CA2957783C - Polymers and conjugates comprising the same - Google Patents

Polymers and conjugates comprising the same Download PDF

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Publication number
CA2957783C
CA2957783C CA2957783A CA2957783A CA2957783C CA 2957783 C CA2957783 C CA 2957783C CA 2957783 A CA2957783 A CA 2957783A CA 2957783 A CA2957783 A CA 2957783A CA 2957783 C CA2957783 C CA 2957783C
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Canada
Prior art keywords
antibody
group
polymer
label
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2957783A
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English (en)
French (fr)
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CA2957783A1 (en
Inventor
Lei Tang
Wenjun Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ventana Medical Systems Inc
Original Assignee
Ventana Medical Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Medical Systems Inc filed Critical Ventana Medical Systems Inc
Priority to CA3185265A priority Critical patent/CA3185265A1/en
Publication of CA2957783A1 publication Critical patent/CA2957783A1/en
Application granted granted Critical
Publication of CA2957783C publication Critical patent/CA2957783C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/10Oligonucleotides as tagging agents for labelling antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
CA2957783A 2014-10-02 2015-10-01 Polymers and conjugates comprising the same Active CA2957783C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3185265A CA3185265A1 (en) 2014-10-02 2015-10-01 Polymers and conjugates comprising the same

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462059073P 2014-10-02 2014-10-02
US62/059,073 2014-10-02
US201562212879P 2015-09-01 2015-09-01
US62/212,879 2015-09-01
PCT/EP2015/072701 WO2016050913A2 (en) 2014-10-02 2015-10-01 Polymers and conjugates comprising the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3185265A Division CA3185265A1 (en) 2014-10-02 2015-10-01 Polymers and conjugates comprising the same

Publications (2)

Publication Number Publication Date
CA2957783A1 CA2957783A1 (en) 2016-04-07
CA2957783C true CA2957783C (en) 2023-02-28

Family

ID=54266549

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2957783A Active CA2957783C (en) 2014-10-02 2015-10-01 Polymers and conjugates comprising the same
CA3185265A Pending CA3185265A1 (en) 2014-10-02 2015-10-01 Polymers and conjugates comprising the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3185265A Pending CA3185265A1 (en) 2014-10-02 2015-10-01 Polymers and conjugates comprising the same

Country Status (6)

Country Link
US (3) US11079372B2 (https=)
EP (1) EP3201628B1 (https=)
JP (1) JP6762296B2 (https=)
AU (1) AU2015326827B2 (https=)
CA (2) CA2957783C (https=)
WO (1) WO2016050913A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017141903A1 (ja) * 2016-02-16 2017-08-24 株式会社トッパンTomoegawaオプティカルフィルム 光学積層体、偏光板及び表示装置
CN114761431B (zh) * 2019-10-16 2025-04-25 株式会社Lg化学 新生儿Fc受体结合AFFIMER

