CA3031399A1 - Biofusion proteins as anti-malaria vaccines - Google Patents
Biofusion proteins as anti-malaria vaccines Download PDFInfo
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- CA3031399A1 CA3031399A1 CA3031399A CA3031399A CA3031399A1 CA 3031399 A1 CA3031399 A1 CA 3031399A1 CA 3031399 A CA3031399 A CA 3031399A CA 3031399 A CA3031399 A CA 3031399A CA 3031399 A1 CA3031399 A1 CA 3031399A1
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- Prior art keywords
- msp3
- sequence
- protein
- antigenic
- fusion protein
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| EP16180544 | 2016-07-21 | ||
| PCT/SG2017/050369 WO2018017020A1 (en) | 2016-07-21 | 2017-07-21 | Biofusion proteins as anti-malaria vaccines |
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| CA3104833A1 (en) | 2018-07-16 | 2020-01-23 | Dcprime B.V. | A combination product for use in tumor vaccination. |
| WO2020033398A1 (en) * | 2018-08-06 | 2020-02-13 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for treating atii cell-dependent lung diseases |
| CA3119865A1 (en) * | 2018-11-23 | 2020-05-28 | Strike Pharma Ab | Bi-specific conjugates |
| US11052144B2 (en) | 2019-04-25 | 2021-07-06 | Dcprime B.V. | Methods of tumor vaccination |
| NL2023863B1 (en) * | 2019-09-20 | 2021-05-25 | Univ Griffith | Protein particles and uses thereof |
| CN111135290A (zh) * | 2020-01-16 | 2020-05-12 | 定山石生物科技(北京)有限公司 | 一种用于激活人体免疫细胞的多肽试剂 |
| US12091681B2 (en) | 2020-03-27 | 2024-09-17 | Mendus B.V. | Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy |
| WO2022003568A1 (en) | 2020-06-30 | 2022-01-06 | Dcprime B.V. | Use of leukemia-derived cells in ovarian cancer vaccines |
| KR20230135075A (ko) | 2021-01-22 | 2023-09-22 | 멘두스 비.브이. | 종양 백신접종 방법 |
| BE1029148B1 (fr) * | 2021-02-26 | 2022-09-26 | Curavac Europe | Vaccin pour un traitement therapeutique ou prophylactique de la myastenie grave |
| CN118207228B (zh) * | 2024-03-21 | 2025-03-14 | 中国科学院上海免疫与感染研究所 | 一种防治结合的多时期双靶点串联疟疾mRNA疫苗 |
| CN120209159B (zh) * | 2025-02-24 | 2026-08-04 | 南京澄实生物医药科技有限公司 | 一种预防疟原虫感染的融合蛋白和免疫原性组合物及应用 |
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| WO2000050077A1 (en) * | 1999-02-25 | 2000-08-31 | Smithkline Beecham Biologicals S.A. | Immunogens comprising a peptide and a carrier derived from h.influenzae protein d |
| DK200201741A (da) * | 2002-11-12 | 2003-09-16 | Statens Seruminstitut | Vaccine comprising chimeric malaria proteins derived from Plasmodium falciparum |
| US20050112133A1 (en) * | 2003-10-24 | 2005-05-26 | Pierre Druilhe | GLURP-MSP3 fusion protein, immunogenic compositions and malarial vaccines containing it |
| SI2336147T1 (sl) * | 2003-12-17 | 2014-08-29 | Janssen Alzheimer Immunotherapy | Konjugati nosilcev a beta imunogenih peptidov in postopki izdelave istih |
| KR101839496B1 (ko) * | 2011-06-01 | 2018-03-19 | 시아먼 유니버시티 | 디프테리아 독소 무독성 돌연변이 씨알엠197 또는 그의 단편을 포함하는 융합 단백질 |
| CA2903716C (en) * | 2013-03-08 | 2019-04-09 | Pfizer Inc. | Immunogenic fusion polypeptides |
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| TWI780058B (zh) | 2022-10-11 |
| AU2017300965B2 (en) | 2024-09-12 |
| CN109963586B (zh) | 2023-11-03 |
| EP4147715A1 (en) | 2023-03-15 |
| AU2017300965A1 (en) | 2019-02-07 |
| US20210038706A1 (en) | 2021-02-11 |
| JP2022116169A (ja) | 2022-08-09 |
| JP2019526274A (ja) | 2019-09-19 |
| TW201803907A (zh) | 2018-02-01 |
| US20220409712A1 (en) | 2022-12-29 |
| EP3487526B1 (en) | 2022-07-06 |
| BR112019001115A2 (pt) | 2019-06-25 |
| WO2018017020A1 (en) | 2018-01-25 |
| CN109963586A (zh) | 2019-07-02 |
| EP3487526A1 (en) | 2019-05-29 |
| JP7579298B2 (ja) | 2024-11-07 |
| KR20240154691A (ko) | 2024-10-25 |
| KR20190090775A (ko) | 2019-08-02 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20231018 |