CA2882705C - Nanoparticle formulation comprising cationic cholesterol derivatives for delivery of short-chain fatty acids - Google Patents
Nanoparticle formulation comprising cationic cholesterol derivatives for delivery of short-chain fatty acids Download PDFInfo
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- CA2882705C CA2882705C CA2882705A CA2882705A CA2882705C CA 2882705 C CA2882705 C CA 2882705C CA 2882705 A CA2882705 A CA 2882705A CA 2882705 A CA2882705 A CA 2882705A CA 2882705 C CA2882705 C CA 2882705C
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| MX387817B (es) | 2015-01-23 | 2025-03-11 | Univ Temple | Uso de acidos grasos de cadena corta en prevencion de cancer. |
| CN111759823B (zh) * | 2015-09-17 | 2022-12-30 | 阿赖耶识（上海）生物技术有限公司 | 一种高稳定的非囊泡型纳米颗粒及其在治疗微生物感染中的应用 |
| CN105669964B (zh) * | 2016-03-04 | 2017-11-21 | 博瑞生物医药（苏州）股份有限公司 | 卵巢癌特异靶向的生物可降解双亲性聚合物、由其制备的聚合物囊泡及应用 |
| US11065217B2 (en) | 2017-01-27 | 2021-07-20 | Temple University—Of the Commonwealth System of Higher Education | Use of short chain fatty acids for the treatment and prevention of diseases and disorders |
| US11077173B2 (en) | 2017-03-13 | 2021-08-03 | Sdg, Inc. | Lipid-based nanoparticles and methods using same |
| SG11201908052PA (en) | 2017-03-13 | 2019-09-27 | Sdg Inc | Lipid-based nanoparticles with enhanced stability |
| KR102665545B1 (ko) | 2017-04-17 | 2024-05-13 | 더 유니버서티 오브 시카고 | 인간 건강에의 적용 및 질환의 치료를 위한 장으로의 단쇄 지방산의 전달을 위한 중합체 재료 |
| CN107049954A (zh) * | 2017-06-12 | 2017-08-18 | 杭州普施康生物科技有限公司 | 一种药物组合及其制备方法和用途 |
| CN110192651A (zh) * | 2019-05-31 | 2019-09-03 | 浙江工业大学 | 一种利用大豆分离蛋白负载植物甾醇酯的纳米乳液的制备方法 |
| CN111426659B (zh) * | 2020-03-24 | 2023-06-06 | 深圳唯公生物科技有限公司 | 磁性荧光编码微球及其制备方法 |
| WO2023205810A2 (en) * | 2022-04-22 | 2023-10-26 | University Of Virginia Patent Foundation | Nano-enhanced vaccine |
| WO2024102902A1 (en) * | 2022-11-10 | 2024-05-16 | Temple University-Of The Commonwealth System Of Higher Education | Methods of treating or preventing liver diseases or disorders |
| CN118105524B (zh) * | 2024-03-14 | 2024-11-22 | 南京鼓楼医院 | 一种靶向肠上皮细胞的焦亡抑制剂药物递送系统及其制备方法和应用 |
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| US6756054B1 (en) * | 1996-05-24 | 2004-06-29 | Ic-Vec Limited | Polycationic sterol derivatives as transfection agents |
| US6146847A (en) * | 1996-11-01 | 2000-11-14 | Genespan Corporation | Stabilized transient gene expression |
| IT1303787B1 (it) * | 1998-11-25 | 2001-02-23 | Maria Rosa Gasco | "nanosfere lipidiche solide atte ad una rapida internalizzazione nellecellule" |
| JP2002532407A (ja) * | 1998-12-18 | 2002-10-02 | アルザ・コーポレーション | 多薬物耐性細胞に対する化合物の投与方法 |
| US6387952B1 (en) | 2000-09-19 | 2002-05-14 | Arco Chemical Technology L.P. | Method of treating gastrointestinal disorders, particularly colitis |
| WO2003030864A1 (en) * | 2001-05-29 | 2003-04-17 | Neopharm, Inc. | Liposomal formulation of irinotecan |
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| US20090123388A1 (en) | 2005-01-14 | 2009-05-14 | Medical College Of Georgia Research Institute | Prodrugs of Short-Chain Fatty Acids and Treatment Methods |
| WO2006127977A1 (en) * | 2005-05-24 | 2006-11-30 | The Johns Hopkins University | Fatty acid carbohydrate hybrid molecules as therapeutic agents and methods thereof |
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| US7700567B2 (en) | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
| WO2008078102A2 (en) * | 2006-12-22 | 2008-07-03 | Imuthes Limited | Lipids and their use as non-viral delivery vehicle |
| JP2012509258A (ja) * | 2008-11-17 | 2012-04-19 | エンゾン ファーマシューティカルズ，インコーポレーテッド | 核酸送達系のための分岐カチオン性脂質 |
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| GB201215289D0 (en) | 2012-10-10 |
| JP6483017B2 (ja) | 2019-03-13 |
| CN104837482A (zh) | 2015-08-12 |
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| WO2014033453A1 (en) | 2014-03-06 |
| EP2890365A1 (en) | 2015-07-08 |
| US10201499B2 (en) | 2019-02-12 |
| CN104837482B (zh) | 2018-09-18 |
| US20150224054A1 (en) | 2015-08-13 |
| HK1211862A1 (en) | 2016-06-03 |
| AU2013308245A1 (en) | 2015-04-09 |
| AU2013308245B2 (en) | 2018-03-29 |
| JP2015530382A (ja) | 2015-10-15 |
| EP2890365B1 (en) | 2019-11-20 |
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