CA3020894A1 - Procedes et compositions pour le traitement de la maladie cliaque, sensibilite au gluten non cliaque et maladie cliaque refractaire - Google Patents
Procedes et compositions pour le traitement de la maladie cliaque, sensibilite au gluten non cliaque et maladie cliaque refractaire Download PDFInfo
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- 229910052700 potassium Inorganic materials 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
- 229960004919 procaine Drugs 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 239000000473 propyl gallate Substances 0.000 description 1
- 235000010388 propyl gallate Nutrition 0.000 description 1
- 229940075579 propyl gallate Drugs 0.000 description 1
- 201000010434 protein-losing enteropathy Diseases 0.000 description 1
- 229940117820 purinethol Drugs 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 235000021067 refined food Nutrition 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 230000007727 signaling mechanism Effects 0.000 description 1
- 230000037432 silent mutation Effects 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- WBHQBSYUUJJSRZ-UHFFFAOYSA-M sodium bisulfate Chemical compound [Na+].OS([O-])(=O)=O WBHQBSYUUJJSRZ-UHFFFAOYSA-M 0.000 description 1
- 229910000342 sodium bisulfate Inorganic materials 0.000 description 1
- 229940100996 sodium bisulfate Drugs 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 229940001584 sodium metabisulfite Drugs 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 229940001482 sodium sulfite Drugs 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000000392 somatic effect Effects 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000012414 sterilization procedure Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 235000020790 strict gluten-free diet Nutrition 0.000 description 1
- 108010033090 surfactant protein A receptor Proteins 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- AOBORMOPSGHCAX-DGHZZKTQSA-N tocofersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-DGHZZKTQSA-N 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000759 toxicological effect Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000012250 transgenic expression Methods 0.000 description 1
- 239000002451 tumor necrosis factor inhibitor Substances 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 238000009777 vacuum freeze-drying Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
L'invention concerne des procédés et des compositions pharmaceutiques pour le traitement de troubles inflammatoires, en particulier la maladie cliaque, la maladie cliaque réfractaire et la sensibilité au gluten non cliaque.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2016/037708 WO2017217985A1 (fr) | 2016-06-15 | 2016-06-15 | Procédés et compositions pour le traitement de la maladie cœliaque, sensibilité au gluten non cœliaque et maladie cœliaque réfractaire |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3020894A1 true CA3020894A1 (fr) | 2017-12-21 |
Family
ID=56292925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3020894A Pending CA3020894A1 (fr) | 2016-06-15 | 2016-06-15 | Procedes et compositions pour le traitement de la maladie cliaque, sensibilite au gluten non cliaque et maladie cliaque refractaire |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP3472202A1 (fr) |
JP (2) | JP2019521981A (fr) |
CN (1) | CN109311972A (fr) |
AR (1) | AR108790A1 (fr) |
AU (1) | AU2016411388A1 (fr) |
BR (1) | BR112018076287A2 (fr) |
CA (1) | CA3020894A1 (fr) |
EA (1) | EA201892707A1 (fr) |
MX (1) | MX2018015363A (fr) |
TW (2) | TW201803591A (fr) |
WO (1) | WO2017217985A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112019012570A8 (pt) * | 2016-12-21 | 2023-01-24 | Cephalon Inc | Anticorpos que se ligam especificamente à il-15 humana e seus usos, composição, método in vitro para detecção de il-15 ou um complexo de il-15 e receptor de il-15-alfa, polinucleotídeo, vetor e método de produção do dito anticorpo |
US20220008533A1 (en) * | 2018-10-31 | 2022-01-13 | Tiziana Life Sciences Plc | Composition and methods of treating inflammatory and autoimmune diseases |
AU2022325870A1 (en) | 2021-08-12 | 2024-02-08 | Amgen Inc. | Antibody formulations |
WO2024028448A1 (fr) | 2022-08-04 | 2024-02-08 | Calypso Biotech Sa | Inhibiteurs d'il-15 utiles pour le traitement de la dermatite atopique |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7247304B2 (en) * | 2001-08-23 | 2007-07-24 | Genmab A/S | Methods of treating using anti-IL-15 antibodies |
ZA200506724B (en) * | 2003-02-26 | 2007-03-28 | Genmab As | Human antibodies specific for interleukin 15 (IL-15) |
AU2010208637A1 (en) * | 2009-01-29 | 2011-08-04 | Abbvie Inc. | IL-1 binding proteins |
WO2011031986A1 (fr) * | 2009-09-10 | 2011-03-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health | Dosages du récepteur soluble à il-15 alpha |
EP2963057A1 (fr) * | 2014-07-02 | 2016-01-06 | Calypso Biotech SA | Anticorps pour IL-15 |
-
2016
- 2016-06-15 BR BR112018076287-3A patent/BR112018076287A2/pt active Search and Examination
- 2016-06-15 CN CN201680086774.8A patent/CN109311972A/zh active Pending
- 2016-06-15 AU AU2016411388A patent/AU2016411388A1/en active Pending
- 2016-06-15 WO PCT/US2016/037708 patent/WO2017217985A1/fr unknown
- 2016-06-15 EP EP16733804.5A patent/EP3472202A1/fr active Pending
- 2016-06-15 JP JP2018565345A patent/JP2019521981A/ja active Pending
- 2016-06-15 CA CA3020894A patent/CA3020894A1/fr active Pending
- 2016-06-15 MX MX2018015363A patent/MX2018015363A/es unknown
- 2016-06-15 EA EA201892707A patent/EA201892707A1/ru unknown
-
2017
- 2017-06-15 TW TW106119998A patent/TW201803591A/zh unknown
- 2017-06-15 TW TW111144466A patent/TW202327653A/zh unknown
- 2017-06-15 AR ARP170101652A patent/AR108790A1/es unknown
-
2021
- 2021-09-24 JP JP2021155175A patent/JP2022001577A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2018015363A (es) | 2019-04-15 |
BR112018076287A2 (pt) | 2019-03-26 |
EP3472202A1 (fr) | 2019-04-24 |
CN109311972A (zh) | 2019-02-05 |
EA201892707A1 (ru) | 2019-05-31 |
WO2017217985A1 (fr) | 2017-12-21 |
JP2019521981A (ja) | 2019-08-08 |
TW202327653A (zh) | 2023-07-16 |
AR108790A1 (es) | 2018-09-26 |
JP2022001577A (ja) | 2022-01-06 |
TW201803591A (zh) | 2018-02-01 |
AU2016411388A1 (en) | 2018-11-08 |
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