CA2967287A1 - Compositions for treating acute, post-operative, or chronic pain and methods of using the same - Google Patents
Compositions for treating acute, post-operative, or chronic pain and methods of using the same Download PDFInfo
- Publication number
- CA2967287A1 CA2967287A1 CA2967287A CA2967287A CA2967287A1 CA 2967287 A1 CA2967287 A1 CA 2967287A1 CA 2967287 A CA2967287 A CA 2967287A CA 2967287 A CA2967287 A CA 2967287A CA 2967287 A1 CA2967287 A1 CA 2967287A1
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- CA
- Canada
- Prior art keywords
- biodegradable carrier
- anticonvulsant agent
- composition
- days
- inclusive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A—HUMAN NECESSITIES
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
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- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US201462081162P | 2014-11-18 | 2014-11-18 | |
| US62/081,162 | 2014-11-18 | ||
| PCT/US2015/017112 WO2016081022A1 (en) | 2014-11-18 | 2015-02-23 | Compositions for treating acute, post-operative, or chronic pain and methods of using the same |
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| CA2967287A1 true CA2967287A1 (en) | 2016-05-26 |
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| CA2967335A Abandoned CA2967335A1 (en) | 2014-11-18 | 2015-11-11 | Compositions for treating acute, post-operative, or chronic pain and methods of using the same |
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| CA2967335A Abandoned CA2967335A1 (en) | 2014-11-18 | 2015-11-11 | Compositions for treating acute, post-operative, or chronic pain and methods of using the same |
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| US20170239183A1 (en) * | 2016-02-23 | 2017-08-24 | PixarBio Corporation | COMPOSITIONS COMPRISING NAv1.7 SELECTIVE INHIBITORS FOR TREATING ACUTE, POST-OPERATIVE, OR CHRONIC PAIN AND METHODS OF USING THE SAME |
| CN106902095B (zh) * | 2017-03-08 | 2021-11-05 | 东北林业大学 | 一种集化疗与免疫疗法为一体的载黄芩苷纳米制剂及其制备方法 |
| US20180338929A1 (en) * | 2017-05-23 | 2018-11-29 | Soon Kap Hahn | Method and Compounds for Treating Peripheral Neuropathy |
| US11571429B2 (en) * | 2017-05-23 | 2023-02-07 | Upexmed Co. Ltd. | Method and compounds for treating peripheral neuropathy |
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| US4166800A (en) * | 1977-08-25 | 1979-09-04 | Sandoz, Inc. | Processes for preparation of microspheres |
| IL86211A (en) * | 1987-05-04 | 1992-03-29 | Ciba Geigy Ag | Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation |
| US5948384A (en) * | 1990-09-14 | 1999-09-07 | Syngenix Limited | Particulate agents |
| US20030056896A1 (en) * | 1995-05-12 | 2003-03-27 | Frank Jao | Effective therapy for epilepsies |
| CN1156961A (zh) * | 1995-06-09 | 1997-08-13 | 欧罗赛铁克股份有限公司 | 产生长效局部麻醉的制剂和方法 |
| CA2547531C (en) * | 2002-11-26 | 2013-11-12 | Seacoast Neuroscience, Inc. | Buoyant polymer particles for delivery of therapeutic agents to the central nervous system |
| EP1781257B1 (en) * | 2004-08-13 | 2018-12-19 | Emisphere Technologies, Inc. | Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent |
| BRPI0518829A2 (pt) * | 2004-12-06 | 2008-12-09 | Avigen Inc | mÉtodo para o tratamento de dor neuropÁtica e sÍndromes associadas |
| US20100204178A1 (en) * | 2006-10-02 | 2010-08-12 | James Cloyd | Novel parenteral carbamazepine formulation |
| WO2007120818A2 (en) * | 2006-04-12 | 2007-10-25 | Massachusetts Institute Of Technology | Compositions and methods for inhibiting adhesions |
| US20070253994A1 (en) * | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Intraspinal Drug Delivery Methods and Devices To Alleviate Chronic Pelvic Pain |
| JP5630998B2 (ja) * | 2006-05-15 | 2014-11-26 | マサチューセッツ インスティテュート オブ テクノロジー | 機能的粒子のためのポリマー |
| US20110052697A1 (en) * | 2006-05-17 | 2011-03-03 | Gwangju Institute Of Science & Technology | Aptamer-Directed Drug Delivery |
| GB0625322D0 (en) * | 2006-12-19 | 2007-01-24 | Pharmakodex Ltd | Pharmaceutical compositions |
| ES2689322T3 (es) * | 2008-03-04 | 2018-11-13 | Teva Pharmaceuticals International Gmbh | Métodos para tratar el dolor crónico |
| CN102083419A (zh) * | 2008-07-01 | 2011-06-01 | 日东电工株式会社 | 包含表面被覆了的微粒的医药组合物 |
| AU2010278601A1 (en) * | 2009-07-31 | 2012-02-23 | Xi'an Libang Medical Technology Co., Ltd | Nanosphere or microsphere drug carrier, preparation method, composition and use thereof |
| CN102348468B (zh) * | 2009-07-31 | 2014-11-05 | 西安力邦医药科技有限责任公司 | 微球药物载体、其制备方法、组合物及应用 |
| WO2012031205A2 (en) * | 2010-09-03 | 2012-03-08 | The Brigham And Women's Hospital, Inc. | Lipid-polymer hybrid particles |
| US9301946B2 (en) * | 2010-12-03 | 2016-04-05 | Warsaw Orthopedic, Inc. | Clonidine and GABA compounds in a biodegradable polymer carrier |
| EP2720699B1 (en) * | 2011-06-14 | 2018-05-16 | Hale Biopharma Ventures, Llc | Administration of benzodiazepine |
| CA2849378A1 (en) * | 2011-09-21 | 2013-03-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Nano delivery systems for sirna |
| JP2016501876A (ja) * | 2012-11-30 | 2016-01-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ステロイドの抗痙攣活性 |
| CN103610664B (zh) * | 2013-12-11 | 2015-09-16 | 中国药科大学 | 一种制备卡马西平聚乳酸-羟基乙酸共聚物微胶囊的方法 |
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2015
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| EP3220917A1 (en) | 2017-09-27 |
| EP3220917A4 (en) | 2018-07-25 |
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| AU2015350554A1 (en) | 2017-04-27 |
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| BR112017010430A2 (pt) | 2017-12-26 |
| US20160136179A1 (en) | 2016-05-19 |
| CN107405351A (zh) | 2017-11-28 |
| MX2017006388A (es) | 2017-08-21 |
| EP3220955A4 (en) | 2018-07-25 |
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| WO2016081236A1 (en) | 2016-05-26 |
| AU2015350347A1 (en) | 2017-05-04 |
| CN107206097A (zh) | 2017-09-26 |
| JP2017537881A (ja) | 2017-12-21 |
| CA2967335A1 (en) | 2016-05-26 |
| WO2016081022A1 (en) | 2016-05-26 |
| US20170224621A1 (en) | 2017-08-10 |
| BR112017010428A2 (pt) | 2017-12-26 |
| JP2017533943A (ja) | 2017-11-16 |
| EP3220955A1 (en) | 2017-09-27 |
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