JP6446044B2 - 結合分子の存在下で被検体の総量および/または総濃度を決定するための方法、ならびにそれに関係するキット、組成物および使用 - Google Patents
結合分子の存在下で被検体の総量および/または総濃度を決定するための方法、ならびにそれに関係するキット、組成物および使用 Download PDFInfo
- Publication number
- JP6446044B2 JP6446044B2 JP2016527237A JP2016527237A JP6446044B2 JP 6446044 B2 JP6446044 B2 JP 6446044B2 JP 2016527237 A JP2016527237 A JP 2016527237A JP 2016527237 A JP2016527237 A JP 2016527237A JP 6446044 B2 JP6446044 B2 JP 6446044B2
- Authority
- JP
- Japan
- Prior art keywords
- molecule
- analyte
- binding
- antibody
- binding molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13005218 | 2013-11-05 | ||
| EP13005218.6 | 2013-11-05 | ||
| EP14002015.7 | 2014-06-11 | ||
| EP14002015 | 2014-06-11 | ||
| PCT/EP2014/073523 WO2015067547A1 (en) | 2013-11-05 | 2014-11-03 | A method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016535266A JP2016535266A (ja) | 2016-11-10 |
| JP2016535266A5 JP2016535266A5 (https=) | 2017-11-16 |
| JP6446044B2 true JP6446044B2 (ja) | 2018-12-26 |
Family
ID=51845410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016527237A Active JP6446044B2 (ja) | 2013-11-05 | 2014-11-03 | 結合分子の存在下で被検体の総量および/または総濃度を決定するための方法、ならびにそれに関係するキット、組成物および使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10564151B2 (https=) |
| EP (1) | EP3066469B1 (https=) |
| JP (1) | JP6446044B2 (https=) |
| CN (1) | CN105683755B (https=) |
| CA (1) | CA2926306C (https=) |
| ES (1) | ES2654906T3 (https=) |
| WO (1) | WO2015067547A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180299436A1 (en) * | 2017-01-20 | 2018-10-18 | Shenzhen New Industries Biomedical Engineering Co., Ltd. | A method, kit and system for preparing an antibody pair and the use of the kit |
| WO2024158727A2 (en) * | 2023-01-24 | 2024-08-02 | University Of Cincinnati | Depletion-limited analyte sensing with non-equilibrium binding probes |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4208479A (en) * | 1977-07-14 | 1980-06-17 | Syva Company | Label modified immunoassays |
| DE4214922C2 (de) | 1992-05-06 | 1996-06-13 | Brahms Diagnostica Gmbh | Verfahren zur quantitativen Bestimmung des Anteils der freien Form eines Schilddrüsenhormon-Liganden in einer biologischen Flüssigkeit und Kit zur Durchführung eines solchen Verfahrens |
| US5312730A (en) | 1992-05-27 | 1994-05-17 | Ciba Corning Diagnostics Corp. | Immune complex transfer with lypophilic bridge |
| JPH10513260A (ja) * | 1995-01-31 | 1998-12-15 | ノボ ノルディスク アクティーゼルスカブ | 前臨床的に糖尿病を診断する方法 |
| US6838250B2 (en) | 2000-03-31 | 2005-01-04 | Ortho-Clinical Diagnostics, Inc. | Immunoassay for C-reactive protein |
| CA2535804A1 (en) * | 2003-08-14 | 2005-03-03 | Wyeth | Anti-lewis y anti-idiotypic antibodies and uses thereof |
| MXPA06011824A (es) * | 2004-04-16 | 2006-12-15 | Genentech Inc | Ensayo para anticuerpos. |
| EP1861708A2 (en) * | 2005-03-08 | 2007-12-05 | Tanox, Inc. | Methods for determining the bivalency of protein and antibody therapeutics |
| US20090246795A1 (en) | 2005-12-22 | 2009-10-01 | Rohm Co., Ltd. | Immunoassay device and method |
| EP1801594A1 (en) * | 2005-12-23 | 2007-06-27 | Koninklijke Philips Electronics N.V. | Sensing device and method for determination of the amount of target molecule in an analyte |
| US20080127359A1 (en) * | 2006-11-06 | 2008-05-29 | Hermann Beck | Method for producing anti-idiotypic antibodies |
| TWI434855B (zh) * | 2006-11-21 | 2014-04-21 | Hoffmann La Roche | 結合物及其在免疫分析中作為參考標準之用途 |
| MX2010002269A (es) | 2007-08-28 | 2010-03-25 | Abbott Biotech Ltd | Composiciones y metodos que comprenden proteinas de union para adalimumab. |
