CA3015835A1 - Derivation of embryonic stem cells - Google Patents
Derivation of embryonic stem cellsInfo
- Publication number
- CA3015835A1 CA3015835A1 CA3015835A CA3015835A CA3015835A1 CA 3015835 A1 CA3015835 A1 CA 3015835A1 CA 3015835 A CA3015835 A CA 3015835A CA 3015835 A CA3015835 A CA 3015835A CA 3015835 A1 CA3015835 A1 CA 3015835A1
- Authority
- CA
- Canada
- Prior art keywords
- cell
- cells
- blastomere
- embryo
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0604—Whole embryos; Culture medium therefor
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
- C12N2501/91—Heparin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
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| US62482704P | 2004-11-04 | 2004-11-04 | |
| US60/624,827 | 2004-11-04 | ||
| US66248905P | 2005-03-15 | 2005-03-15 | |
| US60/662,489 | 2005-03-15 | ||
| US68715805P | 2005-06-03 | 2005-06-03 | |
| US60/687,158 | 2005-06-03 | ||
| US72306605P | 2005-10-03 | 2005-10-03 | |
| US60/723,066 | 2005-10-03 | ||
| US72677505P | 2005-10-14 | 2005-10-14 | |
| US60/726,775 | 2005-10-14 | ||
| CA2588088A CA2588088C (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2588088A Division CA2588088C (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
Publications (1)
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| CA3015835A1 true CA3015835A1 (en) | 2006-05-18 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| CA3015835A Abandoned CA3015835A1 (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
| CA2588088A Expired - Lifetime CA2588088C (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2588088A Expired - Lifetime CA2588088C (en) | 2004-11-04 | 2005-11-04 | Derivation of embryonic stem cells |
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| EP (3) | EP2479256A1 (https=) |
| JP (2) | JP5728676B2 (https=) |
| AU (1) | AU2005304978A1 (https=) |
| CA (2) | CA3015835A1 (https=) |
| HK (1) | HK1219295A1 (https=) |
| WO (1) | WO2006052646A2 (https=) |
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| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| BRPI0507074A (pt) | 2004-01-23 | 2007-06-19 | Advanced Cell Tech Inc | modalidades aperfeiçoadas para o tratamento de doenças degenerativas da retina |
| US7622108B2 (en) | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
| US7893315B2 (en) * | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| CA3015835A1 (en) | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| GB0507755D0 (en) * | 2005-04-16 | 2005-05-25 | Univ Sheffield | Cytotrophoblast stem cells |
| EP2302034B1 (en) | 2005-08-03 | 2020-10-14 | Astellas Institute for Regenerative Medicine | Improved methods of reprogramming animal somatic cells |
| CA2646491A1 (en) * | 2006-04-17 | 2007-10-25 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
| EP2029724A4 (en) * | 2006-05-03 | 2010-03-24 | Advanced Cell Tech Inc | DERIVATION FROM EMBRYONAL STEM CELLS AND EMBRYO-DERIVED CELLS |
| US20070298496A1 (en) * | 2006-06-23 | 2007-12-27 | Hung-Chih Kuo | Method of deriving pluripotent stem cells from a single blastomere |
| JP2010518857A (ja) | 2007-02-23 | 2010-06-03 | アドバンスド セル テクノロジー， インコーポレイテッド | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
| IL292561A (en) | 2007-10-12 | 2022-06-01 | Astellas Inst For Regenerative Medicine | Improved methods of rpe cell production and rpe cell preparations |
| WO2009067757A1 (en) * | 2007-11-30 | 2009-06-04 | Cytomatrix Pty Ltd | Methods of inducing pluripotency involving oct4 protein |
| EP2100954A1 (en) * | 2008-03-10 | 2009-09-16 | Assistance Publique - Hopitaux de Paris | Method for generating primate cardiac progenitor cells for clinical use from primate embryonic stem cells, and their applications |
| JP2009225675A (ja) * | 2008-03-19 | 2009-10-08 | Tohoku Univ | 上皮系細胞シートの作製のための同種皮膚由来フィーダー細胞 |
| US9127256B2 (en) | 2008-07-16 | 2015-09-08 | Dnavec Corporation | Method for production of reprogrammed cell using chromosomally unintegrated virus vector |
