CA3036313A1 - Compositions comprising a cannabinoid receptor binding ligand - Google Patents
Compositions comprising a cannabinoid receptor binding ligand Download PDFInfo
- Publication number
- CA3036313A1 CA3036313A1 CA3036313A CA3036313A CA3036313A1 CA 3036313 A1 CA3036313 A1 CA 3036313A1 CA 3036313 A CA3036313 A CA 3036313A CA 3036313 A CA3036313 A CA 3036313A CA 3036313 A1 CA3036313 A1 CA 3036313A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical composition
- thc
- composition according
- cannabinoid receptor
- receptor binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
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- CYQFCXCEBYINGO-UHFFFAOYSA-N THC Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3C21 CYQFCXCEBYINGO-UHFFFAOYSA-N 0.000 claims description 137
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- XXGMIHXASFDFSM-UHFFFAOYSA-N Delta9-tetrahydrocannabinol Natural products CCCCCc1cc2OC(C)(C)C3CCC(=CC3c2c(O)c1O)C XXGMIHXASFDFSM-UHFFFAOYSA-N 0.000 claims description 31
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A—HUMAN NECESSITIES
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- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
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- Medicinal Preparation (AREA)
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| EP17168172 | 2017-04-26 | ||
| PCT/EP2017/074545 WO2018060282A1 (en) | 2016-09-28 | 2017-09-27 | Compositions comprising a cannabinoid receptor binding ligand |
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| ES2564502T3 (es) | 2010-03-17 | 2016-03-23 | Novaliq Gmbh | Composición farmacéutica para el tratamiento de la presión intraocular aumentada |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| CN113679699B (zh) | 2012-09-12 | 2022-10-28 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| WO2014041071A1 (en) | 2012-09-12 | 2014-03-20 | Novaliq Gmbh | Semifluorinated alkane compositions |
| DK3024484T3 (en) | 2013-07-23 | 2018-10-08 | Novaliq Gmbh | STABILIZED ANTIBODY COMPOSITIONS |
| KR102584063B1 (ko) | 2015-09-30 | 2023-09-27 | 노바리크 게엠베하 | 부분불소화 화합물 |
| CN110403923B (zh) | 2015-09-30 | 2021-09-21 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| JP6774508B2 (ja) | 2016-05-03 | 2020-10-28 | ニューマ・リスパイラトリー・インコーポレイテッド | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
| KR102257916B1 (ko) | 2016-06-23 | 2021-05-28 | 노바리크 게엠베하 | 드롭 디스펜서를 포함하는 키트 |
| MX2019003363A (es) | 2016-09-22 | 2019-10-02 | Novaliq Gmbh | Composiciones farmaceuticas para usarse en la terapia de la blefaritis. |
| ES2965677T3 (es) | 2016-09-23 | 2024-04-16 | Novaliq Gmbh | Composiciones oftálmicas que comprenden ciclosporina |
| US10732712B2 (en) * | 2016-12-27 | 2020-08-04 | Facebook Technologies, Llc | Large scale integration of haptic devices |
| AU2018253944B2 (en) | 2017-04-21 | 2022-09-15 | Dermaliq Therapeutics, Inc. | Iodine compositions |
| EP3621601A1 (en) | 2017-05-12 | 2020-03-18 | Novaliq GmbH | Pharmaceutical compositions comprosing semifluorinated alkanes for the treatment of contact lense-related conditions |
| MX2020003534A (es) | 2017-09-27 | 2020-07-29 | Novaliq Gmbh | Composiciones oftalmicas que comprenden latanoprost para usarse en el tratamiento de las enfermedades oculares. |
| CN111182893A (zh) | 2017-10-04 | 2020-05-19 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
| WO2019071008A1 (en) | 2017-10-04 | 2019-04-11 | Pneuma Respiratory, Inc. | ELECTRONIC DEVICE FOR DELIVERY OF LINEAR SHAPE ADMINISTRATION OPERATED BY BREATHING AND METHODS OF USE |
| US11771852B2 (en) | 2017-11-08 | 2023-10-03 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use |
| BR112020017838A2 (pt) | 2018-03-02 | 2020-12-22 | Novaliq Gmbh | Composições farmacêuticas que compreendem nebivolol |
