CA2987919A1 - Fluorescence histo-tomography (fht) systems and methods - Google Patents

Fluorescence histo-tomography (fht) systems and methods Download PDF

Info

Publication number
CA2987919A1
CA2987919A1 CA2987919A CA2987919A CA2987919A1 CA 2987919 A1 CA2987919 A1 CA 2987919A1 CA 2987919 A CA2987919 A CA 2987919A CA 2987919 A CA2987919 A CA 2987919A CA 2987919 A1 CA2987919 A1 CA 2987919A1
Authority
CA
Canada
Prior art keywords
fluorescence
white light
fht
chamber
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2987919A
Other languages
English (en)
French (fr)
Inventor
John W. HOPPIN
John V. Frangioni
Robert William Holt
Mohammed Q. QUTAISH
Marc Edward Seaman
Mark W. Bordo
Jacob Yost Hesterman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emit Imaging Inc
Curadel LLC
Original Assignee
Invicro LLC
Curadel LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/158,928 external-priority patent/US9799113B2/en
Application filed by Invicro LLC, Curadel LLC filed Critical Invicro LLC
Publication of CA2987919A1 publication Critical patent/CA2987919A1/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome

Landscapes

  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Sampling And Sample Adjustment (AREA)
CA2987919A 2015-08-31 2016-08-31 Fluorescence histo-tomography (fht) systems and methods Pending CA2987919A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562211930P 2015-08-31 2015-08-31
US62/211,930 2015-08-31
US15/158,928 US9799113B2 (en) 2015-05-21 2016-05-19 Multi-spectral three dimensional imaging system and method
US15/158,928 2016-05-19
PCT/US2016/049708 WO2017040671A1 (en) 2015-08-31 2016-08-31 Fluorescence histo-tomography (fht) systems and methods

Publications (1)

Publication Number Publication Date
CA2987919A1 true CA2987919A1 (en) 2017-03-09

Family

ID=58188254

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2987919A Pending CA2987919A1 (en) 2015-08-31 2016-08-31 Fluorescence histo-tomography (fht) systems and methods

Country Status (6)

Country Link
EP (1) EP3298383A4 (enExample)
JP (2) JP6719123B2 (enExample)
KR (1) KR20180048586A (enExample)
AU (1) AU2016315795C1 (enExample)
CA (1) CA2987919A1 (enExample)
WO (1) WO2017040671A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10580130B2 (en) 2017-03-24 2020-03-03 Curadel, LLC Tissue identification by an imaging system using color information
US10694117B2 (en) * 2018-06-07 2020-06-23 Curadel, LLC Masking approach for imaging multi-peak fluorophores by an imaging system
KR102304036B1 (ko) * 2019-11-27 2021-09-17 울산과학기술원 연속 블록면 광간섭 현미경 장치
EP4105707A4 (en) 2020-03-19 2023-08-23 Sony Olympus Medical Solutions Inc. MEDICAL OBSERVATION SYSTEM, CONTROL DEVICE AND CONTROL METHOD
US20220020481A1 (en) 2020-07-20 2022-01-20 Abbott Laboratories Digital pass verification systems and methods
EP3964817B1 (en) 2020-09-03 2023-01-04 Inpeco SA Device and method for the automatic insertion of a reference material during the processing of a biological sample

