CA2913373C - Systeme d'elution de radioisotopes a auto-alignement - Google Patents
Systeme d'elution de radioisotopes a auto-alignement Download PDFInfo
- Publication number
- CA2913373C CA2913373C CA2913373A CA2913373A CA2913373C CA 2913373 C CA2913373 C CA 2913373C CA 2913373 A CA2913373 A CA 2913373A CA 2913373 A CA2913373 A CA 2913373A CA 2913373 C CA2913373 C CA 2913373C
- Authority
- CA
- Canada
- Prior art keywords
- shield
- radioisotope
- cap
- eluant
- elution system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000010828 elution Methods 0.000 title claims abstract description 137
- 230000005855 radiation Effects 0.000 claims abstract description 34
- 239000000463 material Substances 0.000 claims description 13
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 claims description 8
- 229910052721 tungsten Inorganic materials 0.000 claims description 8
- 239000010937 tungsten Substances 0.000 claims description 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- 239000011780 sodium chloride Substances 0.000 claims description 5
- 239000004033 plastic Substances 0.000 claims description 4
- JFALSRSLKYAFGM-UHFFFAOYSA-N uranium(0) Chemical compound [U] JFALSRSLKYAFGM-UHFFFAOYSA-N 0.000 claims description 4
- 230000013011 mating Effects 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- 230000000295 complement effect Effects 0.000 abstract description 18
- 229940121896 radiopharmaceutical Drugs 0.000 description 20
- 239000012217 radiopharmaceutical Substances 0.000 description 20
- 230000002799 radiopharmaceutical effect Effects 0.000 description 20
- 238000000034 method Methods 0.000 description 17
- 238000009206 nuclear medicine Methods 0.000 description 13
- 230000008569 process Effects 0.000 description 13
- 210000000056 organ Anatomy 0.000 description 10
- 239000003795 chemical substances by application Substances 0.000 description 9
- 238000003384 imaging method Methods 0.000 description 9
- 238000013519 translation Methods 0.000 description 9
- 239000012530 fluid Substances 0.000 description 8
- 239000012857 radioactive material Substances 0.000 description 8
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 description 7
- 229940056501 technetium 99m Drugs 0.000 description 7
- 230000002285 radioactive effect Effects 0.000 description 6
- ZOKXTWBITQBERF-AKLPVKDBSA-N Molybdenum Mo-99 Chemical compound [99Mo] ZOKXTWBITQBERF-AKLPVKDBSA-N 0.000 description 5
- 206010028980 Neoplasm Diseases 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 239000012141 concentrate Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 229950009740 molybdenum mo-99 Drugs 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 238000011161 development Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- SIJNDWFHVBDXDY-IEOVAKBOSA-N [hydroxy(phosphono)methyl]phosphonic acid;technetium-99 Chemical compound [99Tc].OP(=O)(O)C(O)P(O)(O)=O SIJNDWFHVBDXDY-IEOVAKBOSA-N 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 229940127043 diagnostic radiopharmaceutical Drugs 0.000 description 1
- 230000005489 elastic deformation Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229940055742 indium-111 Drugs 0.000 description 1
- APFVFJFRJDLVQX-AHCXROLUSA-N indium-111 Chemical compound [111In] APFVFJFRJDLVQX-AHCXROLUSA-N 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000012633 nuclear imaging Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 229920005668 polycarbonate resin Polymers 0.000 description 1
- 239000004431 polycarbonate resin Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 230000006335 response to radiation Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- BKVIYDNLLOSFOA-OIOBTWANSA-N thallium-201 Chemical compound [201Tl] BKVIYDNLLOSFOA-OIOBTWANSA-N 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
- G21F5/00—Transportable or portable shielded containers
- G21F5/06—Details of, or accessories to, the containers
- G21F5/12—Closures for containers; Sealing arrangements
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
- G21F3/00—Shielding characterised by its physical form, e.g. granules, or shape of the material
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
- G21F5/00—Transportable or portable shielded containers
