CA3036313A1 - Compositions comprising a cannabinoid receptor binding ligand - Google Patents
Compositions comprising a cannabinoid receptor binding ligand Download PDFInfo
- Publication number
- CA3036313A1 CA3036313A1 CA3036313A CA3036313A CA3036313A1 CA 3036313 A1 CA3036313 A1 CA 3036313A1 CA 3036313 A CA3036313 A CA 3036313A CA 3036313 A CA3036313 A CA 3036313A CA 3036313 A1 CA3036313 A1 CA 3036313A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical composition
- thc
- composition according
- cannabinoid receptor
- receptor binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
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- CYQFCXCEBYINGO-UHFFFAOYSA-N THC Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3C21 CYQFCXCEBYINGO-UHFFFAOYSA-N 0.000 claims description 137
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- XXGMIHXASFDFSM-UHFFFAOYSA-N Delta9-tetrahydrocannabinol Natural products CCCCCc1cc2OC(C)(C)C3CCC(=CC3c2c(O)c1O)C XXGMIHXASFDFSM-UHFFFAOYSA-N 0.000 claims description 31
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K31/02—Halogenated hydrocarbons
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
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| EP17168172.9 | 2017-04-26 | ||
| EP17168172 | 2017-04-26 | ||
| PCT/EP2017/074545 WO2018060282A1 (en) | 2016-09-28 | 2017-09-27 | Compositions comprising a cannabinoid receptor binding ligand |
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| CA3036313A1 true CA3036313A1 (en) | 2018-04-05 |
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| EP (2) | EP3698785A1 (enExample) |
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| KR (1) | KR20190060787A (enExample) |
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| CA (1) | CA3036313A1 (enExample) |
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| WO (1) | WO2018060282A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2564502T3 (es) | 2010-03-17 | 2016-03-23 | Novaliq Gmbh | Composición farmacéutica para el tratamiento de la presión intraocular aumentada |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| MX360469B (es) | 2012-09-12 | 2018-11-05 | Novaliq Gmbh | Composiciones que comprenden mezclas de alcanos semifluorados. |
| DE202013012753U1 (de) | 2012-09-12 | 2019-03-04 | Novaliq Gmbh | Zusammensetzungen semifluorierter Alkane zur Verwendung in der Behandlung von Keratoconjunctivitis Sicca |
| WO2015011199A1 (en) | 2013-07-23 | 2015-01-29 | Novaliq Gmbh | Stabilized antibody compositions |
| ES2953837T3 (es) | 2015-09-30 | 2023-11-16 | Novaliq Gmbh | 2-perfluorobutil pentano para administración oftálmica |
| CN120884568A (zh) | 2015-09-30 | 2025-11-04 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| AU2017260444B2 (en) | 2016-05-03 | 2019-05-09 | Pneuma Respiratory, Inc. | Droplet delivery device for delivery of fluids to the pulmonary system and methods of use |
| EP3442480B1 (en) | 2016-06-23 | 2019-10-02 | Novaliq GmbH | Topical administration method |
| US11684589B2 (en) | 2016-09-22 | 2023-06-27 | Novaliq Gmbh | Pharmaceutical compositions for use in the therapy of blepharitis |
| JP6869336B2 (ja) | 2016-09-23 | 2021-05-12 | ノバリック ゲーエムベーハー | シクロスポリンを含む眼科用組成物 |
| US10732712B2 (en) * | 2016-12-27 | 2020-08-04 | Facebook Technologies, Llc | Large scale integration of haptic devices |
| MX388460B (es) | 2017-04-21 | 2025-03-20 | Dermaliq Therapeutics Inc | Composiciones de yodo. |
| CN110650734B (zh) | 2017-05-12 | 2024-11-15 | 诺瓦利克有限责任公司 | 治疗与隐形眼镜有关病症的包含半氟化烷烃的药物组合物 |
| IL273531B2 (en) | 2017-09-27 | 2024-05-01 | Novaliq Gmbh | Ophthalmic compositions comprising latanoprost for use in the treatment of ocular diseases |
| US11896559B2 (en) | 2017-10-04 | 2024-02-13 | Novaliq Gmbh | Opthalmic compositions comprising F6H8 |
| CN118203735A (zh) | 2017-10-04 | 2024-06-18 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
| EP3706843B1 (en) | 2017-11-08 | 2024-06-26 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device with small volume ampoule |
| EP3758676A1 (en) | 2018-03-02 | 2021-01-06 | Novaliq GmbH | Pharmaceutical compositions comprising nebivolol |
| JP2021522219A (ja) | 2018-04-27 | 2021-08-30 | ノバリック ゲーエムベーハー | 緑内障の治療のためのタフルプロストを含む眼科用組成物 |
| WO2020074697A1 (en) | 2018-10-12 | 2020-04-16 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
| JP7665519B2 (ja) * | 2019-02-01 | 2025-04-21 | アルコン インコーポレイティド | 近視を治療するための化合物、組成物及び医薬組成物 |
| WO2020165132A1 (en) | 2019-02-13 | 2020-08-20 | Novaliq Gmbh | Compositions and methods for the treatment of ocular neovascularization |
