CA2908832C - Inhibitors of metastasis - Google Patents
Inhibitors of metastasis Download PDFInfo
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- CA2908832C CA2908832C CA2908832A CA2908832A CA2908832C CA 2908832 C CA2908832 C CA 2908832C CA 2908832 A CA2908832 A CA 2908832A CA 2908832 A CA2908832 A CA 2908832A CA 2908832 C CA2908832 C CA 2908832C
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
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- Biophysics (AREA)
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- Peptides Or Proteins (AREA)
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| US201361808966P | 2013-04-05 | 2013-04-05 | |
| US61/808,966 | 2013-04-05 | ||
| PCT/US2014/033206 WO2014165853A1 (en) | 2013-04-05 | 2014-04-07 | Inhibitors of metastasis |
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| CA2908832A1 CA2908832A1 (en) | 2014-10-09 |
| CA2908832C true CA2908832C (en) | 2023-01-24 |
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| CA2908832A Active CA2908832C (en) | 2013-04-05 | 2014-04-07 | Inhibitors of metastasis |
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| RU2681213C2 (ru) | 2013-04-05 | 2019-03-05 | Байомарк Фармасьютикалз, Лтд. | Ингибиторы метастазирования |
| CN108686220A (zh) * | 2018-07-13 | 2018-10-23 | 刘慧荣 | 一种针对甲状腺癌的抗肿瘤剂 |
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| US8501911B2 (en) | 1999-02-24 | 2013-08-06 | Biomarck Pharmaceuticals, Ltd | Methods of reducing inflammation and mucus hypersecretion |
| US7544772B2 (en) * | 2001-06-26 | 2009-06-09 | Biomarck Pharmaceuticals, Ltd. | Methods for regulating inflammatory mediators and peptides useful therein |
| US7265088B1 (en) | 2000-02-24 | 2007-09-04 | North Carolina State University | Method and compositions for altering mucus secretion |
| AU2002322475B2 (en) | 2001-06-26 | 2008-02-21 | North Carolina State University | Blocking peptide for inflammatory cell secretion |
| AU2002362753B9 (en) * | 2001-10-05 | 2008-05-15 | The Trustees Of The University Of Pennsylvania | Compositions for and methods of treating and preventing sirs/sepsis |
| DE60308251T2 (de) | 2002-04-17 | 2007-08-30 | Canon K.K. | Vorrichtung zur Bereitstellung von öffentlichen Schlüsselzertifikaten |
| US7524926B2 (en) | 2005-01-20 | 2009-04-28 | Biomarck Pharmaceuticals, Ltd. | Mucin hypersecretion inhibitors and methods of use |
| WO2006086681A2 (en) * | 2005-02-09 | 2006-08-17 | Beth Israel Deaconess Medical Center, Inc. | Methods of inhibiting smooth muscle cell migration and proliferation |
| PT2053915E (pt) * | 2006-07-26 | 2014-08-25 | Biomarck Pharmaceuticals Ltd | Peptídeos para atenuar a libertação de mediadores inflamatórios |
| EP2069477A4 (en) | 2006-10-06 | 2010-12-08 | Celtaxsys Inc | CHEMICAL REPULSION OF CELLS |
| EP2078204A2 (en) * | 2006-10-27 | 2009-07-15 | George Mason Intellectual Properties, Inc. | Assay for metastatic colorectal cancer |
| WO2009062128A2 (en) * | 2007-11-08 | 2009-05-14 | Indiana University Research And Technology Corporation | Combination drug therapy for the treatment of cancer |
| EP2105511A1 (en) * | 2008-03-28 | 2009-09-30 | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. | Medicament compositions and substances for treatment and identifying adenocarcinoma of the lung |
| US9073974B2 (en) * | 2009-12-21 | 2015-07-07 | The Regents Of The University Of California | RGD-containing cyclic peptides |
| JP6225104B2 (ja) * | 2011-04-08 | 2017-11-01 | タフツ メディカル センター インコーポレイテッドＴｕｆｔｓ Ｍｅｄｉｃａｌ Ｃｅｎｔｅｒ，Ｉｎｃ． | ペプデューシンの設計および使用 |
| RU2681213C2 (ru) | 2013-04-05 | 2019-03-05 | Байомарк Фармасьютикалз, Лтд. | Ингибиторы метастазирования |
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2014
- 2014-04-07 RU RU2015146997A patent/RU2681213C2/ru active
- 2014-04-07 BR BR112015025398A patent/BR112015025398A2/pt not_active Application Discontinuation
- 2014-04-07 SG SG10201708125PA patent/SG10201708125PA/en unknown
- 2014-04-07 CN CN201480031461.3A patent/CN105517562B/zh not_active Expired - Fee Related
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- 2014-04-07 AU AU2014247979A patent/AU2014247979B2/en not_active Ceased
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- 2014-04-07 MX MX2015014036A patent/MX363077B/es unknown
- 2014-04-07 JP JP2016506681A patent/JP6449849B2/ja not_active Expired - Fee Related
- 2014-04-07 KR KR1020157031658A patent/KR102191695B1/ko not_active Expired - Fee Related
- 2014-04-07 US US14/246,864 patent/US9408886B2/en active Active - Reinstated
- 2014-04-07 DK DK14779844.1T patent/DK2981279T3/en active
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- 2014-04-07 SG SG11201508249WA patent/SG11201508249WA/en unknown
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2015
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- 2015-10-28 ZA ZA2015/08010A patent/ZA201508010B/en unknown
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2016
- 2016-07-06 US US15/203,376 patent/US10011636B2/en active Active
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2018
- 2018-06-04 US US15/996,797 patent/US10683328B2/en active Active - Reinstated
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2020
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