MX2015014036A - Inhibidores de metastasis. - Google Patents

Inhibidores de metastasis.

Info

Publication number
MX2015014036A
MX2015014036A MX2015014036A MX2015014036A MX2015014036A MX 2015014036 A MX2015014036 A MX 2015014036A MX 2015014036 A MX2015014036 A MX 2015014036A MX 2015014036 A MX2015014036 A MX 2015014036A MX 2015014036 A MX2015014036 A MX 2015014036A
Authority
MX
Mexico
Prior art keywords
metastasis
inhibitors
methods
inhibiting
cancers
Prior art date
Application number
MX2015014036A
Other languages
English (en)
Other versions
MX363077B (es
Inventor
Indu Parikh
Kenneth B Adler
Original Assignee
Biomarck Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomarck Pharmaceuticals Ltd filed Critical Biomarck Pharmaceuticals Ltd
Publication of MX2015014036A publication Critical patent/MX2015014036A/es
Publication of MX363077B publication Critical patent/MX363077B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C12N2310/141—MicroRNAs, miRNAs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Virology (AREA)

Abstract

La presente invención se refiere a métodos y compuestos para tratar o prevenir el cáncer. Los métodos y composiciones que se proporcionan incluyen inhibición o supresión del desarrollo, mantenimiento y proliferación de cánceres, incluido el bloqueo o inhibición de la metástasis de células cancerosas.
MX2015014036A 2013-04-05 2014-04-07 Inhibidores de metastasis. MX363077B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361808966P 2013-04-05 2013-04-05
PCT/US2014/033206 WO2014165853A1 (en) 2013-04-05 2014-04-07 Inhibitors of metastasis

Publications (2)

Publication Number Publication Date
MX2015014036A true MX2015014036A (es) 2016-02-25
MX363077B MX363077B (es) 2019-03-07

Family

ID=51654619

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015014036A MX363077B (es) 2013-04-05 2014-04-07 Inhibidores de metastasis.

Country Status (20)

Country Link
US (4) US9408886B2 (es)
EP (1) EP2981279B1 (es)
JP (1) JP6449849B2 (es)
KR (1) KR102191695B1 (es)
CN (1) CN105517562B (es)
AU (1) AU2014247979B2 (es)
BR (1) BR112015025398A2 (es)
CA (1) CA2908832C (es)
DK (1) DK2981279T3 (es)
ES (1) ES2714863T3 (es)
HK (1) HK1221159A1 (es)
HU (1) HUE043971T2 (es)
IL (1) IL241937B (es)
MX (1) MX363077B (es)
PL (1) PL2981279T3 (es)
PT (1) PT2981279T (es)
RU (1) RU2681213C2 (es)
SG (2) SG11201508249WA (es)
WO (1) WO2014165853A1 (es)
ZA (1) ZA201508010B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2981279T3 (pl) 2013-04-05 2019-09-30 Biomarck Pharmaceuticals Ltd. Inhibitory peptydowe marcks do hamowania przerzutów
CN108686220A (zh) * 2018-07-13 2018-10-23 刘慧荣 一种针对甲状腺癌的抗肿瘤剂

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8501911B2 (en) 1999-02-24 2013-08-06 Biomarck Pharmaceuticals, Ltd Methods of reducing inflammation and mucus hypersecretion
US7544772B2 (en) 2001-06-26 2009-06-09 Biomarck Pharmaceuticals, Ltd. Methods for regulating inflammatory mediators and peptides useful therein
US7265088B1 (en) 2000-02-24 2007-09-04 North Carolina State University Method and compositions for altering mucus secretion
ATE519493T1 (de) 2001-06-26 2011-08-15 Univ North Carolina State Blockierendes peptid für die sekretion von entzündungszellen
EP1453548A4 (en) * 2001-10-05 2005-10-26 Univ Pennsylvania COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF SIRS (SUPPRESSOR OF IMMUNE RESPONSES FACTOR) / SEPSIS
EP1355447B1 (en) 2002-04-17 2006-09-13 Canon Kabushiki Kaisha Public key certification providing apparatus
RU2423379C2 (ru) 2005-01-20 2011-07-10 Байомарк Фармасьютикалз, Лтд. Ингибиторы гиперсекреции муцина и способы их применения
WO2006086681A2 (en) 2005-02-09 2006-08-17 Beth Israel Deaconess Medical Center, Inc. Methods of inhibiting smooth muscle cell migration and proliferation
DK2053915T3 (da) * 2006-07-26 2014-06-30 Biomarck Pharmaceuticals Ltd Peptider til reducering af frigørelse af inflammatoriske mediatorer
US20080213319A1 (en) 2006-10-06 2008-09-04 Hyun Kang Chemorepulsion of cells
WO2008057305A2 (en) * 2006-10-27 2008-05-15 George Mason Intellectual Properties, Inc. Assay for metastatic colorectal cancer
WO2009062128A2 (en) 2007-11-08 2009-05-14 Indiana University Research And Technology Corporation Combination drug therapy for the treatment of cancer
EP2105511A1 (en) * 2008-03-28 2009-09-30 Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. Medicament compositions and substances for treatment and identifying adenocarcinoma of the lung
WO2011079015A1 (en) 2009-12-21 2011-06-30 The Regents Of The University Of California Rgd-containing cyclic peptides
WO2012139137A2 (en) * 2011-04-08 2012-10-11 Tufts Medical Center, Inc. Pepducin design and use
PL2981279T3 (pl) * 2013-04-05 2019-09-30 Biomarck Pharmaceuticals Ltd. Inhibitory peptydowe marcks do hamowania przerzutów

Also Published As

Publication number Publication date
EP2981279A4 (en) 2016-11-09
BR112015025398A2 (pt) 2017-10-10
CA2908832A1 (en) 2014-10-09
JP6449849B2 (ja) 2019-01-09
HUE043971T2 (hu) 2019-09-30
US10683328B2 (en) 2020-06-16
KR102191695B1 (ko) 2020-12-16
US10011636B2 (en) 2018-07-03
CN105517562A (zh) 2016-04-20
US20210130403A1 (en) 2021-05-06
HK1221159A1 (zh) 2017-05-26
PT2981279T (pt) 2019-03-14
DK2981279T3 (en) 2019-03-25
SG10201708125PA (en) 2017-11-29
JP2016516756A (ja) 2016-06-09
CA2908832C (en) 2023-01-24
IL241937B (en) 2019-03-31
US11466054B2 (en) 2022-10-11
US20140302057A1 (en) 2014-10-09
AU2014247979A1 (en) 2015-10-29
EP2981279A1 (en) 2016-02-10
RU2015146997A3 (es) 2018-03-13
AU2014247979B2 (en) 2018-06-28
RU2681213C2 (ru) 2019-03-05
KR20150140736A (ko) 2015-12-16
RU2015146997A (ru) 2017-05-15
US9408886B2 (en) 2016-08-09
NZ712955A (en) 2021-03-26
ZA201508010B (en) 2017-01-25
PL2981279T3 (pl) 2019-09-30
CN105517562B (zh) 2018-12-28
ES2714863T3 (es) 2019-05-30
US20190119320A1 (en) 2019-04-25
SG11201508249WA (en) 2015-11-27
US20170121369A1 (en) 2017-05-04
EP2981279B1 (en) 2018-12-19
MX363077B (es) 2019-03-07
WO2014165853A1 (en) 2014-10-09

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