CA3028334A1 - Engineered parasites for delivering protein to the central nervous system (cns) - Google Patents
Engineered parasites for delivering protein to the central nervous system (cns) Download PDFInfo
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| PCT/IL2017/050731 WO2018002938A1 (en) | 2016-06-29 | 2017-06-29 | Engineered parasites for delivering protein to the central nervous system (cns) |
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| JP7148415B2 (ja) * | 2016-06-29 | 2022-10-05 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド | タンパク質を中枢神経系(cns)に送達するための、組換え寄生虫 |
| BR112020021903A2 (pt) | 2018-04-27 | 2021-03-02 | Rocket Pharmaceuticals, Ltd. | terapia genética para degeneração do snc |
| CN109369796A (zh) * | 2018-09-27 | 2019-02-22 | 华中农业大学 | 一种检测羊弓形虫IgG抗体的酶联免疫方法 |
| CN110117609B (zh) * | 2019-05-20 | 2023-06-02 | 安徽农业大学 | 一种真菌基因敲除双荧光筛选方法 |
| EP3976071A1 (en) * | 2019-05-29 | 2022-04-06 | Université de Tours | Toxoplasma platform for treating cancer |
| EP3980059A1 (en) * | 2019-06-10 | 2022-04-13 | Infectious Disease Research Institute | Methods and compositions of astrovirus replicons |
| CN115379834A (zh) | 2020-03-11 | 2022-11-22 | 马萨诸塞眼科耳科诊所 | 用于nmnat1相关视网膜变性的基因疗法 |
| US11497801B2 (en) * | 2021-02-19 | 2022-11-15 | Sherryll Layton | Compositions and methods of enhancing immune responses |
| KR102561980B1 (ko) * | 2021-03-16 | 2023-08-01 | 한양대학교 에리카산학협력단 | 톡소포자충 gra9 단백질 또는 상기 단백질을 암호화하는 유전자를 유효성분으로 포함하는, 염증성 질환 예방 또는 치료용 약학적 조성물 |
| CN114524869B (zh) * | 2022-01-25 | 2023-06-09 | 华中农业大学 | 弓形虫微线体蛋白MIC17a及其应用 |
| KR102834734B1 (ko) * | 2022-04-28 | 2025-07-16 | 경희대학교 산학협력단 | 톡소포자충의 항원 rop4를 포함하는 재조합 백시니아 바이러스 백신 |
| WO2024064918A2 (en) * | 2022-09-23 | 2024-03-28 | Novome Biotechnologies, Inc. | Recombinant fusion polypeptides for secreting soluble, heterologous cargo |
| WO2025026988A1 (en) * | 2023-07-28 | 2025-02-06 | Theranexus | Mutated tfeb for treating lysosomal disorders |
| EP4560316A1 (en) * | 2023-11-23 | 2025-05-28 | Biokit Research & Development S.L.U. | Antigenic regions for the detection of anti-toxoplasma gondii igm antibodies |
| CN117925759B (zh) * | 2024-01-23 | 2024-07-02 | 通化康元生物科技有限公司 | 林蛙多肽制剂及其在食品和化妆品中的应用 |
| WO2025235741A1 (en) * | 2024-05-09 | 2025-11-13 | Grann Pharmaceuticals Inc. | Compositions and methods for modulating mecp2 activity |
| CN119925428B (zh) * | 2025-04-07 | 2025-07-11 | 天津捷昂康生物科技发展有限公司 | 一种树突状细胞在预防和/或治疗脱髓鞘疾病中的应用 |
| CN120424771B (zh) * | 2025-07-08 | 2025-10-17 | 华中农业大学 | 弓形虫mic19基因敲除虫株及其构建方法与应用 |
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| US5693325A (en) * | 1994-03-15 | 1997-12-02 | Molecumetics, Ltd. | Peptide vaccines and methods relating thereto |
| US8293224B2 (en) | 2000-02-07 | 2012-10-23 | Trustees Of Dartmouth College | Attenuated uracil auxotroph of an apicomplexan and use thereof |
| US20030096260A1 (en) * | 2001-10-09 | 2003-05-22 | Zhenhua Miao | Compositions useful as ligands for the formyl peptide receptor like 1 receptor and methods of use thereof |
| WO2004026903A2 (en) * | 2002-09-20 | 2004-04-01 | Akzo Nobel N.V. | Live antenuated parasite vaccine |
| US9757440B2 (en) | 2007-10-29 | 2017-09-12 | Trustees Of Dartmouth College | Method for treating cancer with Toxoplasma gondii vaccine |
| WO2016046321A1 (en) * | 2014-09-25 | 2016-03-31 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for treating cancer and infectious diseases |
| JP7148415B2 (ja) | 2016-06-29 | 2022-10-05 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド | タンパク質を中枢神経系(cns)に送達するための、組換え寄生虫 |
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2017
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- 2017-06-29 AU AU2017289886A patent/AU2017289886A1/en not_active Abandoned
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2024
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| US20220160790A1 (en) | 2022-05-26 |
| EP3478301A1 (en) | 2019-05-08 |
| AU2017289886A1 (en) | 2019-01-24 |
| US20200121731A1 (en) | 2020-04-23 |
| CN109757100A (zh) | 2019-05-14 |
| JP2019525744A (ja) | 2019-09-12 |
| KR20190021339A (ko) | 2019-03-05 |
| US11260081B2 (en) | 2022-03-01 |
| EP3478301A4 (en) | 2020-04-22 |
| JP7748681B2 (ja) | 2025-10-03 |
| JP2022184996A (ja) | 2022-12-13 |
| WO2018002938A1 (en) | 2018-01-04 |
| US12070476B2 (en) | 2024-08-27 |
| JP7497397B2 (ja) | 2024-06-10 |
| JP7148415B2 (ja) | 2022-10-05 |
| JP2024112982A (ja) | 2024-08-21 |
| US20250057892A1 (en) | 2025-02-20 |
| KR102513120B1 (ko) | 2023-03-27 |
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