CA3009983A1 - Lyposomal wnt3a for use in treating tooth sensitivity - Google Patents

Lyposomal wnt3a for use in treating tooth sensitivity Download PDF

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Publication number
CA3009983A1
CA3009983A1 CA3009983A CA3009983A CA3009983A1 CA 3009983 A1 CA3009983 A1 CA 3009983A1 CA 3009983 A CA3009983 A CA 3009983A CA 3009983 A CA3009983 A CA 3009983A CA 3009983 A1 CA3009983 A1 CA 3009983A1
Authority
CA
Canada
Prior art keywords
wnt
pulp
dentin
agent
tooth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3009983A
Other languages
English (en)
French (fr)
Inventor
Jill Helms
Daniel J. Hunter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of CA3009983A1 publication Critical patent/CA3009983A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/58—Preparations specially adapted for dental root treatment specially adapted for dental implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CA3009983A 2014-12-29 2015-12-28 Lyposomal wnt3a for use in treating tooth sensitivity Pending CA3009983A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462097502P 2014-12-29 2014-12-29
US62/097,502 2014-12-29
PCT/US2015/067683 WO2016109433A1 (en) 2014-12-29 2015-12-28 Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production

Publications (1)

Publication Number Publication Date
CA3009983A1 true CA3009983A1 (en) 2016-07-07

Family

ID=56284970

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3009983A Pending CA3009983A1 (en) 2014-12-29 2015-12-28 Lyposomal wnt3a for use in treating tooth sensitivity

Country Status (6)

Country Link
US (2) US10512668B2 (https=)
EP (1) EP3240562B1 (https=)
JP (1) JP6887948B2 (https=)
AU (1) AU2015374240B2 (https=)
CA (1) CA3009983A1 (https=)
WO (1) WO2016109433A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201617820D0 (en) * 2016-10-21 2016-12-07 King S College London Dental treatment
CN114469863B (zh) * 2021-11-26 2023-09-26 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2431464C2 (ru) * 2005-03-21 2011-10-20 Глаксо Груп Лимитед Композиция средства для чистки зубов, не содержащая алкилсульфата и ортофосфата, содержащая источник фторида и абразив для зубов на основе диоксида кремния
WO2008109119A2 (en) 2007-03-05 2008-09-12 The Board Of Trustees Of The Leland Stanford Junior University Wnt compositions and methods of use thereof
US20110171607A1 (en) 2007-10-25 2011-07-14 The Trustees Of Columbia University In The City Of New York Biopulp
CA2711262C (en) 2008-02-08 2015-06-23 Colgate-Palmolive Company Dental composition comprising a basic amino acid for alleviating tooth sensitivity
JP5584629B2 (ja) * 2008-02-08 2014-09-03 コルゲート・パーモリブ・カンパニー 二構成要素の口腔ケア製品
CN102686720B (zh) * 2009-11-17 2013-12-04 国立大学法人冈山大学 由牙髓细胞向成牙本质细胞的分化诱导方法
WO2011063371A1 (en) 2009-11-23 2011-05-26 University Of Medicine And Dentistry Of New Jersey Dentinal drug delivery composition
CN102811707A (zh) * 2010-02-08 2012-12-05 内布拉斯加大学董事委员会 结合生物矿物和金属的脂质体，它们的合成以及其使用方法
WO2012034070A1 (en) * 2010-09-09 2012-03-15 The Board Of Trustees Of The Leland Stanford Junior University Use of liposomal wnt compositions to enhance osseointegration
WO2012122081A2 (en) 2011-03-04 2012-09-13 President And Fellows Of Harvard College Dental treatment systems and uses thereof
CN105228557A (zh) 2013-03-21 2016-01-06 纽约市哥伦比亚大学理事会 用于牙组织再生的组合物和方法

Also Published As

Publication number Publication date
EP3240562A4 (en) 2018-08-15
US20200046801A1 (en) 2020-02-13
EP3240562B1 (en) 2023-03-22
JP6887948B2 (ja) 2021-06-16
US11260103B2 (en) 2022-03-01
US20180000893A1 (en) 2018-01-04
AU2015374240A1 (en) 2017-08-10
AU2015374240B2 (en) 2021-11-11
JP2018502094A (ja) 2018-01-25
US10512668B2 (en) 2019-12-24
EP3240562A1 (en) 2017-11-08
WO2016109433A1 (en) 2016-07-07

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