- G21F5/015—Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation units; Radioisotope containers
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
- G21F5/00—Transportable or portable shielded containers
- G21F5/015—Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation units; Radioisotope containers
- G21F5/018—Syringe shields or holders
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/0005—Isotope delivery systems
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
- G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21H—OBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
- G21H5/00—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for
- G21H5/02—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for as tracers
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
- G21F5/00—Transportable or portable shielded containers
- G21F5/06—Details of, or accessories to, the containers
Landscapes
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Un système délution de radioisotopes comprend un générateur de radioisotopes présentant une structure dalignement. La structure dalignement peut être configurée pour faire interface avec une structure dalignement complémentaire dun dispositif protecteur de rayonnement auxiliaire.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84986906P | 2006-10-06 | 2006-10-06 | |
| US60/849,869 | 2006-10-06 | ||
| CA2665193A CA2665193C (fr) | 2006-10-06 | 2007-10-03 | Systeme d'elution de radioisotopes a auto-alignement |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2665193A Division CA2665193C (fr) | 2006-10-06 | 2007-10-03 | Systeme d'elution de radioisotopes a auto-alignement |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2913373A1 CA2913373A1 (fr) | 2008-04-17 |
| CA2913373C true CA2913373C (fr) | 2017-11-07 |
Family
ID=39156642
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2913373A Active CA2913373C (fr) | 2006-10-06 | 2007-10-03 | Systeme d'elution de radioisotopes a auto-alignement |
| CA2665193A Active CA2665193C (fr) | 2006-10-06 | 2007-10-03 | Systeme d'elution de radioisotopes a auto-alignement |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2665193A Active CA2665193C (fr) | 2006-10-06 | 2007-10-03 | Systeme d'elution de radioisotopes a auto-alignement |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US8431909B2 (fr) |
| EP (3) | EP3101659B1 (fr) |
| CA (2) | CA2913373C (fr) |
| ES (3) | ES2751731T3 (fr) |
| PL (1) | PL3270383T3 (fr) |
| WO (1) | WO2008045298A2 (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2512930C2 (ru) | 2008-06-11 | 2014-04-10 | Бракко Дайэгностикс Инк. | Конфигурации инфузионной системы |
| US9597053B2 (en) | 2008-06-11 | 2017-03-21 | Bracco Diagnostics Inc. | Infusion systems including computer-facilitated maintenance and/or operation and methods of use |
| US8317674B2 (en) | 2008-06-11 | 2012-11-27 | Bracco Diagnostics Inc. | Shielding assemblies for infusion systems |
| US8708352B2 (en) | 2008-06-11 | 2014-04-29 | Bracco Diagnostics Inc. | Cabinet structure configurations for infusion systems |
| US7862534B2 (en) | 2008-06-11 | 2011-01-04 | Bracco Diagnostics Inc. | Infusion circuit subassemblies |
| ITPD20100186A1 (it) * | 2010-06-11 | 2011-12-12 | Attilio Cecchin | Apparecchio per eluizione e procedimento di eluizione |
| US8866104B2 (en) | 2011-01-19 | 2014-10-21 | Mallinckrodt Llc | Radioisotope elution system |
| US9153350B2 (en) * | 2011-01-19 | 2015-10-06 | Mallinckrodt Llc | Protective shroud for nuclear pharmacy generators |
| US8809804B2 (en) * | 2011-01-19 | 2014-08-19 | Mallinckrodt Llc | Holder and tool for radioisotope elution system |
| US9161727B2 (en) | 2011-09-01 | 2015-10-20 | Hologic Inc | Independently rotatable detector plate for medical imaging device |
| US8872124B2 (en) | 2013-03-13 | 2014-10-28 | Mallinckrodt Llc | Systems and methods for assaying an eluate for technetium and molybdenum content |
| US9766351B2 (en) | 2014-03-13 | 2017-09-19 | Bracco Diagnostics Inc. | Real time nuclear isotope detection |
| AU2017332261A1 (en) | 2016-09-20 | 2019-04-11 | Bracco Diagnostics Inc. | Systems and techniques for generating, infusing, and controlling radioisotope delivery |
