CA2977821A1 - Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis - Google Patents

Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis Download PDF

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Publication number
CA2977821A1
CA2977821A1 CA2977821A CA2977821A CA2977821A1 CA 2977821 A1 CA2977821 A1 CA 2977821A1 CA 2977821 A CA2977821 A CA 2977821A CA 2977821 A CA2977821 A CA 2977821A CA 2977821 A1 CA2977821 A1 CA 2977821A1
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CA
Canada
Prior art keywords
specific
lactobacillus
target
seq
vaginalis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2977821A
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English (en)
French (fr)
Inventor
Barbara L. EATON
Damon K. Getman
Traci Pawlowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
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Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Publication of CA2977821A1 publication Critical patent/CA2977821A1/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2977821A 2015-03-16 2016-03-16 Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis Pending CA2977821A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562133881P 2015-03-16 2015-03-16
US62/133,881 2015-03-16
US201562168405P 2015-05-29 2015-05-29
US201562168688P 2015-05-29 2015-05-29
US62/168,688 2015-05-29
US62/168,405 2015-05-29
PCT/US2016/022628 WO2016149357A1 (en) 2015-03-16 2016-03-16 Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis

Publications (1)

Publication Number Publication Date
CA2977821A1 true CA2977821A1 (en) 2016-09-22

Family

ID=56919495

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2977821A Pending CA2977821A1 (en) 2015-03-16 2016-03-16 Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis

Country Status (7)

Country Link
US (3) US10550438B2 (https=)
EP (2) EP3271484B1 (https=)
JP (3) JP6796593B2 (https=)
CN (1) CN107429297A (https=)
AU (2) AU2016233298B2 (https=)
CA (1) CA2977821A1 (https=)
WO (1) WO2016149357A1 (https=)

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CA3101173A1 (en) * 2018-05-23 2019-11-28 Ko Biolabs, Inc. Lactobacillus crispatus kbl693 strain and use thereof
US20220047653A1 (en) * 2018-08-10 2022-02-17 The Regents Of The University Of California Methods and compositions for treating and preventing inflammatory diseases
JP7389111B2 (ja) * 2018-08-24 2023-11-29 ジェン－プローブ・インコーポレーテッド 細菌の核酸を検出し、細菌性膣炎を診断するための組成物および方法
WO2020166708A1 (ja) * 2019-02-15 2020-08-20 コンビ株式会社 新規乳酸菌およびそれを含有する組成物
CN110283921A (zh) * 2019-07-12 2019-09-27 中生方政生物技术股份有限公司 加德纳杆菌、白色念珠菌双重检测的引物、探针组、试剂盒及检测方法
US20220205020A1 (en) * 2020-12-30 2022-06-30 Roche Molecular Systems, Inc. Compositions and methods for detection of bacteria and fungi associated with bacterial and candida vaginosis
EP4317511A4 (en) * 2021-04-02 2024-10-02 Baoshan Iron & Steel Co., Ltd. Low-carbon low-alloy q&p steel or hot-dip galvanized q&p steel with tensile strength greater than or equal to 1180 mpa, and manufacturing method therefor
EP4289964A4 (en) 2022-04-18 2024-10-09 Beijing OriginPoly Bio-Tec Co., Ltd. PRIMER-PROBE COMBINATION AND KIT FOR VAGINAL MICROECOSYSTEM DETECTION
CN114480694B (zh) * 2022-04-18 2022-06-17 北京起源聚禾生物科技有限公司 阴道微生态检测引物探针组合及试剂盒
WO2024006762A1 (en) * 2022-06-27 2024-01-04 The Uab Research Foundation Nucleic acid probes and their uses for the detection of prevotella bivia

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Also Published As

Publication number Publication date
CN107429297A (zh) 2017-12-01
AU2016233298A1 (en) 2017-09-14
JP6970268B2 (ja) 2021-11-24
AU2021277704A1 (en) 2021-12-23
JP2018508225A (ja) 2018-03-29
US12031187B2 (en) 2024-07-09
JP2022025106A (ja) 2022-02-09
US20180291430A1 (en) 2018-10-11
US20200109444A1 (en) 2020-04-09
EP3271484A1 (en) 2018-01-24
WO2016149357A1 (en) 2016-09-22
AU2016233298B2 (en) 2021-09-02
JP6796593B2 (ja) 2020-12-09
US11268156B2 (en) 2022-03-08
EP3910075C0 (en) 2024-12-11
AU2021277704B2 (en) 2022-04-28
US10550438B2 (en) 2020-02-04
EP3910075A1 (en) 2021-11-17
EP3271484B1 (en) 2021-06-02
JP2021035391A (ja) 2021-03-04
EP3271484A4 (en) 2018-11-14
US20210277451A1 (en) 2021-09-09
EP3910075B1 (en) 2024-12-11

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