CA2927148A1 - Methods and compositions for treating cancer - Google Patents
Methods and compositions for treating cancer Download PDFInfo
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- CA2927148A1 CA2927148A1 CA2927148A CA2927148A CA2927148A1 CA 2927148 A1 CA2927148 A1 CA 2927148A1 CA 2927148 A CA2927148 A CA 2927148A CA 2927148 A CA2927148 A CA 2927148A CA 2927148 A1 CA2927148 A1 CA 2927148A1
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361895308P | 2013-10-24 | 2013-10-24 | |
| US61/895,308 | 2013-10-24 | ||
| PCT/US2014/061418 WO2015061229A1 (en) | 2013-10-24 | 2014-10-20 | Methods and compositions for treating cancer |
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| CA2927148A1 true CA2927148A1 (en) | 2015-04-30 |
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| CA2927148A Abandoned CA2927148A1 (en) | 2013-10-24 | 2014-10-20 | Methods and compositions for treating cancer |
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|---|---|
| US (2) | US9511050B2 (Direct) |
| EP (1) | EP3060207A4 (Direct) |
| JP (1) | JP6389884B2 (Direct) |
| KR (1) | KR20160065986A (Direct) |
| CN (1) | CN105848654B (Direct) |
| AU (1) | AU2014340398A1 (Direct) |
| CA (1) | CA2927148A1 (Direct) |
| IL (1) | IL245281A0 (Direct) |
| MX (1) | MX2016004678A (Direct) |
| RU (1) | RU2016114498A (Direct) |
| WO (1) | WO2015061229A1 (Direct) |
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| US8232310B2 (en) * | 2006-12-29 | 2012-07-31 | Georgetown University | Targeting of EWS-FLI1 as anti-tumor therapy |
| RS53350B (sr) | 2008-09-22 | 2014-10-31 | Array Biopharma, Inc. | Supstituisana jedinjenja imidazo[1,2-b]piridazina kao inhibitori trk kinaze |
| EP2350071B1 (en) | 2008-10-22 | 2014-01-08 | Array Biopharma, Inc. | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS |
| AR077468A1 (es) | 2009-07-09 | 2011-08-31 | Array Biopharma Inc | Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa |
| PL3205654T3 (pl) | 2010-05-20 | 2019-08-30 | Array Biopharma, Inc. | Związki makrocykliczne jako inhibitory kinazy TRK |
| EP2836481B1 (en) | 2012-04-12 | 2018-12-26 | Georgetown University | Compounds and compositions for treating ewings sarcoma family of tumors |
| JP6389884B2 (ja) * | 2013-10-24 | 2018-09-12 | ジョージタウン・ユニバーシティＧｅｏｒｇｅｔｏｗｎ Ｕｎｉｖｅｒｓｉｔｙ | 癌を治療するための方法及び組成物 |
| NZ730585A (en) | 2014-10-09 | 2018-08-31 | Oncternal Therapeutics Inc | Indolinone compounds and uses thereof |
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- 2014-10-20 CA CA2927148A patent/CA2927148A1/en not_active Abandoned
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- 2014-10-20 WO PCT/US2014/061418 patent/WO2015061229A1/en not_active Ceased
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| WO2015061229A1 (en) | 2015-04-30 |
| US20160263086A1 (en) | 2016-09-15 |
| KR20160065986A (ko) | 2016-06-09 |
| EP3060207A1 (en) | 2016-08-31 |
| US20170157089A1 (en) | 2017-06-08 |
| IL245281A0 (en) | 2016-06-30 |
| MX2016004678A (es) | 2017-03-10 |
| US9511050B2 (en) | 2016-12-06 |
| EP3060207A4 (en) | 2017-04-12 |
| JP2016534084A (ja) | 2016-11-04 |
| CN105848654A (zh) | 2016-08-10 |
| CN105848654B (zh) | 2018-10-02 |
| RU2016114498A3 (Direct) | 2018-08-13 |
| RU2016114498A (ru) | 2017-11-29 |
| AU2014340398A1 (en) | 2016-06-09 |
| JP6389884B2 (ja) | 2018-09-12 |
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