CA2888379A1 - Composes 3,4-bis(catechol)pyrrole-n-substitues, leur preparation et utilisation dans le traitement du cancer - Google Patents

Composes 3,4-bis(catechol)pyrrole-n-substitues, leur preparation et utilisation dans le traitement du cancer Download PDF

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Publication number
CA2888379A1
CA2888379A1 CA2888379A CA2888379A CA2888379A1 CA 2888379 A1 CA2888379 A1 CA 2888379A1 CA 2888379 A CA2888379 A CA 2888379A CA 2888379 A CA2888379 A CA 2888379A CA 2888379 A1 CA2888379 A1 CA 2888379A1
Authority
CA
Canada
Prior art keywords
compound
cancer
formula
alkyl
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2888379A
Other languages
English (en)
French (fr)
Inventor
Pascal Collin
Maxim Egorov
Bernard Delpech
Joanna Bakala
Maria Achab
Jerome Bignon
Odile Thoison
Michel BENECHIE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Publication of CA2888379A1 publication Critical patent/CA2888379A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA2888379A 2012-10-16 2013-10-14 Composes 3,4-bis(catechol)pyrrole-n-substitues, leur preparation et utilisation dans le traitement du cancer Abandoned CA2888379A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1259868 2012-10-16
FR1259868A FR2996847B1 (fr) 2012-10-16 2012-10-16 Composes 3,4-bis(catechol)pyrrole-n-substitues, leur preparation et utilisation dans le traitement du cancer
PCT/EP2013/071445 WO2014060366A1 (fr) 2012-10-16 2013-10-14 Composes 3,4-bis(catechol)pyrrole-n-substitues, leur preparation et utilisation dans le traitement du cancer

Publications (1)

Publication Number Publication Date
CA2888379A1 true CA2888379A1 (fr) 2014-04-24

Family

ID=47425104

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2888379A Abandoned CA2888379A1 (fr) 2012-10-16 2013-10-14 Composes 3,4-bis(catechol)pyrrole-n-substitues, leur preparation et utilisation dans le traitement du cancer

Country Status (8)

Country Link
US (1) US9546159B2 (https=)
EP (1) EP2909171B1 (https=)
JP (1) JP6423349B2 (https=)
AU (1) AU2013331764B2 (https=)
CA (1) CA2888379A1 (https=)
ES (1) ES2608781T3 (https=)
FR (1) FR2996847B1 (https=)
WO (1) WO2014060366A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3022244B1 (fr) * 2014-06-17 2016-07-01 Centre Nat De La Rech Scient (Cnrs) Utilisation d'un nouveau compose 3-aryl-4-catechol-pyrrole-n-propanol et ses derives pour le traitement du cancer et des pathologies associees a une angiogenese excessive
CN121154883A (zh) * 2020-05-25 2025-12-19 医工瑞思(福建)工程研究中心有限公司 一种大面积创伤急救敷料套件及其使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019045A1 (en) * 1992-03-26 1993-09-30 E.I. Du Pont De Nemours And Company Arthropodicidal amides
DE19756261A1 (de) * 1997-12-17 1999-07-01 Klinge Co Chem Pharm Fab Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide
GB9821975D0 (en) * 1998-10-08 1998-12-02 Pharma Mar Sa New cytotoxic alkaloids
WO2008064317A1 (en) * 2006-11-22 2008-05-29 University Of Medicine And Dentistry Of New Jersey Lipophilic opioid receptor active compounds
WO2008064318A2 (en) * 2006-11-22 2008-05-29 University Of Medicine And Dentistry Of New Jersey Peripheral opioid receptor active compounds

Also Published As

Publication number Publication date
JP2015534958A (ja) 2015-12-07
ES2608781T3 (es) 2017-04-17
FR2996847B1 (fr) 2014-12-05
JP6423349B2 (ja) 2018-11-14
AU2013331764B2 (en) 2017-11-16
EP2909171A1 (fr) 2015-08-26
WO2014060366A1 (fr) 2014-04-24
FR2996847A1 (fr) 2014-04-18
AU2013331764A1 (en) 2015-05-21
US9546159B2 (en) 2017-01-17
EP2909171B1 (fr) 2016-09-28
US20150344460A1 (en) 2015-12-03

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20181012

FZDE Discontinued

Effective date: 20230822