CA2870198C - Process for purifying recombinant plasmodium falciparum circumsporozoite protein - Google Patents

Process for purifying recombinant plasmodium falciparum circumsporozoite protein Download PDF

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Publication number
CA2870198C
CA2870198C CA2870198A CA2870198A CA2870198C CA 2870198 C CA2870198 C CA 2870198C CA 2870198 A CA2870198 A CA 2870198A CA 2870198 A CA2870198 A CA 2870198A CA 2870198 C CA2870198 C CA 2870198C
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CA
Canada
Prior art keywords
rcsp
days
circumsporozoite protein
falciparum circumsporozoite
arginine
Prior art date
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Active
Application number
CA2870198A
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English (en)
French (fr)
Other versions
CA2870198A1 (en
Inventor
Jeffrey Allen
Greg CANTIN
Ryan HAVERSTOCK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pelican Technology Holdings Inc
Original Assignee
Pfenex Inc
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Publication of CA2870198A1 publication Critical patent/CA2870198A1/en
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Publication of CA2870198C publication Critical patent/CA2870198C/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2870198A 2012-05-01 2013-04-22 Process for purifying recombinant plasmodium falciparum circumsporozoite protein Active CA2870198C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261641105P 2012-05-01 2012-05-01
US61/641,105 2012-05-01
US13/844,261 US9169304B2 (en) 2012-05-01 2013-03-15 Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
US13/844,261 2013-03-15
PCT/US2013/037656 WO2013165732A1 (en) 2012-05-01 2013-04-22 Process for purifying recombinant plasmodium falciparum circumsporozoite protein

Publications (2)

Publication Number Publication Date
CA2870198A1 CA2870198A1 (en) 2013-11-07
CA2870198C true CA2870198C (en) 2019-12-03

Family

ID=49514758

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2870198A Active CA2870198C (en) 2012-05-01 2013-04-22 Process for purifying recombinant plasmodium falciparum circumsporozoite protein

Country Status (16)

Country Link
US (2) US9169304B2 (https=)
EP (1) EP2844666B1 (https=)
JP (1) JP6238967B2 (https=)
KR (1) KR102087461B1 (https=)
CN (1) CN104379596B (https=)
AR (1) AR090900A1 (https=)
AU (1) AU2013256757B2 (https=)
BR (1) BR112014027019B1 (https=)
CA (1) CA2870198C (https=)
MX (1) MX352093B (https=)
MY (1) MY166380A (https=)
NZ (1) NZ630121A (https=)
SG (1) SG11201407108TA (https=)
TW (1) TWI630213B (https=)
WO (1) WO2013165732A1 (https=)
ZA (1) ZA201407420B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
CA2971151C (en) * 2014-01-09 2020-10-27 Kentucky Bioprocessing, Inc. Method of purifying monoclonal antibodies
CN106459876A (zh) * 2014-03-28 2017-02-22 促接合因子股份有限公司 治疗性细菌的小菌落变异株的制备
CN107532190B (zh) 2014-12-01 2021-07-09 菲尼克斯公司 用于肽生产的融合伴侣
CN109966319B (zh) * 2017-12-22 2022-11-22 四川好医生攀西药业有限责任公司 一种康复新液的原料及其制备方法和应用
CN108559721A (zh) * 2018-05-15 2018-09-21 北京师范大学 一种净化空气的复合微生物菌剂及其应用
EP4171630A1 (en) * 2020-06-29 2023-05-03 Path Pre-erythrocytic malaria vaccines

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Also Published As

Publication number Publication date
KR102087461B1 (ko) 2020-03-10
AU2013256757B2 (en) 2017-02-16
BR112014027019A2 (pt) 2017-07-11
MX2014013124A (es) 2015-02-05
JP2015517464A (ja) 2015-06-22
EP2844666A4 (en) 2015-11-04
CN104379596B (zh) 2018-05-29
CA2870198A1 (en) 2013-11-07
US20140051841A1 (en) 2014-02-20
NZ630121A (en) 2016-06-24
SG11201407108TA (en) 2014-11-27
AU2013256757A1 (en) 2014-10-30
US9169304B2 (en) 2015-10-27
WO2013165732A1 (en) 2013-11-07
TWI630213B (zh) 2018-07-21
CN104379596A (zh) 2015-02-25
TW201348250A (zh) 2013-12-01
ZA201407420B (en) 2016-10-26
MX352093B (es) 2017-11-08
KR20150027743A (ko) 2015-03-12
JP6238967B2 (ja) 2017-11-29
EP2844666A1 (en) 2015-03-11
AR090900A1 (es) 2014-12-17
BR112014027019B1 (pt) 2022-09-06
US20160051677A1 (en) 2016-02-25
US9849177B2 (en) 2017-12-26
MY166380A (en) 2018-06-25
EP2844666B1 (en) 2019-07-17

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