CA2965151A1 - Serpin fusion polypeptides and methods of use thereof - Google Patents
Serpin fusion polypeptides and methods of use thereof Download PDFInfo
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- CA2965151A1 CA2965151A1 CA2965151A CA2965151A CA2965151A1 CA 2965151 A1 CA2965151 A1 CA 2965151A1 CA 2965151 A CA2965151 A CA 2965151A CA 2965151 A CA2965151 A CA 2965151A CA 2965151 A1 CA2965151 A1 CA 2965151A1
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Landscapes
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| US14/524,832 US10400029B2 (en) | 2011-06-28 | 2014-10-27 | Serpin fusion polypeptides and methods of use thereof |
| US14/524,832 | 2014-10-27 | ||
| PCT/US2015/057533 WO2016069574A1 (en) | 2014-10-27 | 2015-10-27 | Serpin fusion polypeptides and methods of use thereof |
Publications (1)
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| CA2965151A1 true CA2965151A1 (en) | 2016-05-06 |
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| JP7731288B2 (ja) * | 2018-10-29 | 2025-08-29 | スピン セラピューティクス， エルエルシー | アルファ－１－アンチトリプシン欠乏症のための組成物及び方法 |
| WO2020097946A1 (zh) * | 2018-11-18 | 2020-05-22 | 杭州博虎生物科技有限公司 | 一种重组人白细胞介素10融合蛋白及其应用 |
| CN112315897A (zh) * | 2020-11-04 | 2021-02-05 | 深圳前海鹰岗生物科技有限公司 | 一种抑制细胞炎症反应释放治疗痛风急性发作的聚合物微针及制备方法 |
| US20240067703A1 (en) * | 2020-12-21 | 2024-02-29 | Macquarie University | Treatment of glaucoma |
| GB202102258D0 (en) | 2021-02-17 | 2021-03-31 | Arecor Ltd | Novel composition |
| US20240139296A1 (en) * | 2021-03-03 | 2024-05-02 | Formycon Ag | Formulations of ace2 fc fusion proteins |
| CN113325181A (zh) * | 2021-04-25 | 2021-08-31 | 苏州市立医院(北区) | 丝氨酸蛋白酶抑制剂在用于脓毒症早期预警的标志物中的应用 |
| CN114874333B (zh) * | 2021-10-18 | 2025-01-24 | 深圳科兴药业有限公司 | 一种生长激素融合蛋白及其应用 |
| EP4526331A1 (en) | 2022-05-16 | 2025-03-26 | Sanofi AATD Inc. | Effective dosage of recombinant serpin-fc fusion protein for use in a method of treating aat deficiency in a subject |
| AU2024219542B1 (en) * | 2023-05-05 | 2024-10-03 | Ashley Maurice Buckle | Novel therapeutic polypeptide |
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| EP1161532A1 (en) * | 1999-03-01 | 2001-12-12 | Human Genome Sciences, Inc. | Human serpin proteins |
| US7317091B2 (en) * | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
| US7217797B2 (en) * | 2002-10-15 | 2007-05-15 | Pdl Biopharma, Inc. | Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis |
| WO2005007681A2 (en) * | 2003-07-18 | 2005-01-27 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
| ES2622522T3 (es) * | 2003-08-26 | 2017-07-06 | The Regents Of The University Of Colorado, A Body Corporate | Inhibidores de la actividad proteasa de serina y su uso en métodos y composiciones para el tratamiento de infecciones bacterianas |
| US8802820B2 (en) * | 2004-11-12 | 2014-08-12 | Xencor, Inc. | Fc variants with altered binding to FcRn |
| WO2006053301A2 (en) * | 2004-11-12 | 2006-05-18 | Xencor, Inc. | Fc variants with altered binding to fcrn |
