CA3021681C - USE OF BETA-AGONISTS OF THYROID HORMONES - Google Patents

USE OF BETA-AGONISTS OF THYROID HORMONES

Info

Publication number
CA3021681C
CA3021681C CA3021681A CA3021681A CA3021681C CA 3021681 C CA3021681 C CA 3021681C CA 3021681 A CA3021681 A CA 3021681A CA 3021681 A CA3021681 A CA 3021681A CA 3021681 C CA3021681 C CA 3021681C
Authority
CA
Canada
Prior art keywords
group
alkyl
compound
receptor beta
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3021681A
Other languages
English (en)
French (fr)
Other versions
CA3021681A1 (en
Inventor
Brian Lian
Rochelle Hanley
Misha Dinerman
Mark Erion
Serge Boyer
Hongjian Jiang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Metabasis Therapeutics Inc
Viking Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabasis Therapeutics Inc, Viking Therapeutics Inc filed Critical Metabasis Therapeutics Inc
Publication of CA3021681A1 publication Critical patent/CA3021681A1/en
Application granted granted Critical
Publication of CA3021681C publication Critical patent/CA3021681C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3021681A 2016-04-22 2017-04-24 USE OF BETA-AGONISTS OF THYROID HORMONES Active CA3021681C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662326436P 2016-04-22 2016-04-22
US62/326,436 2016-04-22
PCT/US2017/029120 WO2017185087A1 (en) 2016-04-22 2017-04-24 Use of thyroid beta-agonists

Publications (2)

Publication Number Publication Date
CA3021681A1 CA3021681A1 (en) 2017-10-26
CA3021681C true CA3021681C (en) 2024-09-24

Family

ID=60116400

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3021681A Active CA3021681C (en) 2016-04-22 2017-04-24 USE OF BETA-AGONISTS OF THYROID HORMONES

Country Status (10)

Country Link
US (3) US11351183B2 (enExample)
EP (1) EP3445373B1 (enExample)
JP (1) JP6931042B2 (enExample)
KR (1) KR102407059B1 (enExample)
AU (1) AU2017252126B2 (enExample)
BR (1) BR112018071586A2 (enExample)
CA (1) CA3021681C (enExample)
ES (1) ES2992773T3 (enExample)
MX (1) MX385085B (enExample)
WO (1) WO2017185087A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3445373B1 (en) 2016-04-22 2024-08-21 Viking Therapeutics, Inc. Use of thyroid beta-agonists
KR20200138283A (ko) * 2018-03-22 2020-12-09 바이킹 테라퓨틱스 인코포레이티드 결정질 형태, 및 결정질 형태의 화합물을 제조하는 방법
EP3890747A4 (en) 2018-12-05 2022-08-03 Viking Therapeutics, Inc. COMPOSITIONS FOR THE TREATMENT OF FIBROSIS AND INFLAMMATION
US11752161B2 (en) 2020-03-27 2023-09-12 Gannex Pharma Co., Ltd. Pharmaceutical compositions, method of making and method of using thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040091455A1 (en) 2002-10-31 2004-05-13 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration
JP2007524656A (ja) 2003-10-23 2007-08-30 セルジーン・コーポレーション 疼痛を治療、改変および管理するための選択的サイトカイン阻害薬を含む組成物ならびにその使用方法
EP1689383B1 (en) 2003-11-19 2012-10-31 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
BRPI0520207A2 (pt) 2004-12-08 2012-09-25 Revision Therapeutics Inc uso de uma quantidade eficaz de um primeiro composto, e, medicamento sistemicamente formulado
MX2007014501A (es) * 2005-05-26 2008-02-07 Metabasis Therapeutics Inc Tiromimeticos novedosos que contienen acido fosfinico.
CA2606499C (en) 2005-05-26 2017-06-13 Metabasis Therapeutics, Inc. Thyromimetics for the treatment of fatty liver diseases
JPWO2007097289A1 (ja) 2006-02-20 2009-07-16 武田薬品工業株式会社 新規医薬
US20110071208A1 (en) 2009-06-05 2011-03-24 Protiva Biotherapeutics, Inc. Lipid encapsulated dicer-substrate interfering rna
WO2011038207A1 (en) * 2009-09-25 2011-03-31 Metabasis Therapeutics, Inc. Phosphorus-containing thyroid hormone receptor agonists and methods of use
CN107201364A (zh) 2011-06-21 2017-09-26 阿尔尼拉姆医药品有限公司 用于抑制载脂蛋白c‑iii(apoc3)基因表达的组合物与方法
JP2016517883A (ja) 2013-05-03 2016-06-20 オレゴン ヘルス アンド サイエンス ユニバーシティー X連鎖副腎白質ジストロフィーの処置におけるソベチロムの使用
EP3259246B1 (en) 2015-02-20 2023-03-22 Oregon Health & Science University Derivatives of sobetirome
EP3423379B1 (en) 2016-02-29 2020-04-01 Philip Morris Products S.a.s. Hinge-lid container and blank
MX2018012904A (es) 2016-04-22 2019-01-31 Viking Therapeutics Inc Uso de beta-agonistas del receptor de la hormona tiroidea.
EP3445373B1 (en) 2016-04-22 2024-08-21 Viking Therapeutics, Inc. Use of thyroid beta-agonists
CN109475121B (zh) 2016-05-18 2021-06-25 俄勒冈健康科学大学 苏比替罗衍生物

Also Published As

Publication number Publication date
MX2018012900A (es) 2019-07-01
BR112018071586A2 (pt) 2019-02-12
JP6931042B2 (ja) 2021-09-01
KR20190039027A (ko) 2019-04-10
US12440502B2 (en) 2025-10-14
AU2017252126B2 (en) 2023-02-09
EP3445373B1 (en) 2024-08-21
JP2019515033A (ja) 2019-06-06
MX385085B (es) 2025-03-14
WO2017185087A1 (en) 2017-10-26
US20220257618A1 (en) 2022-08-18
KR102407059B1 (ko) 2022-06-10
US11951114B2 (en) 2024-04-09
ES2992773T3 (en) 2024-12-18
US20250000880A1 (en) 2025-01-02
CA3021681A1 (en) 2017-10-26
EP3445373A4 (en) 2019-12-18
US11351183B2 (en) 2022-06-07
US20190321379A1 (en) 2019-10-24
AU2017252126A1 (en) 2018-11-08
EP3445373A1 (en) 2019-02-27

Similar Documents

Publication Publication Date Title
AU2023202321B2 (en) Use of thyroid beta-agonists
US12440502B2 (en) Use of thyroid beta-agonists
KR102220175B1 (ko) 헤테로사이클릭 글루타미나아제 억제제
AU2015274361B2 (en) Combination therapy with glutaminase inhibitors
KR20190125432A (ko) 글루타미나제 억제제를 사용하는 병용 요법
UA123700C2 (uk) Композиції і способи інгібування активності аргінази
US11382908B2 (en) Compositions and methods for treating inflammatory bowel disease
AU2016246521A1 (en) Treatment of lung cancer with inhibitors of glutaminase
HK40064933A (en) Use of thyroid beta-agonists
HK40013781A (en) Use of thyroid beta-agonists
HK40007271A (en) Use of thyroid beta-agonists
HK40013781B (zh) 甲状腺β-激动剂的应用
WO2017127417A1 (en) Phosphopantothenate compounds
AU2016326397A1 (en) Conjoint therapies with inhibitors of glucose production

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420

EEER Examination request

Effective date: 20220420