CA3021995A1 - Bispecific binding proteins and uses thereof - Google Patents
Bispecific binding proteins and uses thereof Download PDFInfo
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- CA3021995A1 CA3021995A1 CA3021995A CA3021995A CA3021995A1 CA 3021995 A1 CA3021995 A1 CA 3021995A1 CA 3021995 A CA3021995 A CA 3021995A CA 3021995 A CA3021995 A CA 3021995A CA 3021995 A1 CA3021995 A1 CA 3021995A1
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Applications Claiming Priority (3)
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| US201662332788P | 2016-05-06 | 2016-05-06 | |
| US62/332,788 | 2016-05-06 | ||
| PCT/US2017/031356 WO2017193032A2 (en) | 2016-05-06 | 2017-05-05 | Bispecific binding proteins and uses thereof |
Publications (1)
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| CA3021995A1 true CA3021995A1 (en) | 2017-11-09 |
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| CA3021995A Pending CA3021995A1 (en) | 2016-05-06 | 2017-05-05 | Bispecific binding proteins and uses thereof |
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| WO (1) | WO2017193032A2 (zh) |
| ZA (1) | ZA201808160B (zh) |
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| WO2017011580A2 (en) | 2015-07-13 | 2017-01-19 | Cytomx Therapeutics, Inc. | Anti-pd-1 antibodies, activatable anti-pd-1 antibodies, and methods of use thereof |
| US11623957B2 (en) | 2015-12-07 | 2023-04-11 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and PSMA |
| TW202208440A (zh) | 2015-12-14 | 2022-03-01 | 美商宏觀基因股份有限公司 | 對於pd-1和ctla-4具有免疫反應性的雙特異性分子及其使用方法 |
| US11542332B2 (en) | 2016-03-26 | 2023-01-03 | Bioatla, Inc. | Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof |
| AR108377A1 (es) | 2016-05-06 | 2018-08-15 | Medimmune Llc | Proteínas de unión biespecíficas y sus usos |
| RU2022104399A (ru) | 2016-06-14 | 2022-05-05 | Ксенкор, Инк. | Биспецифические антитела-ингибиторы контрольных точек |
| EP3515951B1 (en) | 2016-09-23 | 2024-02-28 | Merus N.V. | Binding molecules that modulate a biological activity expressed by a cell |
| CA3041685A1 (en) * | 2016-11-01 | 2018-05-11 | Anaptysbio, Inc. | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| MX2019008208A (es) | 2017-01-09 | 2019-12-11 | Tesaro Inc | Métodos para tratar el cáncer con anticuerpos anti-tim-3. |
| HUE060983T2 (hu) | 2017-02-17 | 2023-05-28 | Denali Therapeutics Inc | Mesterségesen elõállított transferrin receptort kötõ polipeptidek |
| KR20200016899A (ko) | 2017-06-01 | 2020-02-17 | 싸이톰스 테라퓨틱스, 인크. | 활성화가능 항-pdl1 항체, 및 이의 이용 방법 |
| AU2018396964A1 (en) * | 2017-12-28 | 2020-08-06 | Nanjing Legend Biotech Co., Ltd. | Antibodies and variants thereof against PD-L1 |
| BR112020013133A2 (pt) * | 2017-12-29 | 2020-12-08 | Ap Biosciences, Inc. | Proteínas monospecíficas e bispecíficas com regulação do ponto de verificação imune para terapia do câncer |
| CN115991787A (zh) * | 2018-06-05 | 2023-04-21 | 江苏康宁杰瑞生物制药有限公司 | 二聚体及其用途 |
| JP2022507253A (ja) | 2018-11-13 | 2022-01-18 | コンパス セラピューティクス リミテッド ライアビリティ カンパニー | チェックポイント分子に対する多重特異性結合性構築物およびその使用 |
| CN114127107A (zh) * | 2019-04-01 | 2022-03-01 | Immetas治疗股份有限公司 | 靶向肿瘤微环境和免疫检查点蛋白的双特异性结合分子 |
| CN110229232B (zh) * | 2019-06-19 | 2020-05-19 | 北京智仁美博生物科技有限公司 | 双特异性抗体及其用途 |
| CN114616247A (zh) * | 2019-10-17 | 2022-06-10 | 江苏康宁杰瑞生物制药有限公司 | Ox40/pd-l1双特异性抗体 |
| JP2023504530A (ja) * | 2019-12-05 | 2023-02-03 | アーベル リミテッド | ＴｒｉＡｘ抗体の組成、その製造方法及び使用方法 |
| EP4056596A4 (en) * | 2020-03-20 | 2023-01-25 | RemeGen Co., Ltd. | BISPECIFIC FUSION PROTEIN AND USE THEREOF |
| CN114573704B (zh) * | 2021-03-10 | 2022-11-01 | 北京拓界生物医药科技有限公司 | Pd-1/ctla-4结合蛋白及其医药用途 |
| AU2022258299A1 (en) * | 2021-04-13 | 2023-11-16 | Medimmune, Llc | Bispecific antibody targeting pd-1 and tim-3 |
| JP2024515301A (ja) * | 2021-04-20 | 2024-04-08 | アムジエン・インコーポレーテツド | 多重特異性及び一価のｉｇｇ分子の会合における鎖対形成の静電ステアリングにおけるバランスのとれた電荷分布 |
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| CA2654317A1 (en) | 2006-06-12 | 2007-12-21 | Trubion Pharmaceuticals, Inc. | Single-chain multivalent binding proteins with effector function |
| EP3112382A1 (en) * | 2009-12-29 | 2017-01-04 | Emergent Product Development Seattle, LLC | Heterodimer binding proteins and uses thereof |
| JP2013532153A (ja) * | 2010-06-18 | 2013-08-15 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 慢性免疫病に対する免疫治療のためのｔｉｍ−３およびｐｄ−１に対する二重特異性抗体 |
| EP2407487A1 (en) * | 2010-07-14 | 2012-01-18 | F-Star Biotechnologische Forschungs - und Entwicklungsges. M.B.H. | Multispecific modular antibody |
| RU2625034C2 (ru) * | 2011-04-20 | 2017-07-11 | МЕДИММЬЮН, ЭлЭлСи | Антитела и другие молекулы, которые связывают в7-н1 и pd-1 |
| CA2854806A1 (en) | 2011-11-07 | 2013-05-16 | Medimmune, Llc | Multispecific and multivalent binding proteins and uses thereof |
| SI2794905T1 (sl) * | 2011-12-20 | 2020-08-31 | Medimmune, Llc | Modificirani polipeptidi za ogrodja bispecifičnega protitelesa |
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