CA2960655C - Peptide microarrays and novel biomarkers for celiac disease - Google Patents

Peptide microarrays and novel biomarkers for celiac disease Download PDF

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Publication number
CA2960655C
CA2960655C CA2960655A CA2960655A CA2960655C CA 2960655 C CA2960655 C CA 2960655C CA 2960655 A CA2960655 A CA 2960655A CA 2960655 A CA2960655 A CA 2960655A CA 2960655 C CA2960655 C CA 2960655C
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Prior art keywords
array
polypeptide
peptide
seq
features
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CA2960655A
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English (en)
French (fr)
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CA2960655A1 (en
Inventor
John J. Rajasekaran
Vasanth JAYARAMAN
Kang BEI
Tianhao WANG
Karthik Krishna
Hari Krishnan KRISHNAMURTHY
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Vibrant Holdings LLC
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Vibrant Holdings LLC
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Publication of CA2960655A1 publication Critical patent/CA2960655A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/02Nutritional disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/24Immunology or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Rehabilitation Therapy (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2960655A 2014-09-10 2015-09-10 Peptide microarrays and novel biomarkers for celiac disease Active CA2960655C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462048537P 2014-09-10 2014-09-10
US62/048,537 2014-09-10
PCT/US2015/049528 WO2016040703A1 (en) 2014-09-10 2015-09-10 Peptide microarrays and novel biomarkers for celiac disease

Publications (2)

Publication Number Publication Date
CA2960655A1 CA2960655A1 (en) 2016-03-17
CA2960655C true CA2960655C (en) 2024-03-19

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2960655A Active CA2960655C (en) 2014-09-10 2015-09-10 Peptide microarrays and novel biomarkers for celiac disease

Country Status (7)

Country Link
US (2) US10900964B2 (https=)
EP (1) EP3191629A4 (https=)
JP (4) JP6887945B2 (https=)
AU (3) AU2015314934A1 (https=)
CA (1) CA2960655C (https=)
NZ (1) NZ730519A (https=)
WO (1) WO2016040703A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015314934A1 (en) 2014-09-10 2017-04-20 Vibrant Holdings, Llc Peptide microarrays and novel biomarkers for celiac disease
CA3000509C (en) 2015-10-29 2021-07-27 Vibrant Holdings, Llc Methods, tools, and tool assemblies for biomolecular analysis using microarrays
EP3472181A4 (en) * 2016-06-20 2020-05-13 Healthtell Inc. METHOD FOR DIAGNOSIS AND TREATMENT OF AUTOIMMUNE DISEASES
WO2017223116A2 (en) * 2016-06-20 2017-12-28 Healthtell Inc. Methods for differential diagnosis of autoimmune diseases
CN110073217A (zh) 2016-10-04 2019-07-30 豪夫迈·罗氏有限公司 用于鉴定合成分类器的系统和方法
US11371990B2 (en) 2016-11-11 2022-06-28 Cowper Sciences Inc. Methods for identifying candidate biomarkers
CN107176974B (zh) * 2017-06-06 2021-04-13 中国医学科学院北京协和医院 ω-5-醇溶蛋白特异的CD4+T细胞表位及其应用
EP3735481A4 (en) * 2018-01-05 2021-08-11 Centrillion Technology Holdings Corporation METHODS OF MANUFACTURING A HIGH RESOLUTION DNA CHIP AND USING THE SAME IN SEQUENCING
WO2020076859A1 (en) * 2018-10-08 2020-04-16 Vibrant Holdings, Llc tTG-DGP BIOMARKERS FOR MONITORING CELIAC DISEASE
GB202002010D0 (en) * 2020-02-13 2020-04-01 Univ Of Nottingham Research Microtopographies and uses thereof
CN111926051A (zh) * 2020-07-10 2020-11-13 内蒙古燕谷坊全谷物产业发展有限责任公司 一种燕麦肽粉及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19630557C2 (de) * 1996-07-18 1998-07-02 Schuppan Detlef Priv Doz Dr Dr Verfahren zum Nachweis von Antikörpern aus Körperflüssigkeiten durch eine Immunreaktion mit Gewebe-Transglutaminase (tTG) sowie die Verwendung von tTG in Diagnose und Therapie
EP1197755A1 (en) * 2000-10-11 2002-04-17 Pepscan Systems B.V. Identification of protein binding sites
WO2002047075A2 (en) 2000-11-13 2002-06-13 Picoliter Inc. Integrated device with surface-attached molecular moieties and related machine-readable information
JP2002320341A (ja) 2001-02-14 2002-10-31 Sony Corp 充放電装置および方法、電力供給装置および方法、電力供給システムおよび方法、プログラム格納媒体、並びにプログラム
EP1451584B1 (en) 2001-11-09 2011-05-11 3dbiosurfaces Technologies, LLC High surface area substrates for microarrays and methods to make same
GB0212885D0 (en) * 2002-06-05 2002-07-17 Isis Innovation Therapeutic epitopes and uses thereof
US7290169B2 (en) 2004-04-06 2007-10-30 Hewlett-Packard Development Company, L.P. Core-level processor lockstepping
AU2009276704B2 (en) 2008-07-28 2015-01-22 Children's Medical Center Corporation Prominin-1 peptide fragments and uses thereof
CN102438643B (zh) 2008-11-30 2015-07-01 免疫桑特公司 用于治疗乳糜泻的组合物和方法
FR2949782B1 (fr) 2009-09-04 2015-10-16 Isp Investments Inc Peptide activateur de la transglutaminase et composition cosmetique ou pharmaceutique le contenant.
JP6012767B2 (ja) * 2012-02-07 2016-10-25 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー 基板、ペプチドアレイ、および方法
DE102013214247A1 (de) 2013-07-22 2015-01-22 Bayerische Motoren Werke Aktiengesellschaft Blindnietmutter für die Verbindung zweier Bauteile
CN103675291A (zh) 2013-11-25 2014-03-26 南昌大学 一种基于t细胞表位筛查低乳糜泻毒性小麦品种的方法
AU2015314934A1 (en) 2014-09-10 2017-04-20 Vibrant Holdings, Llc Peptide microarrays and novel biomarkers for celiac disease

Also Published As

Publication number Publication date
JP2021144040A (ja) 2021-09-24
JP7256229B2 (ja) 2023-04-11
WO2016040703A1 (en) 2016-03-17
EP3191629A1 (en) 2017-07-19
JP6887945B2 (ja) 2021-06-16
JP2023093494A (ja) 2023-07-04
JP7781813B2 (ja) 2025-12-08
AU2019200921B2 (en) 2021-07-01
JP2017532544A (ja) 2017-11-02
AU2015314934A1 (en) 2017-04-20
NZ730519A (en) 2018-10-26
US10900964B2 (en) 2021-01-26
EP3191629A4 (en) 2018-07-11
US20210285948A1 (en) 2021-09-16
US20170269077A1 (en) 2017-09-21
CA2960655A1 (en) 2016-03-17
AU2019200921A1 (en) 2019-03-07
JP2026035691A (ja) 2026-03-04
NZ742911A (en) 2024-02-23
AU2021203987A1 (en) 2021-07-08

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