CA3021681C - USE OF BETA-AGONISTS OF THYROID HORMONES - Google Patents

USE OF BETA-AGONISTS OF THYROID HORMONES

Info

Publication number
CA3021681C
CA3021681C CA3021681A CA3021681A CA3021681C CA 3021681 C CA3021681 C CA 3021681C CA 3021681 A CA3021681 A CA 3021681A CA 3021681 A CA3021681 A CA 3021681A CA 3021681 C CA3021681 C CA 3021681C
Authority
CA
Canada
Prior art keywords
group
alkyl
compound
receptor beta
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3021681A
Other languages
English (en)
French (fr)
Other versions
CA3021681A1 (en
Inventor
Brian Lian
Rochelle Hanley
Misha Dinerman
Mark Erion
Serge Boyer
Hongjian Jiang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Metabasis Therapeutics Inc
Viking Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabasis Therapeutics Inc, Viking Therapeutics Inc filed Critical Metabasis Therapeutics Inc
Publication of CA3021681A1 publication Critical patent/CA3021681A1/en
Application granted granted Critical
Publication of CA3021681C publication Critical patent/CA3021681C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3021681A 2016-04-22 2017-04-24 USE OF BETA-AGONISTS OF THYROID HORMONES Active CA3021681C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662326436P 2016-04-22 2016-04-22
US62/326,436 2016-04-22
PCT/US2017/029120 WO2017185087A1 (en) 2016-04-22 2017-04-24 Use of thyroid beta-agonists

Publications (2)

Publication Number Publication Date
CA3021681A1 CA3021681A1 (en) 2017-10-26
CA3021681C true CA3021681C (en) 2024-09-24

Family

ID=60116400

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3021681A Active CA3021681C (en) 2016-04-22 2017-04-24 USE OF BETA-AGONISTS OF THYROID HORMONES

Country Status (10)

Country Link
US (3) US11351183B2 (cg-RX-API-DMAC7.html)
EP (1) EP3445373B1 (cg-RX-API-DMAC7.html)
JP (1) JP6931042B2 (cg-RX-API-DMAC7.html)
KR (1) KR102407059B1 (cg-RX-API-DMAC7.html)
AU (1) AU2017252126B2 (cg-RX-API-DMAC7.html)
BR (1) BR112018071586A2 (cg-RX-API-DMAC7.html)
CA (1) CA3021681C (cg-RX-API-DMAC7.html)
ES (1) ES2992773T3 (cg-RX-API-DMAC7.html)
MX (1) MX385085B (cg-RX-API-DMAC7.html)
WO (1) WO2017185087A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3445373B1 (en) 2016-04-22 2024-08-21 Viking Therapeutics, Inc. Use of thyroid beta-agonists
WO2019183004A1 (en) 2018-03-22 2019-09-26 Viking Therapeutics, Inc. Crystalline forms and methods of producing crystalline forms of a compound
US12102646B2 (en) 2018-12-05 2024-10-01 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation
US11752161B2 (en) 2020-03-27 2023-09-12 Gannex Pharma Co., Ltd. Pharmaceutical compositions, method of making and method of using thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040091455A1 (en) 2002-10-31 2004-05-13 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration
JP2007524656A (ja) 2003-10-23 2007-08-30 セルジーン・コーポレーション 疼痛を治療、改変および管理するための選択的サイトカイン阻害薬を含む組成物ならびにその使用方法
US7829552B2 (en) 2003-11-19 2010-11-09 Metabasis Therapeutics, Inc. Phosphorus-containing thyromimetics
KR100890410B1 (ko) 2004-12-08 2009-03-26 시리온 테라퓨틱스, 인크. 레티놀-관련 질환의 치료 방법, 검정법 및 치료용 조성물
MX2007014502A (es) 2005-05-26 2008-02-07 Metabasis Therapeutics Inc Tiromimeticos para el tratamiento de enfermedades del higado graso.
EP1890768A2 (en) * 2005-05-26 2008-02-27 Metabasis Therapeutics, Inc. Novel phosphinic acid-containing thyromimetics
US20090042857A1 (en) 2006-02-20 2009-02-12 Masuo Yamaoka Novel Pharmaceutical
US20110071208A1 (en) 2009-06-05 2011-03-24 Protiva Biotherapeutics, Inc. Lipid encapsulated dicer-substrate interfering rna
WO2011038207A1 (en) * 2009-09-25 2011-03-31 Metabasis Therapeutics, Inc. Phosphorus-containing thyroid hormone receptor agonists and methods of use
BR112013032645A2 (pt) 2011-06-21 2016-11-22 Alnylam Pharmaceuticals composições e métodos para inibição de expressão de apolipoproteína c-iii (apoc3)
WO2014178892A1 (en) * 2013-05-03 2014-11-06 Scanlan Thomas S Use of sobetirome in the treatment of x-linked adrenolenoleukodystrophy
AU2016219794A1 (en) 2015-02-20 2017-09-07 Oregon Health & Science University Derivatives of sobetirome
CN108602613B (zh) 2016-02-29 2020-06-16 菲利普莫里斯生产公司 铰接盖容器和坯料
EP3445372A4 (en) 2016-04-22 2020-03-25 Viking Therapeutics, Inc. USE OF THYROID BETA AGONISTS
EP3445373B1 (en) 2016-04-22 2024-08-21 Viking Therapeutics, Inc. Use of thyroid beta-agonists
LT3457851T (lt) 2016-05-18 2021-10-11 Oregon Health & Science University Sobetiromo dariniai

Also Published As

Publication number Publication date
KR102407059B1 (ko) 2022-06-10
AU2017252126B2 (en) 2023-02-09
US11351183B2 (en) 2022-06-07
KR20190039027A (ko) 2019-04-10
US20190321379A1 (en) 2019-10-24
US20250000880A1 (en) 2025-01-02
BR112018071586A2 (pt) 2019-02-12
US20220257618A1 (en) 2022-08-18
MX385085B (es) 2025-03-14
JP2019515033A (ja) 2019-06-06
US11951114B2 (en) 2024-04-09
EP3445373B1 (en) 2024-08-21
ES2992773T3 (en) 2024-12-18
AU2017252126A1 (en) 2018-11-08
JP6931042B2 (ja) 2021-09-01
MX2018012900A (es) 2019-07-01
US12440502B2 (en) 2025-10-14
EP3445373A4 (en) 2019-12-18
EP3445373A1 (en) 2019-02-27
CA3021681A1 (en) 2017-10-26
WO2017185087A1 (en) 2017-10-26

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