CA2943951C - Genetic markers for antipsychotic induced weight gain and methods for use thereof - Google Patents

Genetic markers for antipsychotic induced weight gain and methods for use thereof Download PDF

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Publication number
CA2943951C
CA2943951C CA2943951A CA2943951A CA2943951C CA 2943951 C CA2943951 C CA 2943951C CA 2943951 A CA2943951 A CA 2943951A CA 2943951 A CA2943951 A CA 2943951A CA 2943951 C CA2943951 C CA 2943951C
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seq
subject
polymorphisms
weight gain
allele
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CA2943951A
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English (en)
French (fr)
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CA2943951A1 (en
Inventor
Clement C. Zai
James L. Kennedy
Daniel J. Mueller
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Centre for Addiction and Mental Health
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Centre for Addiction and Mental Health
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2943951A 2013-10-17 2014-10-17 Genetic markers for antipsychotic induced weight gain and methods for use thereof Active CA2943951C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361892094P 2013-10-17 2013-10-17
US61/892,094 2013-10-17
PCT/CA2014/051000 WO2015054792A1 (en) 2013-10-17 2014-10-17 Genetic markers for antipsychotic induced weight gain and methods for use thereof

Publications (2)

Publication Number Publication Date
CA2943951A1 CA2943951A1 (en) 2015-04-23
CA2943951C true CA2943951C (en) 2022-05-31

Family

ID=52827506

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2943951A Active CA2943951C (en) 2013-10-17 2014-10-17 Genetic markers for antipsychotic induced weight gain and methods for use thereof

Country Status (12)

Country Link
US (1) US10301678B2 (enExample)
EP (2) EP3058106B1 (enExample)
JP (1) JP6524073B2 (enExample)
KR (1) KR102252926B1 (enExample)
CN (1) CN106029901A (enExample)
AU (1) AU2014336928B2 (enExample)
CA (1) CA2943951C (enExample)
ES (1) ES2728072T3 (enExample)
IL (1) IL245159B (enExample)
PT (1) PT3058106T (enExample)
SG (1) SG11201602998QA (enExample)
WO (1) WO2015054792A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3749961A1 (en) * 2018-02-09 2020-12-16 Metabolomic Diagnostics Limited Methods of predicting pre term birth from preeclampsia using metabolic and protein biomarkers
CN110317868B (zh) * 2019-08-09 2020-05-19 新疆医科大学第二附属医院 一种基于多基因组合交互作用预测二代抗精神病药物治疗精神分裂症致体重增加分析方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
CA2176348C (en) 1993-11-12 2004-11-02 Sanjay Tyagi Hybridization probes for nucleic acid detection, universal stems, methods and kits
US20030108938A1 (en) * 2001-11-06 2003-06-12 David Pickar Pharmacogenomics-based clinical trial design recommendation and management system and method
US8012718B2 (en) 2006-03-31 2011-09-06 Genomas, Inc. Physiogenomic method for predicting diabetes and metabolic syndromes induced by psychotropic drugs
US20070292962A1 (en) * 2006-04-10 2007-12-20 Duke University Methods and compositions for genetic markers for autism
US7795033B2 (en) 2007-03-19 2010-09-14 The United States Of America As Represented By The Department Of Health And Human Services Methods to predict the outcome of treatment with antidepressant medication
US8476012B2 (en) 2008-04-18 2013-07-02 Genomas, Inc. Physiogenomic method for predicting metabolic and cardiovascular side effects of thiazolidinediones
US8355927B2 (en) 2010-11-05 2013-01-15 Genomind, Llc Neuropsychiatric test reports
CN104114714A (zh) 2011-12-14 2014-10-22 阿斯利康(瑞典)有限公司 Gabr-a2诊断

Also Published As

Publication number Publication date
JP2016534715A (ja) 2016-11-10
PT3058106T (pt) 2019-05-30
SG11201602998QA (en) 2016-05-30
ES2728072T3 (es) 2019-10-22
KR102252926B1 (ko) 2021-05-20
AU2014336928B2 (en) 2020-07-16
CA2943951A1 (en) 2015-04-23
IL245159B (en) 2020-10-29
WO2015054792A1 (en) 2015-04-23
KR20160098188A (ko) 2016-08-18
EP3058106B1 (en) 2019-02-27
US10301678B2 (en) 2019-05-28
IL245159A0 (en) 2016-06-30
EP3561076A1 (en) 2019-10-30
EP3058106A1 (en) 2016-08-24
EP3058106A4 (en) 2017-06-07
JP6524073B2 (ja) 2019-06-05
US20160237499A1 (en) 2016-08-18
CN106029901A (zh) 2016-10-12

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