JP6524073B2 - 抗精神病薬誘導体重増加に関連する遺伝子マーカーおよびその使用のための方法 - Google Patents

抗精神病薬誘導体重増加に関連する遺伝子マーカーおよびその使用のための方法 Download PDF

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JP6524073B2
JP6524073B2 JP2016524143A JP2016524143A JP6524073B2 JP 6524073 B2 JP6524073 B2 JP 6524073B2 JP 2016524143 A JP2016524143 A JP 2016524143A JP 2016524143 A JP2016524143 A JP 2016524143A JP 6524073 B2 JP6524073 B2 JP 6524073B2
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weight gain
polymorphisms
antipsychotic
seq
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JP2016534715A (ja
JP2016534715A5 (enExample
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ザイ,クレメント・シー
ケネディ,ジェームズ・エル
ミューラー,ダニエル・ジェイ
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Centre for Addiction and Mental Health
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016524143A 2013-10-17 2014-10-17 抗精神病薬誘導体重増加に関連する遺伝子マーカーおよびその使用のための方法 Expired - Fee Related JP6524073B2 (ja)

Applications Claiming Priority (3)

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US201361892094P 2013-10-17 2013-10-17
US61/892,094 2013-10-17
PCT/CA2014/051000 WO2015054792A1 (en) 2013-10-17 2014-10-17 Genetic markers for antipsychotic induced weight gain and methods for use thereof

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JP2016534715A JP2016534715A (ja) 2016-11-10
JP2016534715A5 JP2016534715A5 (enExample) 2017-11-24
JP6524073B2 true JP6524073B2 (ja) 2019-06-05

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JP2016524143A Expired - Fee Related JP6524073B2 (ja) 2013-10-17 2014-10-17 抗精神病薬誘導体重増加に関連する遺伝子マーカーおよびその使用のための方法

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US (1) US10301678B2 (enExample)
EP (2) EP3058106B1 (enExample)
JP (1) JP6524073B2 (enExample)
KR (1) KR102252926B1 (enExample)
CN (1) CN106029901A (enExample)
AU (1) AU2014336928B2 (enExample)
CA (1) CA2943951C (enExample)
ES (1) ES2728072T3 (enExample)
IL (1) IL245159B (enExample)
PT (1) PT3058106T (enExample)
SG (1) SG11201602998QA (enExample)
WO (1) WO2015054792A1 (enExample)

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Publication number Priority date Publication date Assignee Title
EP3749961A1 (en) * 2018-02-09 2020-12-16 Metabolomic Diagnostics Limited Methods of predicting pre term birth from preeclampsia using metabolic and protein biomarkers
CN110317868B (zh) * 2019-08-09 2020-05-19 新疆医科大学第二附属医院 一种基于多基因组合交互作用预测二代抗精神病药物治疗精神分裂症致体重增加分析方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
CA2176348C (en) 1993-11-12 2004-11-02 Sanjay Tyagi Hybridization probes for nucleic acid detection, universal stems, methods and kits
US20030108938A1 (en) * 2001-11-06 2003-06-12 David Pickar Pharmacogenomics-based clinical trial design recommendation and management system and method
US8012718B2 (en) 2006-03-31 2011-09-06 Genomas, Inc. Physiogenomic method for predicting diabetes and metabolic syndromes induced by psychotropic drugs
US20070292962A1 (en) * 2006-04-10 2007-12-20 Duke University Methods and compositions for genetic markers for autism
US7795033B2 (en) 2007-03-19 2010-09-14 The United States Of America As Represented By The Department Of Health And Human Services Methods to predict the outcome of treatment with antidepressant medication
US8476012B2 (en) 2008-04-18 2013-07-02 Genomas, Inc. Physiogenomic method for predicting metabolic and cardiovascular side effects of thiazolidinediones
US8355927B2 (en) 2010-11-05 2013-01-15 Genomind, Llc Neuropsychiatric test reports
CN104114714A (zh) 2011-12-14 2014-10-22 阿斯利康(瑞典)有限公司 Gabr-a2诊断

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JP2016534715A (ja) 2016-11-10
PT3058106T (pt) 2019-05-30
SG11201602998QA (en) 2016-05-30
ES2728072T3 (es) 2019-10-22
KR102252926B1 (ko) 2021-05-20
AU2014336928B2 (en) 2020-07-16
CA2943951A1 (en) 2015-04-23
IL245159B (en) 2020-10-29
WO2015054792A1 (en) 2015-04-23
CA2943951C (en) 2022-05-31
KR20160098188A (ko) 2016-08-18
EP3058106B1 (en) 2019-02-27
US10301678B2 (en) 2019-05-28
IL245159A0 (en) 2016-06-30
EP3561076A1 (en) 2019-10-30
EP3058106A1 (en) 2016-08-24
EP3058106A4 (en) 2017-06-07
US20160237499A1 (en) 2016-08-18
CN106029901A (zh) 2016-10-12

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