| AU2010289423B2 (en) | 2009-09-04 | 2014-03-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for enhancing genome stability and telomere elongation in embryonic stem cells |
| US10485829B2 (en) | 2009-11-17 | 2019-11-26 | Astellas Institute For Regenerative Medicine | Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells |
| AU2011279250B2 (en) | 2010-07-12 | 2014-12-04 | California Institute Of Technology | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| EP2596119B8 (en) | 2010-07-23 | 2021-06-02 | Astellas Institute for Regenerative Medicine | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
| WO2012013936A1 (en) * | 2010-07-30 | 2012-02-02 | Cambridge Enterprise Limited | Corticogenesis of human pluripotent cells |
| US10478206B2 (en) | 2011-04-29 | 2019-11-19 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| US20130142762A1 (en) * | 2011-11-07 | 2013-06-06 | Hina W. Chaudhry | Methods of cardiac repair |
| TWI719277B (zh) | 2011-11-14 | 2021-02-21 | 美商安斯泰來再生醫藥協會 | 人類rpe細胞之醫藥組合物及其用途 |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| CA2933083A1 (en) | 2013-12-11 | 2015-06-18 | Pfizer Limited | Method for producing retinal pigment epithelial cells |
| WO2016005985A2 (en) | 2014-07-09 | 2016-01-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Method for reprogramming cells |
| WO2016044271A2 (en) | 2014-09-15 | 2016-03-24 | Children's Medical Center Corporation | Methods and compositions to increase somatic cell nuclear transfer (scnt) efficiency by removing histone h3-lysine trimethylation |
| ES2980659T3 (es) | 2015-03-23 | 2024-10-02 | Astellas Inst For Regenerative Medicine | Ensayos mejorados de potencia de células de epitelio pigmentario retiniano (EPR) humano y progenitores de fotorreceptores |
| WO2021086911A1 (en) | 2019-10-30 | 2021-05-06 | Astellas Institute For Regenerative Medicine | Methods for producing retinal pigment epithelium cells |
| US20240368541A1 (en) | 2021-05-03 | 2024-11-07 | Astellas Institute For Regenerative Medicine | Methods of generating mature corneal endothelial cells |
| WO2022235869A1 (en) | 2021-05-07 | 2022-11-10 | Astellas Institute For Regenerative Medicine | Methods of generating mature hepatocytes |
| WO2022264132A1 (en) | 2021-06-13 | 2022-12-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Method for reprogramming human cells |
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| US6274705B1 (en) * | 1996-05-02 | 2001-08-14 | Aventis Pharmaceuticals Products Inc. | Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides |
| AU1439295A (en) * | 1993-12-17 | 1995-07-03 | Abs Global, Inc. | Ungulate preblastocyst derived embryonic stem cells and use thereof to produce cloned transgenic and chimeric ungulates |
| EP0739412B1 (en) * | 1993-12-23 | 2002-02-27 | Infigen, Inc. | ungulate EMBRYONIC STEM CELLS AS NUCLEAR DONORS AND NUCLEAR TRANSFER TECHNIQUES TO PRODUCE CHIMERIC AND TRANSGENIC ANIMALS |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| US20040199935A1 (en) | 1999-06-30 | 2004-10-07 | Chapman Karen B. | Cytoplasmic transfer to de-differentiate recipient cells |
| WO2001029206A1 (en) | 1999-10-15 | 2001-04-26 | Advanced Cell Technology, Inc. | Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells |
| AU784731B2 (en) | 1999-12-20 | 2006-06-08 | University Of Massachusetts | Embryonic or stem-like cells produced by cross species nuclear transplantation |
| JP2003533976A (ja) * | 2000-01-07 | 2003-11-18 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 胚分割による霊長類子孫のクローン性増殖 |
| US20030105082A1 (en) * | 2001-12-03 | 2003-06-05 | Murphy Greer Marechal | Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4 |
| DE10108412B4 (de) | 2001-02-21 | 2006-03-09 | Cevec Pharmaceuticals Gmbh | Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung |
| US20030082598A1 (en) | 2001-08-22 | 2003-05-01 | Ecker David J. | Molecular interaction sites of 23S ribosomal RNA and methods of modulating the same |