| FR2980271B1 (fr) * | 2011-09-16 | 2013-10-11 | Cisbio Bioassays | Procede de determination de la glycosylation d'un anticorps |
| CA2853917A1 (en) * | 2011-12-19 | 2013-06-27 | F. Hoffmann-La Roche Ag | Method for the detection of free binding partner of a multispecific binder |
| JP2015507193A (ja) * | 2012-02-01 | 2015-03-05 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 多重特異性結合物の結合パートナーを検出するための方法 |
| MX346146B (es) * | 2012-07-13 | 2017-03-09 | Hoffmann La Roche | Metodo para detectar un aglutinante multiespecifico. |
| PH12021552742A1 (en) * | 2013-08-01 | 2022-05-23 | Five Prime Therapeutics Inc | Afucosylated anti-fgfr2iiib antibodies |
-
2014
- 2014-11-03 JP JP2016527237A patent/JP6446044B2/ja active Active
- 2014-11-03 ES ES14792817.0T patent/ES2654906T3/es active Active
- 2014-11-03 WO PCT/EP2014/073523 patent/WO2015067547A1/en not_active Ceased
- 2014-11-03 CA CA2926306A patent/CA2926306C/en active Active
- 2014-11-03 CN CN201480060361.3A patent/CN105683755B/zh active Active
- 2014-11-03 EP EP14792817.0A patent/EP3066469B1/en active Active
-
2016
- 2016-05-04 US US15/146,226 patent/US10564151B2/en active Active
-
2020
- 2020-01-06 US US16/734,884 patent/US12158466B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016535266A (ja) | 2016-11-10 |
| HK1225799A1 (zh) | 2017-09-15 |
| EP3066469B1 (en) | 2017-10-11 |
| EP3066469A1 (en) | 2016-09-14 |
| CA2926306A1 (en) | 2015-05-14 |
| US20200141930A1 (en) | 2020-05-07 |
| US10564151B2 (en) | 2020-02-18 |
| ES2654906T8 (es) | 2018-02-26 |
| CN105683755A (zh) | 2016-06-15 |
| WO2015067547A1 (en) | 2015-05-14 |
| US12158466B2 (en) | 2024-12-03 |
| CN105683755B (zh) | 2019-08-13 |
| ES2654906T3 (es) | 2018-02-15 |
| CA2926306C (en) | 2022-12-06 |
| US20160252500A1 (en) | 2016-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI796328B (zh) | B7-h3抗體、其抗原結合片段及其醫藥用途 | |
| JP6437913B2 (ja) | 複合体特異的抗体及び抗体断片並びにその使用 | |
| JP6602884B2 (ja) | ビタミンdの測定法 | |
| JP2022513694A (ja) | 抗pd-l1/抗4-1bb二重特異性抗体およびその使用 | |
| TW201323441A (zh) | 抗tnf之雙特異性免疫結合物 | |
| WO2014089209A2 (en) | Blood-brain barrier (bbb) penetrating dual specific binding proteins | |
| KR102661060B1 (ko) | 항인간 IgG4 모노클로날 항체, 및 그 항체를 이용한 인간 IgG4 측정 시약 | |
| TW202434888A (zh) | 用於偵測及測定包括生物流體在內之流體中之蛋白質結構及穩定性的方法 | |
| WO2026012501A1 (zh) | 一种抗ngf单克隆抗体及其应用 | |
| US12158466B2 (en) | Method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto | |
| CN109336973B (zh) | 抗转铁蛋白抗体及其用途 | |
| CN110343181B (zh) | 针对凝血因子ix(fix)的单域抗体 | |
| TW202204406A (zh) | 抗個體遺傳型抗體及使用其之方法 | |
| WO2024064600A2 (en) | B-cell maturation antigen (bcma) anti-idiotypic antibodies | |
| CA3232218A1 (en) | Assays to quantitate drug and target concentrations | |
| HK1225799B (zh) | 陷阱分子和检测分子的用途及其相关试剂盒和组合物 | |
| WO2022078490A1 (zh) | 抗erbb3抗体或其抗原结合片段及其医药用途 | |
| TWI869740B (zh) | 一種體外檢測sTNFR2蛋白濃度的方法及其檢測試劑和檢測試劑盒 | |
| US20250154242A1 (en) | Anti-tnf-alpha antibodies and compositions | |
| CN116744971A (zh) | 一种抗erbb3受体的抗体或其抗原结合片段及其医药用途 | |
| HK40096312A (zh) | 用於解析复杂、多步骤抗体相互作用的方法 | |
| IL300284A (en) | Compounds and methods directed against human and murine INSL5 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20171005 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20171005 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20180625 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20180705 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20181005 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20181102 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20181130 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6446044 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |