CA2928639A1 - Mise en suspension et agregation de cellules souches pluripotentes humaines aux fins de differenciation en cellules endocrines du pancreas - Google Patents

Mise en suspension et agregation de cellules souches pluripotentes humaines aux fins de differenciation en cellules endocrines du pancreas Download PDF

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Publication number
CA2928639A1
CA2928639A1 CA2928639A CA2928639A CA2928639A1 CA 2928639 A1 CA2928639 A1 CA 2928639A1 CA 2928639 A CA2928639 A CA 2928639A CA 2928639 A CA2928639 A CA 2928639A CA 2928639 A1 CA2928639 A1 CA 2928639A1
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Canada
Prior art keywords
cells
cell
differentiation
stage
pluripotent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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CA2928639A
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English (en)
Inventor
Benjamin Fryer
Daina LANIAUSKAS
Marcia BLACKMOORE
Haiyun Wang
Kostadinka LILOVA
Shelley Nelson
Elizabeth ROSOCHA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/998,974 external-priority patent/US10377989B2/en
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of CA2928639A1 publication Critical patent/CA2928639A1/fr
Abandoned legal-status Critical Current

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/19—Growth and differentiation factors [GDF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2928639A 2013-11-01 2014-05-21 Mise en suspension et agregation de cellules souches pluripotentes humaines aux fins de differenciation en cellules endocrines du pancreas Abandoned CA2928639A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361962158P 2013-11-01 2013-11-01
US61/962,158 2013-11-01
US13/998,974 US10377989B2 (en) 2012-12-31 2013-12-30 Methods for suspension cultures of human pluripotent stem cells
US13/998,974 2013-12-30
PCT/US2014/038993 WO2015065524A2 (fr) 2013-11-01 2014-05-21 Mise en suspension et agrégation de cellules souches pluripotentes humaines aux fins de différenciation en cellules endocrines du pancréas

Publications (1)

Publication Number Publication Date
CA2928639A1 true CA2928639A1 (fr) 2015-05-07

Family

ID=53004904

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2928639A Abandoned CA2928639A1 (fr) 2013-11-01 2014-05-21 Mise en suspension et agregation de cellules souches pluripotentes humaines aux fins de differenciation en cellules endocrines du pancreas
CA2928741A Abandoned CA2928741A1 (fr) 2013-11-01 2014-06-17 Mise en suspension et regroupement de cellules souches pluripotentes humaines pour la differenciation en cellules endocrines pancreatiques

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2928741A Abandoned CA2928741A1 (fr) 2013-11-01 2014-06-17 Mise en suspension et regroupement de cellules souches pluripotentes humaines pour la differenciation en cellules endocrines pancreatiques

Country Status (12)

Country Link
EP (2) EP3063268A4 (fr)
JP (2) JP2016534731A (fr)
KR (4) KR20160079072A (fr)
CN (2) CN105793413A (fr)
AU (4) AU2014342995C1 (fr)
BR (1) BR112016009393A8 (fr)
CA (2) CA2928639A1 (fr)
MX (2) MX2016005657A (fr)
PH (2) PH12016500783A1 (fr)
RU (2) RU2689710C2 (fr)
SG (2) SG11201603045VA (fr)
WO (2) WO2015065524A2 (fr)

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WO2017223233A1 (fr) * 2016-06-23 2017-12-28 Tithon Biotech, Inc. Cellules exprimant le récepteur d'hormone parathyroïde 1 et leurs utilisations
SG11201903428XA (en) * 2016-11-16 2019-05-30 Cynata Therapeutics Ltd Pluripotent stem cell assay
US10391156B2 (en) 2017-07-12 2019-08-27 Viacyte, Inc. University donor cells and related methods
EP3654996A4 (fr) * 2017-07-21 2021-03-24 Semma Therapeutics, Inc. Réagrégation de cellules bêta pancréatiques dérivées de cellules souches
JP7000896B2 (ja) * 2017-08-23 2022-01-19 王子ホールディングス株式会社 細胞シート形成部材、細胞シート形成部材の製造方法、および、細胞シートの製造方法
AU2019205942A1 (en) * 2018-01-05 2020-08-13 Platelet Biogenesis, Inc. Compositions and methods for producing megakaryocytes
JP2021510527A (ja) * 2018-01-18 2021-04-30 エージェンシー フォー サイエンス， テクノロジー アンド リサーチ 懸濁培養におけるヒト多能性幹細胞系の分化のための方法
KR102115360B1 (ko) * 2018-05-30 2020-05-26 주식회사 바이블리오테카 성체 줄기세포 배양액 및 그 제조방법
US20200080107A1 (en) 2018-09-07 2020-03-12 Crispr Therapeutics Ag Universal donor cells
WO2020243668A1 (fr) 2019-05-31 2020-12-03 W. L. Gore & Associates, Inc. Dispositifs d'encapsulation de cellules présentant des distances de diffusion d'oxygène régulées
JP2022534545A (ja) 2019-05-31 2022-08-01 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 生体適合性メンブレン複合体
EP3975926A1 (fr) 2019-05-31 2022-04-06 W.L. Gore & Associates, Inc. Composite à membrane biocompatible
CA3139591C (fr) 2019-05-31 2024-01-16 Timothy M. BRUHN Composite a membrane biocompatible
CN114364791A (zh) 2019-09-05 2022-04-15 克里斯珀医疗股份公司 通用供体细胞
US11104918B2 (en) 2019-09-05 2021-08-31 Crispr Therapeutics Ag Universal donor cells
CN114729323A (zh) * 2019-11-22 2022-07-08 诺和诺德股份有限公司 旋转聚集的神经微球及其应用
CA3203392A1 (fr) 2020-12-31 2022-07-07 Alireza Rezania Cellules donneuses universelles
WO2022203051A1 (fr) * 2021-03-25 2022-09-29 株式会社カネカ Procédé de production d'une population de cellules souches pluripotentes

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JP2005533480A (ja) * 2001-11-09 2005-11-10 アーテセル・サイエンシズ・インコーポレーテツド 脂肪組織由来間質細胞の膵内分泌分化およびその使用
DK2733203T3 (en) * 2006-08-02 2019-02-04 Technion Res & Dev Foundation PROCEDURES FOR EXPANSION OF EMBRYONAL STEM CELLS IN A SUSPENSION CULTURE
WO2008056779A1 (fr) * 2006-11-09 2008-05-15 Japan As Represented By The President Of International Medical Center Of Japan Procédé destiné à la culture et au passage d'une cellule souche embryonnaire de primate, et procédé destiné à induire la différenciation de la cellule souche embryonnaire
US20090053182A1 (en) * 2007-05-25 2009-02-26 Medistem Laboratories, Inc. Endometrial stem cells and methods of making and using same
EP2559756B1 (fr) * 2007-07-01 2019-12-18 Janssen Biotech, Inc. Culture de cellules souches pluripotentes uniques
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AU2014343007A1 (en) 2016-05-05
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AU2014342995C1 (en) 2018-08-09
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