CA2987919A1 - Systemes et procedes d'histo-tomographie de fluorescence (fht) - Google Patents

Systemes et procedes d'histo-tomographie de fluorescence (fht) Download PDF

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Publication number
CA2987919A1
CA2987919A1 CA2987919A CA2987919A CA2987919A1 CA 2987919 A1 CA2987919 A1 CA 2987919A1 CA 2987919 A CA2987919 A CA 2987919A CA 2987919 A CA2987919 A CA 2987919A CA 2987919 A1 CA2987919 A1 CA 2987919A1
Authority
CA
Canada
Prior art keywords
fluorescence
white light
fht
chamber
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2987919A
Other languages
English (en)
Inventor
John W. HOPPIN
John V. Frangioni
Robert William Holt
Mohammed Q. QUTAISH
Marc Edward Seaman
Mark W. Bordo
Jacob Yost Hesterman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emit Imaging Inc
Curadel LLC
Original Assignee
Invicro LLC
Curadel LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/158,928 external-priority patent/US9799113B2/en
Application filed by Invicro LLC, Curadel LLC filed Critical Invicro LLC
Publication of CA2987919A1 publication Critical patent/CA2987919A1/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Dans un mode de réalisation, l'invention concerne un système d'histo-tomographie de fluorescence (FHT). Le système FHT comprend un boîtier, une caméra de fluorescence située à l'intérieur du boîtier, une caméra à lumière blanche située à l'intérieur du boîtier, et une source de lumière de fluorescence située à l'intérieur du boîtier. Le système FHT comprend en outre une monture de support configurée pour porter le boîtier à l'intérieur d'une chambre d'un appareil de tranchage, de telle sorte que les caméras et la source de lumière de fluorescence sont dirigées vers une face de bloc d'un échantillon de tissu retenu à l'intérieur de la chambre.
CA2987919A 2015-08-31 2016-08-31 Systemes et procedes d'histo-tomographie de fluorescence (fht) Pending CA2987919A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562211930P 2015-08-31 2015-08-31
US62/211,930 2015-08-31
US15/158,928 US9799113B2 (en) 2015-05-21 2016-05-19 Multi-spectral three dimensional imaging system and method
US15/158,928 2016-05-19
PCT/US2016/049708 WO2017040671A1 (fr) 2015-08-31 2016-08-31 Systèmes et procédés d'histo-tomographie de fluorescence (fht)

Publications (1)

Publication Number Publication Date
CA2987919A1 true CA2987919A1 (fr) 2017-03-09

Family

ID=58188254

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2987919A Pending CA2987919A1 (fr) 2015-08-31 2016-08-31 Systemes et procedes d'histo-tomographie de fluorescence (fht)

Country Status (6)

Country Link
EP (1) EP3298383A4 (fr)
JP (2) JP6719123B2 (fr)
KR (1) KR20180048586A (fr)
AU (1) AU2016315795C1 (fr)
CA (1) CA2987919A1 (fr)
WO (1) WO2017040671A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10580130B2 (en) * 2017-03-24 2020-03-03 Curadel, LLC Tissue identification by an imaging system using color information
US10694117B2 (en) * 2018-06-07 2020-06-23 Curadel, LLC Masking approach for imaging multi-peak fluorophores by an imaging system
KR102304036B1 (ko) * 2019-11-27 2021-09-17 울산과학기술원 연속 블록면 광간섭 현미경 장치
EP4105707A4 (fr) * 2020-03-19 2023-08-23 Sony Olympus Medical Solutions Inc. Système d'observation médicale, dispositif de commande et procédé de commande
US20220020481A1 (en) 2020-07-20 2022-01-20 Abbott Laboratories Digital pass verification systems and methods
EP3964817B1 (fr) 2020-09-03 2023-01-04 Inpeco SA Dispositif et procédé pour l'insertion automatique d'un matériau de référence pendant le traitement d'un échantillon biologique

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10123054A (ja) * 1996-10-23 1998-05-15 Kagaku Gijutsu Shinko Jigyodan 試料観察方法及びその装置
WO2003016878A2 (fr) * 2001-08-09 2003-02-27 Biocam Gmbh Systeme de diagnostic par fluorescence
JP2006010620A (ja) * 2004-06-29 2006-01-12 Canon Inc 顕微鏡観察用断面試料の作成方法、およびウルトラミクロトーム
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
DE102005045961B4 (de) * 2005-09-26 2018-11-15 Siemens Healthcare Gmbh Verfahren und Vorrichtung zur Darstellung eines einen Fluoreszenzfarbstoff enthaltenden Gewebes
US7831075B2 (en) * 2005-10-20 2010-11-09 Case Western Reserve University Imaging system
KR100853655B1 (ko) * 2006-12-15 2008-08-25 한국전기연구원 피부 질환의 광학 진단 및 치료를 위한 장치, 광원 시스템 및 장치의 이용방법
US20090236541A1 (en) * 2008-03-24 2009-09-24 General Electric Company System and Methods for Optical Imaging
WO2010042217A1 (fr) * 2008-10-09 2010-04-15 Sti Medical Systems, Llc Procédé de maintien d’une orientation tridimensionnelle afin de permettre l'enregistrement de diagnostics histopathologiques de tissus
WO2010148503A1 (fr) * 2009-06-23 2010-12-29 Sentinelle Medical Inc. Support de guidage à angle variable pour bouchon de guidage de biopsie
JP5564654B2 (ja) * 2010-05-31 2014-07-30 岩崎電気株式会社 Ｌｅｄ照射装置
US20140135601A1 (en) * 2012-11-09 2014-05-15 Kestrel Labs, Inc. User replaceable optical subsystem for laser-based photoplethysmography
CN105307687A (zh) * 2013-03-15 2016-02-03 索隆-基特林癌症研究协会 多模态的基于二氧化硅的纳米粒子
CN105263390A (zh) * 2013-04-23 2016-01-20 雪松-西奈医学中心 用于从荧光团同时录制可见光图像和红外光图像的系统和方法

Also Published As

Publication number Publication date
JP2020169999A (ja) 2020-10-15
AU2016315795A1 (en) 2017-12-14
JP6719123B2 (ja) 2020-07-08
JP7093086B2 (ja) 2022-06-29
WO2017040671A1 (fr) 2017-03-09
AU2016315795C1 (en) 2022-03-10
EP3298383A4 (fr) 2019-01-16
EP3298383A1 (fr) 2018-03-28
JP2018534584A (ja) 2018-11-22
KR20180048586A (ko) 2018-05-10
AU2016315795B2 (en) 2021-09-09

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