CA2977808A1 - Methods and reagents for predicting predisposition to refractive error - Google Patents

Methods and reagents for predicting predisposition to refractive error Download PDF

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Publication number
CA2977808A1
CA2977808A1 CA2977808A CA2977808A CA2977808A1 CA 2977808 A1 CA2977808 A1 CA 2977808A1 CA 2977808 A CA2977808 A CA 2977808A CA 2977808 A CA2977808 A CA 2977808A CA 2977808 A1 CA2977808 A1 CA 2977808A1
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CA
Canada
Prior art keywords
exon
mrna
opsin gene
opsin
seq
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Application number
CA2977808A
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English (en)
French (fr)
Inventor
Jay Neitz
Maureen Neitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
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University of Washington
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Application filed by University of Washington filed Critical University of Washington
Publication of CA2977808A1 publication Critical patent/CA2977808A1/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2977808A 2015-02-27 2016-02-29 Methods and reagents for predicting predisposition to refractive error Pending CA2977808A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562126284P 2015-02-27 2015-02-27
US62/126,284 2015-02-27
PCT/US2016/020033 WO2016138512A1 (en) 2015-02-27 2016-02-29 Methods and reagents for predicting predisposition to refractive error

Publications (1)

Publication Number Publication Date
CA2977808A1 true CA2977808A1 (en) 2016-09-01

Family

ID=56789879

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2977808A Pending CA2977808A1 (en) 2015-02-27 2016-02-29 Methods and reagents for predicting predisposition to refractive error

Country Status (9)

Country Link
US (1) US10787707B2 (enExample)
EP (1) EP3261525B1 (enExample)
JP (1) JP7240097B2 (enExample)
KR (1) KR102551638B1 (enExample)
CN (1) CN107529987B (enExample)
AU (1) AU2016225033B2 (enExample)
CA (1) CA2977808A1 (enExample)
SG (2) SG11201706933TA (enExample)
WO (1) WO2016138512A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4589367A3 (en) 2016-08-01 2025-09-03 The University of Washington Ophthalmic lenses for treating myopia
EP3625620B1 (en) 2017-05-08 2025-09-10 SIGHTGLASS VISION, Inc. Methods for making contact lenses for reducing myopia
US10884264B2 (en) 2018-01-30 2021-01-05 Sightglass Vision, Inc. Ophthalmic lenses with light scattering for treating myopia
US12092905B2 (en) 2018-07-12 2024-09-17 Sightglass Vision, Inc. Methods and devices for reducing myopia in children
WO2020180817A1 (en) 2019-03-01 2020-09-10 Sightglass Vision, Inc. Ophthalmic lenses for reducing myopic progression and methods of making the same
JP2022529515A (ja) 2019-04-23 2022-06-22 サイトグラス・ヴィジョン・インコーポレイテッド 近視の進行を抑制するための動的光学特性を有する眼用レンズ

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US6582908B2 (en) 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US6706867B1 (en) 2000-12-19 2004-03-16 The United States Of America As Represented By The Department Of Health And Human Services DNA array sequence selection
EP1256632A3 (en) 2001-05-07 2004-01-02 Smithkline Beecham Corporation High throughput polymorphism screening
US20040110179A1 (en) 2002-03-15 2004-06-10 Shuber Anthony P. Method for alteration detection
DE60300792T2 (de) 2002-05-09 2005-12-01 Matsushita Electric Industrial Co., Ltd., Kadoma Inline-Elektronenkanone und Farbbildröhre mit selbiger
US20050208555A1 (en) 2004-03-16 2005-09-22 Affymetrix, Inc. Methods of genotyping
ITRM20050325A1 (it) 2005-06-23 2006-12-24 Univ Roma Isoforma di splicing alternativo del gene codificante per la proteina lox-1, usi e metodi relativi.
US7906289B2 (en) 2008-07-28 2011-03-15 Kaohsiung Medical University Using genetic polymorphisms of the BICD1 gene as a method for diagnosing and treating myopia
KR20110112290A (ko) 2008-12-22 2011-10-12 더 메디컬 컬리지 오브 위스콘신, 인크. 눈 길이의 성장을 제한하기 위한 방법 및 장치
US20120172419A1 (en) * 2009-09-15 2012-07-05 Medical College Of Wisconsin Research Foundation Inc. Reagents and methods for modulating cone photoreceptor activity
JP5901046B2 (ja) * 2010-02-19 2016-04-06 国立大学法人 千葉大学 OATP1B3mRNAの新規な選択的スプライシングバリアント
TWI631334B (zh) * 2011-01-14 2018-08-01 美國華盛頓大學商業中心 診斷及治療眼球長度相關病症之方法
WO2012116248A1 (en) 2011-02-24 2012-08-30 Massachusetts Institute Of Technology ALTERNATIVELY SPLICED mRNA ISOFORMS AS PROGNOSTIC INDICATORS FOR METASTATIC CANCER

Also Published As

Publication number Publication date
SG10202102575SA (en) 2021-04-29
EP3261525A4 (en) 2018-07-18
EP3261525B1 (en) 2021-09-29
JP2018512121A (ja) 2018-05-17
US20180112268A1 (en) 2018-04-26
US10787707B2 (en) 2020-09-29
AU2016225033A1 (en) 2017-10-12
EP3261525A1 (en) 2018-01-03
JP7240097B2 (ja) 2023-03-15
SG11201706933TA (en) 2017-09-28
KR102551638B1 (ko) 2023-07-05
AU2016225033B2 (en) 2021-11-11
HK1248498A1 (zh) 2018-10-19
CN107529987A (zh) 2018-01-02
WO2016138512A1 (en) 2016-09-01
KR20170122212A (ko) 2017-11-03
CN107529987B (zh) 2021-04-20

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