| EP1910542B1 (en) * | 2005-07-22 | 2009-12-02 | Five Prime Therapeutics, Inc. | Compositions and methods of treating disease with fgfr fusion proteins |
| AU2006280004A1 (en) * | 2005-08-12 | 2007-02-22 | Schering Corporation | MCP1 fusions |
| AU2009262199B2 (en) * | 2008-06-27 | 2012-08-09 | Amgen Inc. | Ang-2 inhibition to treat multiple sclerosis |
| SG172254A1 (en) * | 2008-12-19 | 2011-07-28 | Macrogenics Inc | Covalent diabodies and uses thereof |
| WO2012087746A1 (en) * | 2010-12-23 | 2012-06-28 | Janssen Biotech, Inc. | Active protease-resistant antibody fc mutants |
| JP5926791B2 (ja) * | 2011-03-29 | 2016-05-25 | ロシュ グリクアート アーゲー | 抗体Ｆｃ変種 |
| CA2839622A1 (en) * | 2011-06-28 | 2013-01-03 | Inhibrx Llc | Wap domain fusion polypeptides and methods of use thereof |
| IL312872A (en) * | 2011-06-28 | 2024-07-01 | Inhibrx Inc | Methods for purifying serpin containing fusion proteins |
| AU2013202648B2 (en) * | 2012-01-10 | 2016-05-19 | Konkuk University | Compositions, methods and uses for alpha-1 antitrypsin fusion molecules |
| MX2014015557A (es) * | 2012-06-21 | 2015-02-24 | Univ Indiana Res & Tech Corp | Polipeptidos de fusion de region fc de polipeptido de ligando receptor de incretina y conjugados con función efectora fc alterada. |
| CA2871882A1 (en) * | 2012-06-27 | 2014-01-03 | F. Hoffmann-La Roche Ag | Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof |
| RU2630659C2 (ru) * | 2012-08-02 | 2017-09-11 | Ф. Хоффманн-Ля Рош Аг | СПОСОБ ПОЛУЧЕНИЯ РАСТВОРИМОГО FcR В ВИДЕ Fc-ГИБРИДА С ИНЕРТНОЙ Fc-ОБЛАСТЬЮ ИММУНОГЛОБУЛИНА И ИХ ПРИМЕНЕНИЯ |
| CA3138788A1 (en) * | 2012-12-05 | 2014-06-12 | Sola Biosciences Llc | Protein expression enhancing polypeptides |
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- 2015-10-27 SG SG11201703390SA patent/SG11201703390SA/en unknown
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2017
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|---|---|
| SG11201703390SA (en) | 2017-05-30 |
| MX2017005467A (es) | 2017-11-30 |
| BR112017008525A2 (pt) | 2018-01-30 |
| EP3212290A4 (en) | 2019-01-23 |
| EP3212290A1 (en) | 2017-09-06 |
| AU2021240153A1 (en) | 2021-10-28 |
| CN107206257A (zh) | 2017-09-26 |
| IL308589A (en) | 2024-01-01 |
| RU2017118325A (ru) | 2018-11-29 |
| WO2016069574A1 (en) | 2016-05-06 |
| MX2021012047A (es) | 2021-11-03 |
| KR20170091096A (ko) | 2017-08-08 |
| JP2020180157A (ja) | 2020-11-05 |
| NZ731223A (en) | 2024-12-20 |
| AU2015339507B2 (en) | 2021-07-01 |
| KR20240005109A (ko) | 2024-01-11 |
| SG10201903142RA (en) | 2019-05-30 |
| RU2746550C2 (ru) | 2021-04-15 |
| AU2024203586A1 (en) | 2024-06-20 |
| IL251799B2 (en) | 2024-04-01 |
| CN114316068A (zh) | 2022-04-12 |
| RU2017118325A3 (enrdf_load_stackoverflow) | 2019-03-21 |
| JP6737781B2 (ja) | 2020-08-12 |
| UA127305C2 (uk) | 2023-07-19 |
| AU2015339507A1 (en) | 2017-05-11 |
| JP2017537888A (ja) | 2017-12-21 |
| HK1244460A1 (zh) | 2018-08-10 |
| IL251799A0 (en) | 2017-06-29 |
| IL251799B1 (en) | 2023-12-01 |
| NZ769391A (en) | 2024-12-20 |
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