CA3002661C - Use of gene expression profiling to predict survival in cancer patient - Google Patents
Use of gene expression profiling to predict survival in cancer patient Download PDFInfo
- Publication number
- CA3002661C CA3002661C CA3002661A CA3002661A CA3002661C CA 3002661 C CA3002661 C CA 3002661C CA 3002661 A CA3002661 A CA 3002661A CA 3002661 A CA3002661 A CA 3002661A CA 3002661 C CA3002661 C CA 3002661C
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- CA
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- Prior art keywords
- gene
- copy number
- patient
- expression
- cks1b
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA3142853A CA3142853A1 (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57366904P | 2004-05-21 | 2004-05-21 | |
US60/573,669 | 2004-05-21 | ||
US60631904P | 2004-09-01 | 2004-09-01 | |
US60/606,319 | 2004-09-01 | ||
CA2567350A CA2567350C (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2567350A Division CA2567350C (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3142853A Division CA3142853A1 (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
Publications (2)
Publication Number | Publication Date |
---|---|
CA3002661A1 CA3002661A1 (en) | 2005-12-08 |
CA3002661C true CA3002661C (en) | 2022-03-15 |
Family
ID=35451480
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3002661A Active CA3002661C (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
CA2567350A Active CA2567350C (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
CA3142853A Pending CA3142853A1 (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2567350A Active CA2567350C (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
CA3142853A Pending CA3142853A1 (en) | 2004-05-21 | 2005-05-20 | Use of gene expression profiling to predict survival in cancer patient |
Country Status (6)
Country | Link |
---|---|
US (4) | US8843320B2 (es) |
EP (2) | EP2537942B1 (es) |
CA (3) | CA3002661C (es) |
DK (1) | DK2537942T3 (es) |
ES (1) | ES2555994T3 (es) |
WO (1) | WO2005116259A2 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2555994T3 (es) | 2004-05-21 | 2016-01-12 | The Board Of Trustees Of The University Of Arkansas System | Uso de perfiles de expresión génica para predecir la supervivencia en un paciente con cáncer |
US7914988B1 (en) * | 2006-03-31 | 2011-03-29 | Illumina, Inc. | Gene expression profiles to predict relapse of prostate cancer |
KR100893566B1 (ko) * | 2006-05-23 | 2009-04-17 | 재단법인 목암생명공학연구소 | Cks1b RNAi를 함유하는 항암용 조성물 |
US20090022731A1 (en) * | 2006-08-25 | 2009-01-22 | Wyeth | Arthritis-associated B cell gene expression |
WO2008057545A2 (en) * | 2006-11-07 | 2008-05-15 | The Board Of Trustees Of The University Of Arkansas | Gene expression profiling based identification of genomic signatures of high-risk multiple myeloma and uses thereof |
US20080274911A1 (en) * | 2006-11-07 | 2008-11-06 | Burington Bart E | Gene expression profiling based identification of genomic signature of high-risk multiple myeloma and uses thereof |
US20120129168A1 (en) * | 2009-04-10 | 2012-05-24 | Shingo Ichimiya | Tumor marker and use thereof |
WO2012149014A1 (en) | 2011-04-25 | 2012-11-01 | OSI Pharmaceuticals, LLC | Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment |
KR101389018B1 (ko) | 2011-07-19 | 2014-04-29 | 연세대학교 산학협력단 | 담도암 암 줄기세포 특성에 기초한 담도암 신규 바이오마커 및 그의 용도 |
JP2016525883A (ja) * | 2013-05-17 | 2016-09-01 | ナショナル ヘルス リサーチ インスティテュートス | 腺癌を予後的に分類及び治療する方法 |
EP3567123B1 (en) * | 2013-05-20 | 2021-11-10 | BioVentures, LLC | Gep5 model for multiple myeloma |
KR20160033780A (ko) * | 2013-08-22 | 2016-03-28 | 반다 파마슈티칼즈, 인코퍼레이티드. | 다발성 골수종 치료 |
KR20210127821A (ko) | 2013-08-22 | 2021-10-22 | 반다 파마슈티칼즈, 인코퍼레이티드. | 암 치료 |
CN103743910B (zh) * | 2013-12-27 | 2015-11-18 | 上海市计划生育科学研究所 | Ctbs蛋白作为精卵结合受体的靶点在筛选精卵结合抑制剂中的应用 |
US20170107580A1 (en) | 2015-10-15 | 2017-04-20 | Dendreon Pharmaceuticals, Inc. | Gene expression markers for predicting overall survival in subjects treated with sipuleucel-t |
CN106885908B (zh) * | 2015-12-23 | 2019-05-07 | 中国人民解放军第二军医大学 | 血清psmd4蛋白的检测试剂盒及其检测方法与应用 |
US11434301B2 (en) | 2016-11-11 | 2022-09-06 | The Regents Of The University Of California | Anti-CD46 antibodies and methods of use |
US20190025311A1 (en) * | 2017-07-21 | 2019-01-24 | Liquid Biopsy Research LLC | Methods for detection of plasma cell dyscrasia |
EP3476949A1 (en) | 2017-10-31 | 2019-05-01 | Centre National De La Recherche Scientifique | Prognosis method of multiple myeloma |
WO2021072112A1 (en) * | 2019-10-09 | 2021-04-15 | Hdt Bio Corp. | Detection of desmoglein-2 in cancers of epithelial origin |
CN116419747A (zh) | 2020-08-07 | 2023-07-11 | 福蒂斯治疗公司 | 靶向cd46的免疫偶联物及其使用方法 |
