AU2017252126B2 - Use of thyroid beta-agonists - Google Patents

Use of thyroid beta-agonists Download PDF

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Publication number
AU2017252126B2
AU2017252126B2 AU2017252126A AU2017252126A AU2017252126B2 AU 2017252126 B2 AU2017252126 B2 AU 2017252126B2 AU 2017252126 A AU2017252126 A AU 2017252126A AU 2017252126 A AU2017252126 A AU 2017252126A AU 2017252126 B2 AU2017252126 B2 AU 2017252126B2
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AU
Australia
Prior art keywords
compound
group
alkyl
day
optionally substituted
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2017252126A
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English (en)
Other versions
AU2017252126A1 (en
Inventor
Serge Boyer
Misha DINERMAN
Mark Erion
Rochelle Hanley
Hongjian Jiang
Brian Lian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metabasis Therapeutics Inc
Viking Therapeutics Inc
Original Assignee
Metabasis Therapeutics Inc
Viking Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Metabasis Therapeutics Inc, Viking Therapeutics Inc filed Critical Metabasis Therapeutics Inc
Publication of AU2017252126A1 publication Critical patent/AU2017252126A1/en
Assigned to METABASIS THERAPEUTICS, INC., VIKING THERAPEUTICS, INC. reassignment METABASIS THERAPEUTICS, INC. Amend patent request/document other than specification (104) Assignors: HONGJIAN JIANG, METABASIS THERAPEUTICS, INC, VIKING THERAPEUTICS, INC.
Application granted granted Critical
Publication of AU2017252126B2 publication Critical patent/AU2017252126B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2017252126A 2016-04-22 2017-04-24 Use of thyroid beta-agonists Active AU2017252126B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662326436P 2016-04-22 2016-04-22
US62/326,436 2016-04-22
PCT/US2017/029120 WO2017185087A1 (en) 2016-04-22 2017-04-24 Use of thyroid beta-agonists

Publications (2)

Publication Number Publication Date
AU2017252126A1 AU2017252126A1 (en) 2018-11-08
AU2017252126B2 true AU2017252126B2 (en) 2023-02-09

Family

ID=60116400

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017252126A Active AU2017252126B2 (en) 2016-04-22 2017-04-24 Use of thyroid beta-agonists

Country Status (10)

Country Link
US (3) US11351183B2 (enExample)
EP (1) EP3445373B1 (enExample)
JP (1) JP6931042B2 (enExample)
KR (1) KR102407059B1 (enExample)
AU (1) AU2017252126B2 (enExample)
BR (1) BR112018071586A2 (enExample)
CA (1) CA3021681C (enExample)
ES (1) ES2992773T3 (enExample)
MX (1) MX385085B (enExample)
WO (1) WO2017185087A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3021681C (en) 2016-04-22 2024-09-24 Viking Therapeutics, Inc. USE OF BETA-AGONISTS OF THYROID HORMONES
AU2019238090B2 (en) 2018-03-22 2024-08-01 Viking Therapeutics, Inc. Crystalline forms and methods of producing crystalline forms of a compound
US12102646B2 (en) 2018-12-05 2024-10-01 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation
US11752161B2 (en) 2020-03-27 2023-09-12 Gannex Pharma Co., Ltd. Pharmaceutical compositions, method of making and method of using thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011038207A1 (en) * 2009-09-25 2011-03-31 Metabasis Therapeutics, Inc. Phosphorus-containing thyroid hormone receptor agonists and methods of use

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040091455A1 (en) 2002-10-31 2004-05-13 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration
JP2007524656A (ja) 2003-10-23 2007-08-30 セルジーン・コーポレーション 疼痛を治療、改変および管理するための選択的サイトカイン阻害薬を含む組成物ならびにその使用方法
RU2422450C2 (ru) 2003-11-19 2011-06-27 Метабазис Терапеутикс, Инк. Новые фосфорсодержащие тиромиметики
NZ561148A (en) 2004-12-08 2008-12-24 Sirion Therapeutics Inc Methods, assays and compositions for treating retinol-related diseases
CA2606499C (en) 2005-05-26 2017-06-13 Metabasis Therapeutics, Inc. Thyromimetics for the treatment of fatty liver diseases
CA2606498C (en) * 2005-05-26 2016-08-09 Metabasis Therapeutics, Inc. Novel phosphinic acid-containing thyromimetics
JPWO2007097289A1 (ja) 2006-02-20 2009-07-16 武田薬品工業株式会社 新規医薬
US20110071208A1 (en) 2009-06-05 2011-03-24 Protiva Biotherapeutics, Inc. Lipid encapsulated dicer-substrate interfering rna
EP3693464A3 (en) 2011-06-21 2020-12-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibition of expression of apolipoprotein c-iii (apoc3) genes
WO2014178892A1 (en) * 2013-05-03 2014-11-06 Scanlan Thomas S Use of sobetirome in the treatment of x-linked adrenolenoleukodystrophy
CN107848940A (zh) 2015-02-20 2018-03-27 俄勒冈健康科学大学 Sobeirome衍生物
KR102757616B1 (ko) 2016-02-29 2025-01-21 필립모리스 프로덕츠 에스.에이. 힌지 리드 용기 및 블랭크
CA3021681C (en) 2016-04-22 2024-09-24 Viking Therapeutics, Inc. USE OF BETA-AGONISTS OF THYROID HORMONES
WO2017185083A1 (en) 2016-04-22 2017-10-26 Viking Therapeutics Use of thyroid beta-agonists
ES2888915T3 (es) 2016-05-18 2022-01-10 Univ Oregon Health & Science Derivados de sobetirome

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011038207A1 (en) * 2009-09-25 2011-03-31 Metabasis Therapeutics, Inc. Phosphorus-containing thyroid hormone receptor agonists and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GENIN, E. C. ET AL.: "Induction of the adrenoleukodystrophy-related gene (ABCD2) by thyromimetics", THE JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2009) vol. 116, no. 1, 31 August 2009 (2009-08-31), pages 37 - 43 *

Also Published As

Publication number Publication date
US20250000880A1 (en) 2025-01-02
JP6931042B2 (ja) 2021-09-01
EP3445373B1 (en) 2024-08-21
BR112018071586A2 (pt) 2019-02-12
WO2017185087A1 (en) 2017-10-26
MX2018012900A (es) 2019-07-01
ES2992773T3 (en) 2024-12-18
EP3445373A4 (en) 2019-12-18
KR102407059B1 (ko) 2022-06-10
US20190321379A1 (en) 2019-10-24
AU2017252126A1 (en) 2018-11-08
KR20190039027A (ko) 2019-04-10
JP2019515033A (ja) 2019-06-06
CA3021681A1 (en) 2017-10-26
EP3445373A1 (en) 2019-02-27
CA3021681C (en) 2024-09-24
MX385085B (es) 2025-03-14
US12440502B2 (en) 2025-10-14
US11951114B2 (en) 2024-04-09
US20220257618A1 (en) 2022-08-18
US11351183B2 (en) 2022-06-07

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Legal Events

Date Code Title Description
HB Alteration of name in register

Owner name: VIKING THERAPEUTICS, INC.

Free format text: FORMER NAME(S): VIKING THERAPEUTICS, INC.; METABASIS THERAPEUTICS, INC; HONGJIAN JIANG

Owner name: METABASIS THERAPEUTICS, INC.

Free format text: FORMER NAME(S): VIKING THERAPEUTICS, INC.; METABASIS THERAPEUTICS, INC; HONGJIAN JIANG

FGA Letters patent sealed or granted (standard patent)