CA3004665C - Transposon system, kit comprising the same, and uses thereof - Google Patents
Transposon system, kit comprising the same, and uses thereof Download PDFInfo
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- CA3004665C CA3004665C CA3004665A CA3004665A CA3004665C CA 3004665 C CA3004665 C CA 3004665C CA 3004665 A CA3004665 A CA 3004665A CA 3004665 A CA3004665 A CA 3004665A CA 3004665 C CA3004665 C CA 3004665C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C12N2800/00—Nucleic acids vectors
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562267270P | 2015-12-14 | 2015-12-14 | |
| US62/267,270 | 2015-12-14 | ||
| PCT/CN2016/109510 WO2017101749A1 (en) | 2015-12-14 | 2016-12-12 | Transposon system, kit comprising the same, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3004665A1 CA3004665A1 (en) | 2017-06-22 |
| CA3004665C true CA3004665C (en) | 2021-08-24 |
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| CA3004665A Active CA3004665C (en) | 2015-12-14 | 2016-12-12 | Transposon system, kit comprising the same, and uses thereof |
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| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US20190119636A1 (en) | 2017-10-23 | 2019-04-25 | Poseida Therapeutics, Inc. | Modified stem cell memory t cells, methods of making and methods of using same |
| KR102523318B1 (ko) | 2016-12-16 | 2023-04-18 | 비-모젠 바이오테크놀로지스, 인크. | 증진된 ｈＡＴ 패밀리 트랜스포존 매개 유전자 전달 및 연관된 조성물, 시스템, 및 방법 |
| US11278570B2 (en) | 2016-12-16 | 2022-03-22 | B-Mogen Biotechnologies, Inc. | Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods |
| EP3810764A2 (en) | 2018-06-21 | 2021-04-28 | B-Mogen Biotechnologies, Inc. | Enhanced hat family transposon-mediated gene transfer and associated compositions, systems, and methods |
| US20220042038A1 (en) * | 2018-12-20 | 2022-02-10 | Poseida Therapeutics, Inc. | Nanotransposon compositions and methods of use |
| AU2020290790A1 (en) * | 2019-06-11 | 2022-01-27 | Universitat Pompeu Fabra | Targeted gene editing constructs and methods of using the same |
| JP7693253B2 (ja) * | 2021-07-09 | 2025-06-17 | ネオジェンティーシ― コーポレーション | トランスポゾンシステムおよびその用途 |
| WO2023060589A1 (zh) * | 2021-10-15 | 2023-04-20 | 深圳市深研生物科技有限公司 | 多转座子系统 |
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| US6962810B2 (en) | 2000-10-31 | 2005-11-08 | University Of Notre Dame Du Lac | Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac |
| US20100154070A1 (en) * | 2005-05-14 | 2010-06-17 | Tian Xu | PiggyBac as a Tool for Genetic Manipulation and Analysis in Vertebrates |
| US20090042297A1 (en) * | 2007-06-01 | 2009-02-12 | George Jr Alfred L | Piggybac transposon-based vectors and methods of nucleic acid integration |
| KR20080041146A (ko) * | 2007-12-13 | 2008-05-09 | 푸단 유니버시티 | 척추동물에서의 유전자 조작 및 분석을 위한 도구로서의피기백 |
| SG174155A1 (en) | 2009-02-25 | 2011-10-28 | Univ Johns Hopkins | Piggybac transposon variants and methods of use |
| DE102011118018B4 (de) | 2011-10-25 | 2017-10-26 | Plasmidfactory Gmbh & Co. Kg | Minicircles mit Transpositionskassetten und ihre Verwendung zur Transformation von Zellen |
| US10398787B2 (en) * | 2012-10-26 | 2019-09-03 | Vrije Universiteit Brussel | Vectors for liver-directed gene therapy of hemophilia and methods and use thereof |
| CN102943092B (zh) | 2012-11-20 | 2014-12-10 | 西北农林科技大学 | 一种通用型PiggyBac转座子转基因载体及其制备方法 |
| KR20150085846A (ko) * | 2012-11-20 | 2015-07-24 | 제이.알.심프롯캄패니 | Tal-매개 전이 DNA 삽입방법 |
| CN104342453A (zh) * | 2013-08-06 | 2015-02-11 | 深圳先进技术研究院 | 含基因工程抗体基因表达盒的微环dna重组母质粒、含该表达盒的微环dna及应用 |
| EP3119896B1 (en) | 2014-03-21 | 2022-03-23 | The Sydney Children's Hospitals Network (Randwick and Westmead) | Stable gene transfer to proliferating cells |
| CA3246595A1 (en) * | 2014-04-09 | 2025-07-08 | Dna Twopointo Inc | Enhanced polynucleotide constructs for eukaryotic gene expression |
| SG11201608393TA (en) * | 2014-04-10 | 2016-11-29 | Seattle Children S Hospital Dba Seattle Children S Res Inst | Transgene genetic tags and methods of use |
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| CA3004665A1 (en) | 2017-06-22 |
| US11345926B2 (en) | 2022-05-31 |
| CN108474005B (zh) | 2022-10-21 |
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| JP6956416B2 (ja) | 2021-11-02 |
| MY184126A (en) | 2021-03-19 |
| MX380289B (es) | 2025-03-12 |
| KR20180092989A (ko) | 2018-08-20 |
| MX2018007203A (es) | 2018-11-12 |
| KR102249982B1 (ko) | 2021-05-11 |
| NZ742068A (en) | 2023-07-28 |
| TWI609960B (zh) | 2018-01-01 |
| WO2017101749A1 (en) | 2017-06-22 |
| AU2016373365A1 (en) | 2018-05-17 |
| US20180320196A1 (en) | 2018-11-08 |
| TW201720926A (zh) | 2017-06-16 |
| JP2019503653A (ja) | 2019-02-14 |
| CN108474005A (zh) | 2018-08-31 |
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