CA2927357A1 - Chitosan paste wound dressing - Google Patents
Chitosan paste wound dressing Download PDFInfo
- Publication number
- CA2927357A1 CA2927357A1 CA2927357A CA2927357A CA2927357A1 CA 2927357 A1 CA2927357 A1 CA 2927357A1 CA 2927357 A CA2927357 A CA 2927357A CA 2927357 A CA2927357 A CA 2927357A CA 2927357 A1 CA2927357 A1 CA 2927357A1
- Authority
- CA
- Canada
- Prior art keywords
- paste
- phosphate
- kit according
- water
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229920001661 Chitosan Polymers 0.000 title claims abstract description 69
- 239000000203 mixture Substances 0.000 claims abstract description 65
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 53
- 206010052428 Wound Diseases 0.000 claims abstract description 52
- 229910019142 PO4 Inorganic materials 0.000 claims abstract description 33
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims abstract description 32
- 239000010452 phosphate Substances 0.000 claims abstract description 32
- 239000000243 solution Substances 0.000 claims description 36
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 33
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 claims description 26
- 239000002953 phosphate buffered saline Substances 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 25
- 230000001954 sterilising effect Effects 0.000 claims description 14
- 238000004659 sterilization and disinfection Methods 0.000 claims description 14
- 239000000314 lubricant Substances 0.000 claims description 11
- 231100000135 cytotoxicity Toxicity 0.000 claims description 10
- 239000000080 wetting agent Substances 0.000 claims description 10
- 230000003013 cytotoxicity Effects 0.000 claims description 8
- 238000010894 electron beam technology Methods 0.000 claims description 6
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- 238000009864 tensile test Methods 0.000 claims description 4
- XYZZKVRWGOWVGO-UHFFFAOYSA-N Glycerol-phosphate Chemical compound OP(O)(O)=O.OCC(O)CO XYZZKVRWGOWVGO-UHFFFAOYSA-N 0.000 claims description 3
- 230000005855 radiation Effects 0.000 claims description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical class Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 2
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| US14/061,993 | 2013-10-24 | ||
| US14/319,901 US9192574B2 (en) | 2013-10-24 | 2014-06-30 | Chitosan paste wound dressing |
| US14/319,901 | 2014-06-30 | ||
| PCT/US2014/062041 WO2015061612A1 (en) | 2013-10-24 | 2014-10-23 | Chitosan paste wound dressing |
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| US8932560B2 (en) | 2007-09-04 | 2015-01-13 | University of Maryland, College Parke | Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells |
| US8668899B2 (en) | 2009-11-13 | 2014-03-11 | University Of Maryland, College Park | Advanced functional biocompatible foam used as a hemostatic agent for compressible and non-compressible acute wounds |
| US9616088B2 (en) | 2013-03-13 | 2017-04-11 | Gel-E, Inc. | Advanced functional biocompatible polymer putty used as a hemostatic agent for treating damaged tissue and cells |
| EP3569262A1 (en) | 2013-03-14 | 2019-11-20 | Tricol Biomedical, Inc. | Biocompatible and bioabsorbable derivatized chitosan compositions |
| WO2017032897A1 (en) | 2015-08-27 | 2017-03-02 | Alimentary Health Limited | Use of bifidobacterium longum and an exopolysaccharide produced thereby |
| US10576099B2 (en) | 2016-10-21 | 2020-03-03 | Covidien Lp | Injectable scaffold for treatment of intracranial aneurysms and related technology |
| EP3532111B1 (en) * | 2016-10-26 | 2021-01-20 | Biointelligence Systems S.L. | Bone bioactive composition and uses thereof |
| GB2595144B (en) * | 2019-02-08 | 2023-07-26 | Chitogel Ltd | Surgical hydrogel |
| CN114630627A (zh) | 2019-11-04 | 2022-06-14 | 柯惠有限合伙公司 | 用于治疗颅内动脉瘤的装置、系统和方法 |
| US12364793B2 (en) | 2021-03-16 | 2025-07-22 | Covidien Lp | Injectable biopolymer compositions and associated systems and methods |
| EP4084580A1 (en) * | 2021-04-30 | 2022-11-02 | Koninklijke Philips N.V. | A light output system and design method |
| KR102852787B1 (ko) * | 2021-12-28 | 2025-08-28 | 단국대학교 천안캠퍼스 산학협력단 | 신규한 화합물을 포함하는 생리 식염수 |
| EP4572811A1 (en) * | 2022-11-10 | 2025-06-25 | Hemostasis LLC | Dressing formulations |
| CN116059430B (zh) * | 2022-12-16 | 2025-09-23 | 无锡学院 | 一种可降解伤口敷料及其制备方法 |
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