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10123054A (ja) * 1996-10-23 1998-05-15 Kagaku Gijutsu Shinko Jigyodan 試料観察方法及びその装置
WO2003016878A2 (de) * 2001-08-09 2003-02-27 Biocam Gmbh System für die fluoreszenzdiagnostik
JP2006010620A (ja) * 2004-06-29 2006-01-12 Canon Inc 顕微鏡観察用断面試料の作成方法、およびウルトラミクロトーム
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
DE102005045961B4 (de) * 2005-09-26 2018-11-15 Siemens Healthcare Gmbh Verfahren und Vorrichtung zur Darstellung eines einen Fluoreszenzfarbstoff enthaltenden Gewebes
US7831075B2 (en) * 2005-10-20 2010-11-09 Case Western Reserve University Imaging system
KR100853655B1 (ko) * 2006-12-15 2008-08-25 한국전기연구원 피부 질환의 광학 진단 및 치료를 위한 장치, 광원 시스템 및 장치의 이용방법
US20090236541A1 (en) * 2008-03-24 2009-09-24 General Electric Company System and Methods for Optical Imaging
US8501435B2 (en) * 2008-10-09 2013-08-06 Sti Medical Systems, Llc Process for preserving three dimensional orientation to allow registering histopathological diagnoses of tissue to images of that tissue
US8747331B2 (en) * 2009-06-23 2014-06-10 Hologic, Inc. Variable angle guide holder for a biopsy guide plug
JP5564654B2 (ja) * 2010-05-31 2014-07-30 岩崎電気株式会社 Led照射装置
US20140135601A1 (en) * 2012-11-09 2014-05-15 Kestrel Labs, Inc. User replaceable optical subsystem for laser-based photoplethysmography
CN105307687A (zh) * 2013-03-15 2016-02-03 索隆-基特林癌症研究协会 多模态的基于二氧化硅的纳米粒子
CN111329450A (zh) * 2013-04-23 2020-06-26 雪松-西奈医学中心 用于从荧光团同时录制可见光图像和红外光图像的系统和方法

Also Published As

Publication number Publication date
AU2016315795C1 (en) 2022-03-10
EP3298383A4 (en) 2019-01-16
KR20180048586A (ko) 2018-05-10
EP3298383A1 (en) 2018-03-28
JP6719123B2 (ja) 2020-07-08
WO2017040671A1 (en) 2017-03-09
JP2018534584A (ja) 2018-11-22
JP2020169999A (ja) 2020-10-15
JP7093086B2 (ja) 2022-06-29
AU2016315795A1 (en) 2017-12-14
AU2016315795B2 (en) 2021-09-09

Similar Documents

Publication Publication Date Title
US12292437B2 (en) Fluorescence histo-tomography (FHT) systems and methods
AU2016315795B2 (en) Fluorescence histo-tomography (FHT) systems and methods
EP3194937B1 (en) Method for controlling depth of imaging in tissues using fluorescence microscopy under ultraviolet excitation following staining with fluorescing agents
EP3298588B1 (en) Multi-spectral three dimensional imaging system and method
CA2595213A1 (en) Method and apparatus for measuring cancerous changes from reflectance spectral measurements obtained during endoscopic imaging
CA2732962A1 (en) Dye application for confocal imaging of cellular microstructure
Thong et al. Toward real-time virtual biopsy of oral lesions using confocal laser endomicroscopy interfaced with embedded computing
WO2012112911A2 (en) Devices and methods for optical pathology
Croce et al. Human liver autofluorescence: an intrinsic tissue parameter discriminating normal and diseased conditions
KR20200083512A (ko) 수술 중의 외과적 마진 평가를 위한 이미징 방법 및 시스템
KR20210027255A (ko) 광학 흡수 및 산란 매체 내 표면 형광 물체의 깊이를 결정하고 물체의 형광 농도를 결정하기 위한 장치 및 방법
US9854963B2 (en) Apparatus and method for identifying one or more amyloid beta plaques in a plurality of discrete OCT retinal layers
CN104181142A (zh) 分子影像成像验证系统和方法
Jiang et al. Calibration of fluorescence imaging for tumor surgical margin delineation: multistep registration of fluorescence and histological images
Sarantopoulos et al. Imaging the bio-distribution of molecular probes using multispectral cryoslicing imaging
Byrd Advancing fluorescent contrast agent recovery methods for surgical guidance applications
CN204422419U (zh) 分子影像成像验证系统
Razansky et al. Optoacoustic Imaging of Adult Zebrafish

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20210806

EEER Examination request

Effective date: 20210806

EEER Examination request

Effective date: 20210806

EEER Examination request

Effective date: 20210806

EEER Examination request

Effective date: 20210806

EEER Examination request

Effective date: 20210806