patent/WO2018085599A2/en not_active Ceased
- 2017-11-02 US US15/802,408 patent/US10947582B2/en active Active
- 2017-11-02 AU AU2017355460A patent/AU2017355460B2/en active Active
- 2017-11-02 ES ES17868046T patent/ES2940620T3/es active Active
- 2017-11-02 CA CA3042391A patent/CA3042391A1/en active Pending
- 2017-11-02 JP JP2019522907A patent/JP7161991B2/ja active Active
-
2021
- 2021-02-17 US US17/177,740 patent/US20210180118A1/en not_active Abandoned
-
2022
- 2022-10-17 JP JP2022166273A patent/JP7483824B2/ja active Active
-
2023
- 2023-03-06 AU AU2023201370A patent/AU2023201370B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP7483824B2 (ja) | 2024-05-15 |
| EP3535405A2 (en) | 2019-09-11 |
| US20210180118A1 (en) | 2021-06-17 |
| WO2018085599A3 (en) | 2018-06-07 |
| AU2017355460A1 (en) | 2019-05-23 |
| EP4198140C0 (en) | 2024-09-04 |
| JP7161991B2 (ja) | 2022-10-27 |
| EP4198140B1 (en) | 2024-09-04 |
| US10947582B2 (en) | 2021-03-16 |
| WO2018085599A2 (en) | 2018-05-11 |
| ES2940620T3 (es) | 2023-05-09 |
| JP2019537439A (ja) | 2019-12-26 |
| EP3535405A4 (en) | 2020-07-15 |
| CN110191959A (zh) | 2019-08-30 |
| CN110191959B (zh) | 2024-04-09 |
| EP3535405B1 (en) | 2022-12-21 |
| AU2023201370A1 (en) | 2023-04-13 |
| AU2017355460B2 (en) | 2022-12-08 |
| AU2023201370B2 (en) | 2025-08-28 |
| EP4198140A1 (en) | 2023-06-21 |
| US20180155767A1 (en) | 2018-06-07 |
| JP2022185155A (ja) | 2022-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7483824B2 (ja) | 免疫レパートリーシーケンシングのための核酸サンプル調製の方法 | |
| US11390905B2 (en) | Methods of nucleic acid sample preparation for analysis of DNA | |
| US11795492B2 (en) | Methods of nucleic acid sample preparation | |
| JP2019532629A5 (OSRAM) | ||
| US20220282305A1 (en) | Methods of nucleic acid sample preparation | |
| HK40066065A (en) | Methods of nucleic acid sample preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220916 |
|
| EEER | Examination request |
Effective date: 20220916 |
|
| EEER | Examination request |
Effective date: 20220916 |