JP6887948B2 - 親油性薬剤を歯髄に送達するため、および象牙質生成を増強するための組成物および方法 - Google Patents

親油性薬剤を歯髄に送達するため、および象牙質生成を増強するための組成物および方法 Download PDF

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JP6887948B2
JP6887948B2 JP2017534221A JP2017534221A JP6887948B2 JP 6887948 B2 JP6887948 B2 JP 6887948B2 JP 2017534221 A JP2017534221 A JP 2017534221A JP 2017534221 A JP2017534221 A JP 2017534221A JP 6887948 B2 JP6887948 B2 JP 6887948B2
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wnt
pulp
dentin
composition
lacz
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Japanese (ja)
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JP2018502094A5 (https=
JP2018502094A (ja
Inventor
ジル ヘルムズ，
ジル ヘルムズ，
ダニエル ジェイ． ハンター，
ダニエル ジェイ． ハンター，
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/58—Preparations specially adapted for dental root treatment specially adapted for dental implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2017534221A 2014-12-29 2015-12-28 親油性薬剤を歯髄に送達するため、および象牙質生成を増強するための組成物および方法 Expired - Fee Related JP6887948B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462097502P 2014-12-29 2014-12-29
US62/097,502 2014-12-29
PCT/US2015/067683 WO2016109433A1 (en) 2014-12-29 2015-12-28 Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production

Publications (3)

Publication Number Publication Date
JP2018502094A JP2018502094A (ja) 2018-01-25
JP2018502094A5 JP2018502094A5 (https=) 2019-05-30
JP6887948B2 true JP6887948B2 (ja) 2021-06-16

Family

ID=56284970

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017534221A Expired - Fee Related JP6887948B2 (ja) 2014-12-29 2015-12-28 親油性薬剤を歯髄に送達するため、および象牙質生成を増強するための組成物および方法

Country Status (6)

Country Link
US (2) US10512668B2 (https=)
EP (1) EP3240562B1 (https=)
JP (1) JP6887948B2 (https=)
AU (1) AU2015374240B2 (https=)
CA (1) CA3009983A1 (https=)
WO (1) WO2016109433A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201617820D0 (en) * 2016-10-21 2016-12-07 King S College London Dental treatment
CN114469863B (zh) * 2021-11-26 2023-09-26 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2431464C2 (ru) * 2005-03-21 2011-10-20 Глаксо Груп Лимитед Композиция средства для чистки зубов, не содержащая алкилсульфата и ортофосфата, содержащая источник фторида и абразив для зубов на основе диоксида кремния
WO2008109119A2 (en) 2007-03-05 2008-09-12 The Board Of Trustees Of The Leland Stanford Junior University Wnt compositions and methods of use thereof
US20110171607A1 (en) 2007-10-25 2011-07-14 The Trustees Of Columbia University In The City Of New York Biopulp
CA2711262C (en) 2008-02-08 2015-06-23 Colgate-Palmolive Company Dental composition comprising a basic amino acid for alleviating tooth sensitivity
JP5584629B2 (ja) * 2008-02-08 2014-09-03 コルゲート・パーモリブ・カンパニー 二構成要素の口腔ケア製品
CN102686720B (zh) * 2009-11-17 2013-12-04 国立大学法人冈山大学 由牙髓细胞向成牙本质细胞的分化诱导方法
WO2011063371A1 (en) 2009-11-23 2011-05-26 University Of Medicine And Dentistry Of New Jersey Dentinal drug delivery composition
CN102811707A (zh) * 2010-02-08 2012-12-05 内布拉斯加大学董事委员会 结合生物矿物和金属的脂质体，它们的合成以及其使用方法
WO2012034070A1 (en) * 2010-09-09 2012-03-15 The Board Of Trustees Of The Leland Stanford Junior University Use of liposomal wnt compositions to enhance osseointegration
WO2012122081A2 (en) 2011-03-04 2012-09-13 President And Fellows Of Harvard College Dental treatment systems and uses thereof
CN105228557A (zh) 2013-03-21 2016-01-06 纽约市哥伦比亚大学理事会 用于牙组织再生的组合物和方法

Also Published As

Publication number Publication date
EP3240562A4 (en) 2018-08-15
US20200046801A1 (en) 2020-02-13
EP3240562B1 (en) 2023-03-22
CA3009983A1 (en) 2016-07-07
US11260103B2 (en) 2022-03-01
US20180000893A1 (en) 2018-01-04
AU2015374240A1 (en) 2017-08-10
AU2015374240B2 (en) 2021-11-11
JP2018502094A (ja) 2018-01-25
US10512668B2 (en) 2019-12-24
EP3240562A1 (en) 2017-11-08
WO2016109433A1 (en) 2016-07-07

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