| US11810685B2 (en) | 2018-03-28 | 2023-11-07 | Bracco Diagnostics Inc. | Early detection of radioisotope generator end life |
| WO2019191384A1 (fr) | 2018-03-28 | 2019-10-03 | Bracco Diagnostics Inc. | Systèmes et techniques d'étalonnage des systèmes de distribution de radio-isotopes à l'aide d'un détecteur gamma |
| TR2023011175A1 (tr) * | 2023-09-08 | 2025-01-21 | Eczacibasi Monrol Nuekleer Ueruenler Sanayi Ve Ticaret Anonim Sirketi | Radyoi̇zotop elüzyon si̇stemi̇ i̇çi̇n taşima konteyniri |
| TR2023011183A1 (tr) * | 2023-09-08 | 2025-01-21 | Eczacibasi Monrol Nuekleer Ueruenler Sanayi Ve Ticaret Anonim Sirketi | Radyoi̇zotop elüzyon si̇stemi̇ i̇çi̇n taşima konteyniri |
| TR2023011170A1 (tr) * | 2023-09-08 | 2025-01-21 | Eczacibasi Monrol Nuekleer Ueruenler Sanayi Ve Ticaret Anonim Sirketi | Radyoi̇zotop elüzyon si̇stemi̇ i̇çi̇n taşima konteyniri |
| TR2023019212A1 (tr) * | 2023-12-28 | 2025-01-21 | Eczacibasi Monrol Nuekleer Ueruenler Sanayi Ve Ticaret Anonim Sirketi | Modüler hücrelere sahi̇p bi̇r radyoi̇zotop elüzyon si̇stemi̇ |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3615869A (en) * | 1965-07-26 | 1971-10-26 | Teledyne Inc | Radioisotope thermoelectric generator |
| US3369121A (en) * | 1966-04-06 | 1968-02-13 | Squibb & Sons Inc | Radioactive package and container therefor |
| US3663306A (en) * | 1968-11-06 | 1972-05-16 | Sanders Nuclear Corp | High pressure resistant compact housing structure |
| US3655981A (en) * | 1968-11-29 | 1972-04-11 | Mallinckrodt Chemical Works | Closed system generation and containerization of radioisotopes for eluting a daughter radioisotope from a parent radioisotope |
| US3710118A (en) * | 1970-05-25 | 1973-01-09 | Mallinckrodt Chemical Works | Radioisotope generator |
| DE2236565C3 (de) * | 1972-07-26 | 1979-05-03 | Hoechst Ag, 6000 Frankfurt | Vorrichtung zum Herstellen von sterilen, injizierbaren Eluaten durch Eluieren von Nuklidgeneratoren |
| NO141829C (no) * | 1973-05-04 | 1980-05-21 | Squibb & Sons Inc | Generator for sterilt, utvaskbart radioaktivt materiale |
| US3920995A (en) * | 1973-05-04 | 1975-11-18 | Squibb & Sons Inc | Radioactive material generator |
| US3946238A (en) * | 1974-08-05 | 1976-03-23 | Chevron Research Company | Shielded radioisotope generator and method for using same |
| US4020351A (en) * | 1975-06-16 | 1977-04-26 | Union Carbide Corporation | Generator system |
| US4084097A (en) * | 1976-12-15 | 1978-04-11 | E. R. Squibb & Sons, Inc. | Shielded container |
| DE2712635C2 (de) * | 1977-03-23 | 1982-04-29 | Hoechst Ag, 6000 Frankfurt | Nuklidgenerator zur Herstellung von Radionukliden |
| US4663115A (en) * | 1978-08-14 | 1987-05-05 | Virginia Russell | Protecting personnel and the environment from radioactive emissions by controlling such emissions and safely disposing of their energy |
| US4160910A (en) * | 1977-06-20 | 1979-07-10 | Union Carbide Corporation | Rechargeable 99MO/99MTC generator system |
| US4245685A (en) * | 1978-08-15 | 1981-01-20 | Mallinckrodt, Inc. | Protective carrier |
| NL7902342A (nl) * | 1979-03-26 | 1980-09-30 | Byk Mallinckrodt Cil Bv | Isotopengenerator. |
| US4308460A (en) * | 1980-07-31 | 1981-12-29 | The United States Of America As Represented By The United States Department Of Energy | Storage containers for radioactive material |
| CS255601B1 (en) * | 1984-05-18 | 1988-03-15 | Kristian Svoboda | 99 mtc elution unit-built generator and method of its production |
| US4846235A (en) * | 1986-01-29 | 1989-07-11 | Halliburton Company | Radioactivity shielding transportation assembly |
| US5111099A (en) * | 1990-03-02 | 1992-05-05 | Genesis Energy Systems, Inc. | Apparatus and method for converting radioactive energy into electrical energy |
| US5109160A (en) | 1990-10-12 | 1992-04-28 | E. I. Du Pont De Nemours And Company | Sterilizable radionuclide generator and method for sterilizing the same |
| US5109196A (en) * | 1991-03-05 | 1992-04-28 | Vanderbilt University | Method and apparatus for magnetic identification and localization of flaws in conductors by canceling the field about the conductor with the field about a flawless conductor |
| US5274239A (en) * | 1992-07-23 | 1993-12-28 | Sunol Technologies, Inc. | Shielded dose calibration apparatus |
