CA2926306C - A method for determining the total amount and/or concentration of an analyte in a sample - Google Patents

A method for determining the total amount and/or concentration of an analyte in a sample Download PDF

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Publication number
CA2926306C
CA2926306C CA2926306A CA2926306A CA2926306C CA 2926306 C CA2926306 C CA 2926306C CA 2926306 A CA2926306 A CA 2926306A CA 2926306 A CA2926306 A CA 2926306A CA 2926306 C CA2926306 C CA 2926306C
Authority
CA
Canada
Prior art keywords
molecule
analyte
binding
binding molecule
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2926306A
Other languages
English (en)
French (fr)
Other versions
CA2926306A1 (en
Inventor
Michael Schraeml
Markus Roessler
Michael Gerg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2926306A1 publication Critical patent/CA2926306A1/en
Application granted granted Critical
Publication of CA2926306C publication Critical patent/CA2926306C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2926306A 2013-11-05 2014-11-03 A method for determining the total amount and/or concentration of an analyte in a sample Active CA2926306C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP13005218 2013-11-05
EP13005218.6 2013-11-05
EP14002015.7 2014-06-11
EP14002015 2014-06-11
PCT/EP2014/073523 WO2015067547A1 (en) 2013-11-05 2014-11-03 A method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto

Publications (2)

Publication Number Publication Date
CA2926306A1 CA2926306A1 (en) 2015-05-14
CA2926306C true CA2926306C (en) 2022-12-06

Family

ID=51845410

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2926306A Active CA2926306C (en) 2013-11-05 2014-11-03 A method for determining the total amount and/or concentration of an analyte in a sample

Country Status (7)

Country Link
US (2) US10564151B2 (https=)
EP (1) EP3066469B1 (https=)
JP (1) JP6446044B2 (https=)
CN (1) CN105683755B (https=)
CA (1) CA2926306C (https=)
ES (1) ES2654906T3 (https=)
WO (1) WO2015067547A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180299436A1 (en) * 2017-01-20 2018-10-18 Shenzhen New Industries Biomedical Engineering Co., Ltd. A method, kit and system for preparing an antibody pair and the use of the kit
WO2024158727A2 (en) * 2023-01-24 2024-08-02 University Of Cincinnati Depletion-limited analyte sensing with non-equilibrium binding probes

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208479A (en) * 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
DE4214922C2 (de) 1992-05-06 1996-06-13 Brahms Diagnostica Gmbh Verfahren zur quantitativen Bestimmung des Anteils der freien Form eines Schilddrüsenhormon-Liganden in einer biologischen Flüssigkeit und Kit zur Durchführung eines solchen Verfahrens
US5312730A (en) 1992-05-27 1994-05-17 Ciba Corning Diagnostics Corp. Immune complex transfer with lypophilic bridge
JPH10513260A (ja) * 1995-01-31 1998-12-15 ノボ ノルディスク アクティーゼルスカブ 前臨床的に糖尿病を診断する方法
US6838250B2 (en) 2000-03-31 2005-01-04 Ortho-Clinical Diagnostics, Inc. Immunoassay for C-reactive protein
CA2535804A1 (en) * 2003-08-14 2005-03-03 Wyeth Anti-lewis y anti-idiotypic antibodies and uses thereof
MXPA06011824A (es) * 2004-04-16 2006-12-15 Genentech Inc Ensayo para anticuerpos.
EP1861708A2 (en) * 2005-03-08 2007-12-05 Tanox, Inc. Methods for determining the bivalency of protein and antibody therapeutics
US20090246795A1 (en) 2005-12-22 2009-10-01 Rohm Co., Ltd. Immunoassay device and method
EP1801594A1 (en) * 2005-12-23 2007-06-27 Koninklijke Philips Electronics N.V. Sensing device and method for determination of the amount of target molecule in an analyte
US20080127359A1 (en) * 2006-11-06 2008-05-29 Hermann Beck Method for producing anti-idiotypic antibodies
TWI434855B (zh) * 2006-11-21 2014-04-21 Hoffmann La Roche 結合物及其在免疫分析中作為參考標準之用途
MX2010002269A (es) 2007-08-28 2010-03-25 Abbott Biotech Ltd Composiciones y metodos que comprenden proteinas de union para adalimumab.
FR2980271B1 (fr) * 2011-09-16 2013-10-11 Cisbio Bioassays Procede de determination de la glycosylation d'un anticorps
CA2853917A1 (en) * 2011-12-19 2013-06-27 F. Hoffmann-La Roche Ag Method for the detection of free binding partner of a multispecific binder
JP2015507193A (ja) * 2012-02-01 2015-03-05 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 多重特異性結合物の結合パートナーを検出するための方法
MX346146B (es) * 2012-07-13 2017-03-09 Hoffmann La Roche Metodo para detectar un aglutinante multiespecifico.
PH12021552742A1 (en) * 2013-08-01 2022-05-23 Five Prime Therapeutics Inc Afucosylated anti-fgfr2iiib antibodies

Also Published As

Publication number Publication date
JP2016535266A (ja) 2016-11-10
HK1225799A1 (zh) 2017-09-15
EP3066469B1 (en) 2017-10-11
JP6446044B2 (ja) 2018-12-26
EP3066469A1 (en) 2016-09-14
CA2926306A1 (en) 2015-05-14
US20200141930A1 (en) 2020-05-07
US10564151B2 (en) 2020-02-18
ES2654906T8 (es) 2018-02-26
CN105683755A (zh) 2016-06-15
WO2015067547A1 (en) 2015-05-14
US12158466B2 (en) 2024-12-03
CN105683755B (zh) 2019-08-13
ES2654906T3 (es) 2018-02-15
US20160252500A1 (en) 2016-09-01

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