| WO2021044045A1 (en) | 2019-09-06 | 2021-03-11 | Novaliq Gmbh | Ophthalmic composition for the treatment of uveitis |
| US12576039B2 (en) | 2020-05-18 | 2026-03-17 | Max Biology Co. Ltd. | Lipid-polymer compositions and methods of use |
| US20230363441A1 (en) * | 2020-09-24 | 2023-11-16 | Nicoventures Trading Limited | Formulation |
| JP2023543925A (ja) * | 2020-10-05 | 2023-10-18 | マックス バイオロジー カンパニー リミテッド | カンナビノイド含有組成物及び疾患の処置及び予防のための使用 |
| US11191751B1 (en) * | 2020-10-08 | 2021-12-07 | Ads Therapeutics Llc | Topical ophthalmological atropine free base compositions |
| WO2022169788A1 (en) | 2021-02-03 | 2022-08-11 | Ads Therapeutics Llc | Topical ophthalmological compositions |
| ES3040366T3 (en) | 2021-06-22 | 2025-10-30 | Pneuma Respiratory Inc | Droplet delivery device with push ejection |
| WO2023064477A1 (en) * | 2021-10-13 | 2023-04-20 | Pneuma Respiratory, Inc. | Compositions for delivery of cannabinoids |
| US12161795B2 (en) | 2022-07-18 | 2024-12-10 | Pneuma Respiratory, Inc. | Small step size and high resolution aerosol generation system and method |
| WO2026037894A1 (en) * | 2024-08-15 | 2026-02-19 | Dermaliq Therapeutics, Inc. | Semifluorinated alkane compositions for cleaning the skin |
| WO2026047389A1 (en) * | 2024-08-30 | 2026-03-05 | Vicadia Lda | Topical delivery of cannabinoid-based formulations for ocular allergy and inflammation in ophthalmic diseases |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19536504C2 (de) * | 1995-09-29 | 1999-09-23 | H Meinert | Verwendung fluorierter Alkane |
| US20080112895A1 (en) | 2006-08-04 | 2008-05-15 | Insys Therapeutics Inc. | Aqueous dronabinol formulations |
| US8222292B2 (en) | 2007-08-06 | 2012-07-17 | Insys Therapeutics, Inc. | Liquid cannabinoid formulations |
| WO2010051541A2 (en) | 2008-10-31 | 2010-05-06 | The University Of Mississippi | Compositions containing delta-9-thc-amino acid esters and process of preparation |
| AT509000B1 (de) * | 2009-10-23 | 2012-12-15 | Rausch Peter | Wasserlösliche zubereitungen von cannabinoiden und cannabispräparaten und deren anwendungen |
| EP2335735A1 (en) * | 2009-12-14 | 2011-06-22 | Novaliq GmbH | Pharmaceutical composition for treatment of dry eye syndrome |
| EP2444063A1 (en) * | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| US8758826B2 (en) | 2011-07-05 | 2014-06-24 | Wet Inc. | Cannabinoid receptor binding agents, compositions, and methods |
| DE202013012753U1 (de) * | 2012-09-12 | 2019-03-04 | Novaliq Gmbh | Zusammensetzungen semifluorierter Alkane zur Verwendung in der Behandlung von Keratoconjunctivitis Sicca |
| MX360469B (es) * | 2012-09-12 | 2018-11-05 | Novaliq Gmbh | Composiciones que comprenden mezclas de alcanos semifluorados. |
| CN106061490A (zh) | 2013-10-09 | 2016-10-26 | 列奥尼达斯·A·约翰逊 | 一种治疗和预防眼部疾病症状或体征的方法及组合物 |
| EP3071193B1 (en) | 2013-11-20 | 2020-01-08 | Panag Pharma Inc. | Compositions and methods for treatment of ocular inflammation and pain |
| MA41299A (fr) | 2014-12-30 | 2017-11-07 | Axim Biotechnologies Inc | Solutions ophtalmiques pour le traitement du glaucome et de la conjonctivite |
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2017
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- 2017-09-27 KR KR1020197010976A patent/KR20190060787A/ko not_active Ceased
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- 2017-09-27 BR BR112019006194A patent/BR112019006194A2/pt not_active IP Right Cessation
- 2017-09-27 JP JP2019516407A patent/JP2019534867A/ja active Pending
- 2017-09-27 CN CN201780058931.9A patent/CN109803650A/zh not_active Withdrawn
- 2017-09-27 CA CA3036313A patent/CA3036313A1/en not_active Withdrawn
- 2017-09-27 AU AU2017333420A patent/AU2017333420A1/en not_active Abandoned
- 2017-09-27 US US16/337,617 patent/US20190343793A1/en not_active Abandoned
- 2017-09-27 WO PCT/EP2017/074545 patent/WO2018060282A1/en not_active Ceased
- 2017-09-27 MX MX2019003544A patent/MX2019003544A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112019006194A2 (pt) | 2019-06-18 |
| US20190343793A1 (en) | 2019-11-14 |
| JP2019534867A (ja) | 2019-12-05 |
| AU2017333420A1 (en) | 2019-04-04 |
| EP3698785A1 (en) | 2020-08-26 |
| EP3518921B1 (en) | 2021-08-11 |
| CN109803650A (zh) | 2019-05-24 |
| WO2018060282A1 (en) | 2018-04-05 |
| EP3518921A1 (en) | 2019-08-07 |
| KR20190060787A (ko) | 2019-06-03 |
| MX2019003544A (es) | 2019-09-19 |
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Legal Events
| Date | Code | Title | Description |
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| AZWI | Withdrawn application |
Effective date: 20220225 |
|
| AZWI | Withdrawn application |
Effective date: 20220225 |