CA2936283C - Compositions and methods for treatment of abnormal cell growth - Google Patents
Compositions and methods for treatment of abnormal cell growth Download PDFInfo
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- CA2936283C CA2936283C CA2936283A CA2936283A CA2936283C CA 2936283 C CA2936283 C CA 2936283C CA 2936283 A CA2936283 A CA 2936283A CA 2936283 A CA2936283 A CA 2936283A CA 2936283 C CA2936283 C CA 2936283C
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- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
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- Pulmonology (AREA)
- Reproductive Health (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461925467P | 2014-01-09 | 2014-01-09 | |
| US61/925,467 | 2014-01-09 | ||
| PCT/US2015/010810 WO2015106096A1 (en) | 2014-01-09 | 2015-01-09 | Compositions and methods for treatment of abnormal cell growth |
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| CA2936283A1 CA2936283A1 (en) | 2015-07-16 |
| CA2936283C true CA2936283C (en) | 2023-02-28 |
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| CA2936283A Active CA2936283C (en) | 2014-01-09 | 2015-01-09 | Compositions and methods for treatment of abnormal cell growth |
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| EP3795157A4 (en) * | 2018-05-15 | 2022-03-23 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | Pharmaceutical composition comprising small molecule egfr inhibitor and preparation method therefor |
| JP2022547358A (ja) * | 2019-09-13 | 2022-11-14 | ジ インスティテュート オブ キャンサー リサーチ：ロイヤル キャンサー ホスピタル | 治療組成物、組み合わせ、及び使用方法 |
| WO2021191812A1 (en) * | 2020-03-27 | 2021-09-30 | Pfizer Inc. | Treatment of type 2 diabetes or obesity or overweight with 2-[(4-{6-[(4-cyano-2-fluorobenzyl)oxy]pyridin-2-yl} piperidin-1-yl)methyl]-1-[(2s)-oxetan-2-ylmethyl]-1h-benzimidazole-6-carboxylic acid or a pharmaceutically salt thereof |
| SI3965742T1 (sl) * | 2020-04-24 | 2023-10-30 | Dr. Falk Pharma Gmbh | Sistemska formulacija piridinonskega derivata za bolezni, povezane s tg2 |
| US11873296B2 (en) | 2022-06-07 | 2024-01-16 | Verastem, Inc. | Solid forms of a dual RAF/MEK inhibitor |
| CN117582504A (zh) * | 2022-08-15 | 2024-02-23 | 海创药业股份有限公司 | 一种治疗卵巢癌的联合用药物 |
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| DE69837903T2 (de) * | 1997-08-11 | 2008-02-14 | Pfizer Products Inc., Groton | Feste pharmazeutische Dispersionen mit erhöhter Bioverfügbarkeit |
| CA2534371A1 (en) * | 2003-08-04 | 2005-02-10 | Pfizer Products Inc. | Dosage forms providing controlled release of cholesteryl ester transfer protein inhibitors and immediate release of hmg-coa reductase inhibitors |
| WO2006061712A2 (en) * | 2004-12-10 | 2006-06-15 | Pfizer Inc. | Use of mek inhibitors in treating abnormal cell growth |
| JP4782239B2 (ja) * | 2007-04-18 | 2011-09-28 | ファイザー・プロダクツ・インク | 異常細胞増殖治療のためのスルホニルアミド誘導体 |
| HUE035931T2 (hu) * | 2008-08-13 | 2018-06-28 | Vertex Pharma | N-[2,4-bis(1,1-dimetiletil)-5-hidroxipenil]-1,4-dihidro-4-oxokinolin-3-karboxamid gyógyszerészeti készítménye és annak alkalmazása |
| WO2011112922A2 (en) * | 2010-03-11 | 2011-09-15 | Vertex Pharmaceuticals Incorporated | Co-crystals and pharmaceutical formulations comprising the same |
| AU2011293658B2 (en) * | 2010-08-23 | 2015-03-05 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxy propyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide and administration thereof |
| CN103491964A (zh) * | 2011-03-08 | 2014-01-01 | 扎里卡斯药品有限公司 | 固体分散体制剂及其使用方法 |
| EP2572731A1 (en) * | 2011-09-26 | 2013-03-27 | Abbott GmbH & Co. KG | Formulations based on solid dispersions |
| ES2945387T3 (es) * | 2014-02-07 | 2023-06-30 | Verastem Inc | Procedimientos y composiciones para tratar el crecimiento celular anormal |
| AU2016286091B2 (en) * | 2015-06-29 | 2021-02-04 | Verastem, Inc. | Therapeutic compositions, combinations, and methods of use |
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2015
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- 2015-01-09 NZ NZ721934A patent/NZ721934A/en unknown
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- 2015-01-09 AU AU2015204597A patent/AU2015204597B2/en active Active
- 2015-01-09 US US14/593,468 patent/US20150190346A1/en not_active Abandoned
- 2015-01-09 CA CA2936283A patent/CA2936283C/en active Active
- 2015-01-09 NZ NZ760233A patent/NZ760233A/en unknown
- 2015-01-09 ES ES15701875T patent/ES2870562T3/es active Active
- 2015-01-09 MX MX2016009056A patent/MX384259B/es unknown
- 2015-01-09 KR KR1020167021370A patent/KR102444494B1/ko active Active
- 2015-01-09 EP EP21160977.1A patent/EP3900726A1/en active Pending
- 2015-01-09 CN CN201580011527.7A patent/CN106102744A/zh active Pending
- 2015-01-09 KR KR1020247035735A patent/KR20240159639A/ko active Pending
- 2015-01-09 SG SG11201605588YA patent/SG11201605588YA/en unknown
- 2015-01-09 BR BR112016016021-5A patent/BR112016016021B1/pt active IP Right Grant
- 2015-01-09 WO PCT/US2015/010810 patent/WO2015106096A1/en not_active Ceased
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- 2015-01-09 EP EP15701875.5A patent/EP3091981B1/en active Active
- 2015-01-09 KR KR1020227031505A patent/KR20220130251A/ko not_active Ceased
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2016
- 2016-07-07 IL IL246667A patent/IL246667B/en unknown
- 2016-07-08 MX MX2021008225A patent/MX2021008225A/es unknown
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2019
- 2019-03-11 US US16/298,907 patent/US20200038331A1/en not_active Abandoned
- 2019-09-17 JP JP2019168245A patent/JP2020007355A/ja active Pending
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2020
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2021
- 2021-10-05 JP JP2021163957A patent/JP2022001587A/ja not_active Withdrawn
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2022
- 2022-04-07 IL IL292054A patent/IL292054A/en unknown
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2023
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2025
- 2025-02-28 JP JP2025031469A patent/JP2025084892A/ja active Pending
- 2025-06-26 AU AU2025204843A patent/AU2025204843A1/en active Pending
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