| US5479969A (en) * | 1992-08-19 | 1996-01-02 | British Nuclear Fuels Plc | Apparatus for dispensing substances which are biologically hazardous |
| GB9217616D0 (en) * | 1992-08-19 | 1992-09-30 | British Nuclear Fuels Plc | Dispensing apparatus |
| JP3540497B2 (ja) * | 1995-04-20 | 2004-07-07 | 日本メジフィジックス株式会社 | 放射性物質用遮蔽部材の製造方法 |
| US5734169A (en) * | 1996-04-04 | 1998-03-31 | Saidian; David | Radioactive waste storage and disposal receptacle |
| USD389761S (en) * | 1996-11-12 | 1998-01-27 | Chromatography Research Supplies, Inc. | Cartridge cap |
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| GB2382453B (en) | 2002-04-11 | 2004-05-19 | Amersham Plc | Radioisotope generator and method of construction thereof |
| US8231858B2 (en) * | 2003-02-10 | 2012-07-31 | Ge Healthcare Limited | Diagnostic imaging agents with MMP inhibitory activity |
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| JP2008540038A (ja) * | 2005-05-16 | 2008-11-20 | マリンクロッド・インコーポレイテッド | 放射性薬剤ピッグ及び携帯自動注入器 |
| US20080167621A1 (en) * | 2005-05-16 | 2008-07-10 | Wagner Gary S | Multi-Barrel Syringe Having Integral Manifold |
| US8003967B2 (en) * | 2005-07-27 | 2011-08-23 | Mallinckrodt Llc | Radiation-shielding assemblies and methods of using the same |
| CA2616834A1 (fr) * | 2005-07-27 | 2007-02-08 | Mallinckrodt Inc. | Distributeur de produits pharmaco-radioactifs ayant un mecanisme d'acces a contre-force et systeme et procede concernant celui-ci |
| EP1942505A2 (fr) * | 2005-07-27 | 2008-07-09 | Mallinckrodt, Inc. | Ensembles et procédés de protection contre les radiations |
| CN101233582A (zh) * | 2005-07-27 | 2008-07-30 | 马林克罗特公司 | 与放射性同位素发生器一起使用的对准适配器及使用方法 |
| CA2618604A1 (fr) * | 2005-08-09 | 2007-03-05 | Mallinckrodt Inc. | Systeme de generation de radio-isotopes partiellement aptes a l'elution |
| ES2325840T3 (es) * | 2005-08-12 | 2009-09-21 | Mallinckrodt, Inc. | Conjunto de blindaje contra radiacion con un elemento de localizacion del recipiente. |
| EP1938339A2 (fr) * | 2005-08-29 | 2008-07-02 | Mallinckrodt, Inc. | Système et procédé d'élution d'un radioisotope introduit dans un contenant disposé à l'extérieur d'un générateur de radioisotopes |
| US7838844B2 (en) * | 2005-10-03 | 2010-11-23 | Mallinckrodt Inc. | Radiopharmaceutical system and method utilizing radio-frequency identification tags |
| US7700926B2 (en) * | 2006-01-12 | 2010-04-20 | Draximage General Partnership | Systems and methods for radioisotope generation |
-
2007
- 2007-10-03 EP EP16180032.1A patent/EP3101659B1/fr active Active
- 2007-10-03 EP EP07852540.9A patent/EP2074633B8/fr active Active
- 2007-10-03 EP EP17183074.8A patent/EP3270383B1/fr active Active
- 2007-10-03 WO PCT/US2007/021344 patent/WO2008045298A2/fr not_active Ceased
- 2007-10-03 CA CA2913373A patent/CA2913373C/fr active Active
- 2007-10-03 CA CA2665193A patent/CA2665193C/fr active Active
- 2007-10-03 ES ES17183074T patent/ES2751731T3/es active Active
- 2007-10-03 PL PL17183074T patent/PL3270383T3/pl unknown
- 2007-10-03 US US12/441,919 patent/US8431909B2/en active Active
- 2007-10-03 ES ES07852540.9T patent/ES2593910T3/es active Active
- 2007-10-03 ES ES16180032.1T patent/ES2641727T3/es active Active
-
2011
- 2011-11-23 US US13/303,723 patent/US8785882B2/en active Active
-
2013
- 2013-04-03 US US13/855,971 patent/US8809805B2/en active Active
-
2014
- 2014-06-27 US US14/317,522 patent/US9029799B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008045298A3 (fr) | 2008-08-07 |
| CA2665193A1 (fr) | 2008-04-17 |
| US8785882B2 (en) | 2014-07-22 |
| US8809805B2 (en) | 2014-08-19 |
| EP3101659B1 (fr) | 2017-07-26 |
| US20140306130A1 (en) | 2014-10-16 |
| US8431909B2 (en) | 2013-04-30 |
| EP3270383B1 (fr) | 2019-08-28 |
| WO2008045298A2 (fr) | 2008-04-17 |
| US20120298880A1 (en) | 2012-11-29 |
| US20090266998A1 (en) | 2009-10-29 |
| EP2074633A2 (fr) | 2009-07-01 |
| ES2593910T3 (es) | 2016-12-14 |
| EP2074633B1 (fr) | 2016-07-20 |
| CA2665193C (fr) | 2016-02-09 |
| US9029799B2 (en) | 2015-05-12 |
| ES2751731T3 (es) | 2020-04-01 |
| US20130234052A1 (en) | 2013-09-12 |
| EP3101659A1 (fr) | 2016-12-07 |
| EP2074633B8 (fr) | 2016-09-21 |
| EP3270383A1 (fr) | 2018-01-17 |
| PL3270383T3 (pl) | 2020-04-30 |
| ES2641727T3 (es) | 2017-11-13 |
| CA2913373A1 (fr) | 2008-04-17 |
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