| JP2021522219A (ja) | 2018-04-27 | 2021-08-30 | ノバリック ゲーエムベーハー | 緑内障の治療のためのタフルプロストを含む眼科用組成物 |
| EP4406533A3 (en) | 2018-10-12 | 2024-10-09 | Novaliq GmbH | Ophthalmic composition for treatment of dry eye disease |
| CN113614078A (zh) * | 2019-02-01 | 2021-11-05 | 爱瑞制药公司 | 用于治疗近视的化合物、组合物和方法 |
| US12397039B2 (en) | 2019-02-13 | 2025-08-26 | Novaliq Gmbh | Compositions and methods for the treatment of ocular neovascularization |
| EP4025235A1 (en) | 2019-09-06 | 2022-07-13 | Novaliq GmbH | Ophthalmic composition for the treatment of uveitis |
| AU2021347760B2 (en) * | 2020-09-24 | 2024-07-25 | Nicoventures Trading Limited | Formulation |
| CN116940349A (zh) * | 2020-10-05 | 2023-10-24 | 麦氏生物科技有限公司 | 含大麻素的组合物以及用于治疗和预防疾病的用途 |
| US11191751B1 (en) * | 2020-10-08 | 2021-12-07 | Ads Therapeutics Llc | Topical ophthalmological atropine free base compositions |
| EP4288151A4 (en) | 2021-02-03 | 2025-01-01 | ADS Therapeutics LLC | Topical ophthalmological compositions |
| US11793945B2 (en) | 2021-06-22 | 2023-10-24 | Pneuma Respiratory, Inc. | Droplet delivery device with push ejection |
| US20250228876A1 (en) * | 2021-10-13 | 2025-07-17 | Pneuma Respiratory, Inc. | Compositions for delivery of cannabinoids |
| WO2024020041A1 (en) | 2022-07-18 | 2024-01-25 | Pneuma Respiratory, Inc. | Small step size and high resolution aerosol generation system and method |
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| DE19536504C2 (de) * | 1995-09-29 | 1999-09-23 | H Meinert | Verwendung fluorierter Alkane |
| CN101516333A (zh) | 2006-08-04 | 2009-08-26 | 英西斯治疗学股份有限公司 | 水性屈大麻酚制剂 |
| US8222292B2 (en) | 2007-08-06 | 2012-07-17 | Insys Therapeutics, Inc. | Liquid cannabinoid formulations |
| CA2741862C (en) | 2008-10-31 | 2017-10-17 | Mahmoud A. Elsohly | Compositions containing delta-9-thc-amino acid esters and process of preparation |
| AT509000B1 (de) * | 2009-10-23 | 2012-12-15 | Rausch Peter | Wasserlösliche zubereitungen von cannabinoiden und cannabispräparaten und deren anwendungen |
| EP2335735A1 (en) * | 2009-12-14 | 2011-06-22 | Novaliq GmbH | Pharmaceutical composition for treatment of dry eye syndrome |
| EP2444063A1 (en) * | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| US8758826B2 (en) | 2011-07-05 | 2014-06-24 | Wet Inc. | Cannabinoid receptor binding agents, compositions, and methods |
| WO2014041071A1 (en) * | 2012-09-12 | 2014-03-20 | Novaliq Gmbh | Semifluorinated alkane compositions |
| CN113679699B (zh) * | 2012-09-12 | 2022-10-28 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| CN106061490A (zh) | 2013-10-09 | 2016-10-26 | 列奥尼达斯·A·约翰逊 | 一种治疗和预防眼部疾病症状或体征的方法及组合物 |
| WO2015074137A1 (en) | 2013-11-20 | 2015-05-28 | Mary Lynch | Compositions and methods for treatment of ocular inflammation and pain |
| MA41299A (fr) * | 2014-12-30 | 2017-11-07 | Axim Biotechnologies Inc | Solutions ophtalmiques pour le traitement du glaucome et de la conjonctivite |
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Also Published As
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| EP3518921B1 (en) | 2021-08-11 |
| WO2018060282A1 (en) | 2018-04-05 |
| US20190343793A1 (en) | 2019-11-14 |
| JP2019534867A (ja) | 2019-12-05 |
| MX2019003544A (es) | 2019-09-19 |
| CN109803650A (zh) | 2019-05-24 |
| BR112019006194A2 (pt) | 2019-06-18 |
| EP3518921A1 (en) | 2019-08-07 |
| EP3698785A1 (en) | 2020-08-26 |
| AU2017333420A1 (en) | 2019-04-04 |
| KR20190060787A (ko) | 2019-06-03 |
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Legal Events
| Date | Code | Title | Description |
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| AZWI | Withdrawn application |
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| AZWI | Withdrawn application |
Effective date: 20220225 |