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US1564604A (en) 1925-06-12 1925-12-08 Chas S Hodges Water wheel
US4824775A (en) * 1985-01-03 1989-04-25 Molecular Diagnostics, Inc. Cells labeled with multiple Fluorophores bound to a nucleic acid carrier
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US5641629A (en) * 1990-06-11 1997-06-24 Nexstar Pharmacueticals Inc Spectroscopically detectable nucleic acid ligands
DE4302459A1 (de) * 1993-01-29 1994-08-04 Bayer Ag Sulfocumarinhaltige Nukleotide und deren Verwendung in Nachweisverfahren für Nukleinsäuren
AU6514096A (en) * 1995-07-27 1997-02-26 Carsten Behrens A new achiral linker reagent for the incorporation of multiple amino groups into oligonucleotides
WO1999043287A2 (en) * 1998-02-25 1999-09-02 Biotraces, Inc. Phosphate-based dendrimers for bioassays
JP3847559B2 (ja) 1998-02-27 2006-11-22 ベンタナ・メデイカル・システムズ・インコーポレーテツド 独立スライド加熱器を有する自動化分子病理学装置
US6582962B1 (en) 1998-02-27 2003-06-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US20030211630A1 (en) 1998-02-27 2003-11-13 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US6372937B1 (en) 1998-11-09 2002-04-16 Mark Norman Bobrow Enhanced catalyzed reporter deposition
FR2791141B1 (fr) * 1999-03-15 2001-06-01 Cis Bio Int Procede de reduction de l'extinction de fluorescence due au milieu de mesure
US6670113B2 (en) 2001-03-30 2003-12-30 Nanoprobes Enzymatic deposition and alteration of metals
WO2002082083A1 (en) * 2001-04-04 2002-10-17 Wako Pure Chemical Industries, Ltd. Electrophoresis
US7514551B2 (en) 2003-04-03 2009-04-07 Enzo Life Sciences, Inc. Multisignal labeling reagents, and processes and uses therefor
DK1636586T3 (da) 2003-06-24 2009-11-23 Ventana Med Syst Inc Enzymkatalyseret metaldeponering til foröget in situ-detektion af immunhistokemisker epitoper og nucleinsyresekvenser
DE10340143A1 (de) 2003-08-26 2005-03-31 SSI Schäfer PEEM GmbH Kommissionierplatz und Verfahren zum Kommissionieren
EP1725572B1 (de) * 2003-11-05 2017-05-31 AGCT GmbH Makromolekulare nukleotidverbindungen und methoden zu deren anwendung
JP2008082784A (ja) * 2006-09-26 2008-04-10 Sysmex Corp 新規な標的物質検出用試薬
DK2444807T3 (da) * 2006-11-01 2014-08-11 Ventana Med Syst Inc Mono- og dinitropyrazolhaptenkonjugater
GB0701444D0 (en) * 2007-01-25 2007-03-07 Iti Scotland Ltd Detecting analytes
EP2167963B1 (en) * 2007-05-23 2019-04-17 Ventana Medical Systems, Inc. Polymeric carriers for immunohistochemistry and in situ hybridization
KR101072900B1 (ko) * 2007-12-04 2011-10-17 주식회사 파나진 고정화된 펩티드핵산 프로브를 사용한 표적핵산의 선택적 표지 및 검출 방법
KR101289164B1 (ko) * 2008-03-10 2013-07-31 퀜티백트 에이/에스 삼중나선구조 형성 단량체 단위를 포함하는 프라이머를 이용한 표적증폭 및 서열분석
FR2933520B1 (fr) 2008-07-04 2011-02-11 Canon Kk Procede et dispositif de restauration d'une sequence video
EP2334827B1 (en) 2008-08-22 2015-03-11 Ventana Medical Systems, Inc. Method for chromogenic detection of two or more target molecules in a single sample
DE102008062372B3 (de) * 2008-12-17 2010-06-17 Medizinische Hochschule Hannover Nachweiskonjugat und Verfahren zur Analyse
CA2842661C (en) 2009-10-19 2016-02-23 Ventana Medical Systems, Inc. Imaging system and techniques
EP2807272A1 (en) * 2012-01-27 2014-12-03 Ventana Medical Systems, Inc. Devices and methods for detecting bio-analytes using optically decipherable patterns
ES2678211T3 (es) 2012-03-27 2018-08-09 Ventana Medical Systems, Inc. Conjugados de señalización y procedimientos de uso
JP5509440B2 (ja) * 2012-06-22 2014-06-04 国立大学法人九州大学 タンパク質−核酸複合体の製造方法および標的物の検出方法
CA2940111C (en) * 2014-02-21 2022-03-15 Ventana Medical Systems, Inc. Single-stranded oligonucleotide probes for chromosome or gene copy enumeration

Also Published As

Publication number Publication date
JP6762296B2 (ja) 2020-09-30
US20210325376A1 (en) 2021-10-21
JP2017531797A (ja) 2017-10-26
US20260056191A1 (en) 2026-02-26
EP3201628B1 (en) 2020-11-18
US20170205399A1 (en) 2017-07-20
EP3201628A2 (en) 2017-08-09
US11079372B2 (en) 2021-08-03
US12553886B2 (en) 2026-02-17
WO2016050913A2 (en) 2016-04-07
WO2016050913A3 (en) 2016-05-26
CA2957783A1 (en) 2016-04-07
CA3185265A1 (en) 2016-04-07
AU2015326827A1 (en) 2017-02-23
AU2015326827B2 (en) 2019-11-07

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