| CA2458575C (en) | 2001-08-24 | 2014-07-08 | Advanced Cell Technology, Inc. | Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy |
| US7247477B2 (en) * | 2002-04-16 | 2007-07-24 | Technion Research & Development Foundation Ltd. | Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells |
| US6699771B1 (en) * | 2002-08-06 | 2004-03-02 | Texas Instruments Incorporated | Process for optimizing junctions formed by solid phase epitaxy |
| AU2003296480A1 (en) * | 2002-12-10 | 2004-06-30 | The Wistar Institute | Method for programmed differentiation of stem cells |
| US20050118713A1 (en) | 2003-05-12 | 2005-06-02 | Nikolai Strelchenko | Morula derived embryonic stem cells |
| US20040229350A1 (en) * | 2003-05-12 | 2004-11-18 | Nikolai Strelchenko | Morula derived embryonic stem cells |
| TW200521236A (en) | 2003-12-22 | 2005-07-01 | Animal Technology Inst Taiwan | Method for generating non-human mammalian chimeric embryo |
| BRPI0507074A (pt) | 2004-01-23 | 2007-06-19 | Advanced Cell Tech Inc | modalidades aperfeiçoadas para o tratamento de doenças degenerativas da retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| US20070298453A1 (en) | 2004-02-12 | 2007-12-27 | University Of Newcastle Upon Tyne | Stem Cells |
| WO2006013519A1 (en) | 2004-07-26 | 2006-02-09 | Koninklijke Philips Electronics N.V. | Method of storing data in an information carrier, system for reading such an information carrier. |
| US20080262321A1 (en) | 2004-08-06 | 2008-10-23 | Ramot At Tel Aviv University Ltd. | Early Detection of Harmful Agents: Method, System and Kit |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| CA3015835A1 (en) | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| US7818929B2 (en) * | 2004-12-14 | 2010-10-26 | Anthony Hardwood Composites, Inc. | Laminated support mat |
| ES2549205T3 (es) * | 2005-10-14 | 2015-10-26 | Unisense Fertilitech A/S | Determinación de un cambio en una población de células |
| EP1847595B1 (en) * | 2006-04-20 | 2010-01-06 | Northern Sydney and Central Coast Area Health Service | Methods of assessing embryo viability |
| EP2029724A4 (en) * | 2006-05-03 | 2010-03-24 | Advanced Cell Tech Inc | DERIVATION FROM EMBRYONAL STEM CELLS AND EMBRYO-DERIVED CELLS |
| US20070298496A1 (en) | 2006-06-23 | 2007-12-27 | Hung-Chih Kuo | Method of deriving pluripotent stem cells from a single blastomere |
| JP2010518857A (ja) | 2007-02-23 | 2010-06-03 | アドバンスド セル テクノロジー， インコーポレイテッド | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
| CN102348811A (zh) * | 2009-01-13 | 2012-02-08 | 弗卢伊蒂格姆公司 | 单细胞核酸分析 |
| CN104232566B (zh) * | 2011-05-31 | 2016-11-16 | 尤尼森斯繁殖技术公司 | 基于卵裂球的卵裂和形态的胚胎质量评估 |
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2005
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- 2005-11-04 CA CA2588088A patent/CA2588088C/en not_active Expired - Lifetime
- 2005-11-04 EP EP11000551A patent/EP2479256A1/en not_active Withdrawn
- 2005-11-04 JP JP2007540021A patent/JP5728676B2/ja not_active Expired - Lifetime
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- 2005-11-04 AU AU2005304978A patent/AU2005304978A1/en not_active Abandoned
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2010
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| EP1812554A4 (en) | 2008-10-08 |
| EP2479256A1 (en) | 2012-07-25 |
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| HK1219295A1 (en) | 2017-03-31 |
| JP2013046623A (ja) | 2013-03-07 |
| US8642328B2 (en) | 2014-02-04 |
| JP5728676B2 (ja) | 2015-06-03 |
| US20140377865A1 (en) | 2014-12-25 |
| US7838727B2 (en) | 2010-11-23 |
| WO2006052646A3 (en) | 2006-09-28 |
| CA2588088A1 (en) | 2006-05-18 |
| AU2005304978A1 (en) | 2006-05-18 |
| US20060206953A1 (en) | 2006-09-14 |
| JP2008518616A (ja) | 2008-06-05 |
| US20110150842A1 (en) | 2011-06-23 |
| EP1812554A2 (en) | 2007-08-01 |
| CA2588088C (en) | 2018-10-09 |
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