IL278473A (en) * | 2020-11-03 | 2022-06-01 | Yeda Res & Dev | Methods for diagnosing and determining treatment in multiple myeloma |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105149B1 (en) * | 1999-11-29 | 2006-09-12 | The Trustees Of Columbia University In The City Of New York | Isolation of five novel genes coding for new Fc receptors-type melanoma involved in the pathogenesis of lymphoma/myeloma |
AU4592601A (en) | 2000-03-21 | 2001-10-03 | Millennium Predictive Medicine | Novel genes, compositions, kits, and method for identification, assessment, prevention, and therapy of ovarian cancer |
US20030036163A1 (en) * | 2001-07-10 | 2003-02-20 | Myriad Genetics, Incorporated | Novel PN9826 nucleic acids and use thereof |
JP2005137202A (ja) | 2001-11-02 | 2005-06-02 | Fujisawa Pharmaceut Co Ltd | 多発性骨髄腫の分子診断方法 |
US8954283B2 (en) | 2001-11-07 | 2015-02-10 | John D. Shaughnessy, JR. | Diagnosis, prognosis and identification of potential therapeutic targets of multiple myeloma based on gene expression profiling |
US7935679B2 (en) * | 2001-11-07 | 2011-05-03 | Board Of Trustees Of The University Of Arkansas | Gene expression profiling based identification of CKS1B as a potential therapeutic target in multiple myeloma |
US7308364B2 (en) * | 2001-11-07 | 2007-12-11 | The University Of Arkansas For Medical Sciences | Diagnosis of multiple myeloma on gene expression profiling |
US7348418B2 (en) * | 2002-02-08 | 2008-03-25 | Memorial Sloan-Kettering Cancer Center | Carcinoma-related genes and polypeptides and methods of use thereof |
CA2500472A1 (en) | 2002-09-30 | 2004-04-15 | Oncotherapy Science, Inc. | Genes and polypeptides relating to human pancreatic cancers |
EP1581629B1 (en) | 2002-12-06 | 2015-04-01 | Millennium Pharmaceuticals, Inc. | Methods for the identification, assessment, and treatment of patients with proteasome inhibition therapy |
AU2004271192B2 (en) * | 2003-09-03 | 2011-11-17 | Government Of The United States Of America, As Represented By Secretary, Department Of Health And Human Services | Methods for identifying, diagnosing, and predicting survival of lymphomas |
US7741035B2 (en) | 2004-05-21 | 2010-06-22 | Board Of Trustees Of The University Of Arkansas | Use of gene expression profiling to predict survival in cancer patient |
ES2555994T3 (es) | 2004-05-21 | 2016-01-12 | The Board Of Trustees Of The University Of Arkansas System | Uso de perfiles de expresión génica para predecir la supervivencia en un paciente con cáncer |
US20100316629A1 (en) * | 2004-09-01 | 2010-12-16 | Shaughnessy Jr John D | Use of gene expression profiling to predict survival in cancer patient |
WO2008057545A2 (en) | 2006-11-07 | 2008-05-15 | The Board Of Trustees Of The University Of Arkansas | Gene expression profiling based identification of genomic signatures of high-risk multiple myeloma and uses thereof |
EP2390662A1 (en) | 2010-05-27 | 2011-11-30 | Erasmus University Medical Center Rotterdam | Molecular classification of multiple myeloma |
WO2011153545A2 (en) | 2010-06-04 | 2011-12-08 | Bioarray Therapeutics, Inc. | Gene expression signature as a predictor of chemotherapeutic response in breast cancer |
CA2854665A1 (en) | 2011-11-10 | 2013-05-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Gene expression signatures of neoplasm responsiveness to therapy |
-
2005
- 2005-05-20 ES ES12150351.0T patent/ES2555994T3/es active Active
- 2005-05-20 US US11/133,937 patent/US8843320B2/en active Active
- 2005-05-20 CA CA3002661A patent/CA3002661C/en active Active
- 2005-05-20 EP EP12150351.0A patent/EP2537942B1/en active Active
- 2005-05-20 CA CA2567350A patent/CA2567350C/en active Active
- 2005-05-20 DK DK12150351.0T patent/DK2537942T3/en active
- 2005-05-20 WO PCT/US2005/017731 patent/WO2005116259A2/en active Application Filing
- 2005-05-20 CA CA3142853A patent/CA3142853A1/en active Pending
- 2005-05-20 EP EP05780069A patent/EP1766086A4/en not_active Ceased
-
2013
- 2013-05-21 US US13/899,196 patent/US9650677B2/en active Active
-
2017
- 2017-05-12 US US15/593,937 patent/US10597729B2/en active Active
-
2020
- 2020-03-20 US US16/825,462 patent/US20200291486A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20170342501A1 (en) | 2017-11-30 |
EP1766086A2 (en) | 2007-03-28 |
CA2567350A1 (en) | 2005-12-08 |
US20200291486A1 (en) | 2020-09-17 |
CA3002661A1 (en) | 2005-12-08 |
CA2567350C (en) | 2018-06-12 |
EP1766086A4 (en) | 2009-10-28 |
WO2005116259A3 (en) | 2009-04-02 |
US20130338025A1 (en) | 2013-12-19 |
DK2537942T3 (en) | 2015-12-14 |
US20050260664A1 (en) | 2005-11-24 |
CA3142853A1 (en) | 2005-12-08 |
ES2555994T3 (es) | 2016-01-12 |
EP2537942B1 (en) | 2015-09-23 |
US9650677B2 (en) | 2017-05-16 |
EP2537942A1 (en) | 2012-12-26 |
US10597729B2 (en) | 2020-03-24 |
WO2005116259A2 (en) | 2005-12-08 |
US8843320B2 (en) | 2014-09-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20181018 |