CA2984569C - A scorpion venom heat-resistant synthetic peptide and applications thereof - Google Patents
A scorpion venom heat-resistant synthetic peptide and applications thereof Download PDFInfo
- Publication number
- CA2984569C CA2984569C CA2984569A CA2984569A CA2984569C CA 2984569 C CA2984569 C CA 2984569C CA 2984569 A CA2984569 A CA 2984569A CA 2984569 A CA2984569 A CA 2984569A CA 2984569 C CA2984569 C CA 2984569C
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- scorpion venom
- svhrsp
- resistant
- amino acid
- heat
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
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- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
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| CN201610645111.7A CN106220713B (zh) | 2016-08-08 | 2016-08-08 | 一种蝎毒耐热合成肽及其用途 |
| CN201610645111.7 | 2016-08-08 | ||
| PCT/CN2016/112078 WO2018028117A1 (zh) | 2016-08-08 | 2016-12-26 | 一种蝎毒耐热合成肽及其用途 |
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| CN109232718B (zh) * | 2018-11-09 | 2020-04-14 | 泰安市启航生物科技有限公司 | 一种合成肽sp2及其应用 |
| CN111647051B (zh) * | 2019-03-04 | 2022-02-01 | 中国医科大学 | 一种基于钠通道结构的短肽及其应用 |
| CN111896651B (zh) * | 2020-07-30 | 2021-04-23 | 山东大学 | 一种白眉蝮蛇蛇毒类凝血酶特征多肽及其应用 |
| CN114028537B (zh) * | 2021-11-27 | 2024-03-29 | 上海万锦医药科技有限公司 | 一种含有svhrsp蝎毒肽的药物组合物及其制备方法 |
| CN117224655B (zh) * | 2023-09-14 | 2024-05-14 | 大连医科大学 | 蝎毒耐热合成肽(svhrsp)在制备治疗肠道炎症的药物中的应用 |
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| US20030235902A1 (en) * | 2001-12-13 | 2003-12-25 | Kazuhiko Ishikawa | Heat-resistant thioredoxin and related enzymes |
| CN100465272C (zh) * | 2002-01-18 | 2009-03-04 | 中国科学院上海有机化学研究所 | 重组东亚马氏钳蝎毒rBmKaIT1的基因工程 |
| CN100516217C (zh) * | 2004-09-22 | 2009-07-22 | 山西大学 | 一种人工合成的蝎氯离子通道神经毒素基因-rBmK CTa |
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| CN101450966B (zh) * | 2007-11-29 | 2012-06-27 | 武汉摩尔生物科技有限公司 | 一种抗耐药菌的多肽及用途 |
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| CN103304630B (zh) * | 2012-03-07 | 2014-09-17 | 中国科学院大连化学物理研究所 | 东亚钳蝎蝎毒中的gpcr活性多肽及其提取分离和应用 |
| CN104341495A (zh) | 2013-07-31 | 2015-02-11 | 张万琴 | 一种蝎毒耐热多肽和制备方法及其应用 |
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