CA2861982C - Composition from lobster hemocyte extract for detection of lipopolysaccharides, peptidoglycans and 1,3-.beta.-d-glucans. - Google Patents

Composition from lobster hemocyte extract for detection of lipopolysaccharides, peptidoglycans and 1,3-.beta.-d-glucans. Download PDF

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Publication number
CA2861982C
CA2861982C CA2861982A CA2861982A CA2861982C CA 2861982 C CA2861982 C CA 2861982C CA 2861982 A CA2861982 A CA 2861982A CA 2861982 A CA2861982 A CA 2861982A CA 2861982 C CA2861982 C CA 2861982C
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Prior art keywords
composition
hemocytes
lobster
lysate
propo
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CA2861982A
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English (en)
French (fr)
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CA2861982A1 (en
Inventor
Rolando PERDOMO MORALES
Vivian MONTERO ALEJO
Erick PERERA BRAVET
Jorge Ernesto CALERO CARBONELL
Zenia Pardo Ruiz
Marlene PORTO VERDECIA
Yamile VEGA HURTADO
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Universidad de la Habana
Centro de Investigacion y Desarrollo de Medicamentos CIDEM
Original Assignee
Universidad de la Habana
Centro de Investigacion y Desarrollo de Medicamentos CIDEM
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Publication of CA2861982A1 publication Critical patent/CA2861982A1/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CA2861982A 2011-12-27 2012-12-27 Composition from lobster hemocyte extract for detection of lipopolysaccharides, peptidoglycans and 1,3-.beta.-d-glucans. Active CA2861982C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CU20110243A CU24073B1 (es) 2011-12-27 2011-12-27 COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
CUCU/P/2011/0243 2011-12-27
PCT/CU2012/000009 WO2013113296A1 (es) 2011-12-27 2012-12-27 COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-β-ϋ-GLUCANOS.

Publications (2)

Publication Number Publication Date
CA2861982A1 CA2861982A1 (en) 2013-08-08
CA2861982C true CA2861982C (en) 2020-11-10

Family

ID=47632642

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2861982A Active CA2861982C (en) 2011-12-27 2012-12-27 Composition from lobster hemocyte extract for detection of lipopolysaccharides, peptidoglycans and 1,3-.beta.-d-glucans.

Country Status (10)

Country Link
US (2) US10023899B2 (enExample)
EP (1) EP2811031B8 (enExample)
JP (1) JP6341486B2 (enExample)
BR (1) BR112014016111B1 (enExample)
CA (1) CA2861982C (enExample)
CO (1) CO7101194A2 (enExample)
CU (1) CU24073B1 (enExample)
ES (1) ES2690565T3 (enExample)
IN (1) IN2014DN05849A (enExample)
WO (1) WO2013113296A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU24750B1 (es) 2020-11-19 2025-06-11 Centro De Investig Y Desarrollo De Medicamentos Cidem Entidades peptídicas con actividad antimicrobiana frente a patógenos multi-drogoresistentes

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* Cited by examiner, † Cited by third party
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US497052A (en) 1893-05-09 Eyelid-lifter
US547984A (en) 1895-10-15 Cutter-cylinder
US3954663A (en) 1972-12-18 1976-05-04 Teikoku Horinine Mfg. Co. Ltd. Process for the preparation of Limulina lysate
US4023802A (en) 1974-10-02 1977-05-17 Acushnet Company Golf club wood
US4107077A (en) 1975-07-14 1978-08-15 Associates Of Cape Cod, Inc. Limulus lysate of improved sensitivity and preparing the same
US4038029A (en) 1976-01-20 1977-07-26 Worthington Biochemical Corporation Limulus lysate turbidity test for pyrogens
JPS5415797A (en) 1977-06-14 1979-02-05 Seikagaku Kogyo Co Ltd Detection and measurement of toxin in cells
US4229541A (en) 1978-10-06 1980-10-21 Baxter Travenol Laboratories, Inc. In vitro cultivation of horseshoe crab amebocytes
US4279774A (en) 1979-11-13 1981-07-21 Dynasciences Corporation Method of removing lipid inhibitors from limulus amebocyte lysate
US4322217A (en) 1980-06-27 1982-03-30 Mallinckrodt, Inc. Process for preparing Limulus lysate
US4510241A (en) 1981-09-03 1985-04-09 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
ATE188777T1 (de) 1986-12-03 2000-01-15 Wako Pure Chem Ind Ltd Verfahren zum sammeln von insekten- körperflussigkeiten
JPH0715474B2 (ja) 1988-02-27 1995-02-22 和光純薬工業株式会社 エンドトキシンの測定法
JPH0711523B2 (ja) 1988-03-16 1995-02-08 和光純薬工業株式会社 試薬の調製方法
CA1328074C (en) 1988-09-01 1994-03-29 Shigenori Tanaka Horseshoe crab amebocyte lysate factor g inhibitor
US5082782A (en) 1988-12-27 1992-01-21 Worcester Polytechnic Institute Production of horseshoe crab amebocytes in vitro
ATE148230T1 (de) 1989-10-30 1997-02-15 Biowhittaker Inc Kinetische bestimmungsmethode für endotoxin unter verwendung von limulus-amoebocyten-lysat und chromogenem substrat
DE69129365T2 (de) 1990-08-22 1998-10-08 Seikagaku Kogyo K K Seikagaku Testagens für endotoxin
JP3122454B2 (ja) 1990-09-27 2001-01-09 生化学工業株式会社 カブトガニ・アメボサイト・ライセートの調製法
JP3429036B2 (ja) 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
DE69430038T2 (de) 1993-11-18 2002-10-24 Wako Pure Chemical Industries, Ltd. Verfahren zur Bestimmung der Aktivität des Prophenoloxidaseaktivierenden Enzyms und dessen Anwendung
US5716834A (en) 1994-08-19 1998-02-10 National University Of Singapore Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme
US6645724B1 (en) 1997-09-19 2003-11-11 National University Of Singapore Assays for endotoxin
US6270982B1 (en) 1997-10-09 2001-08-07 Charles River Laboratories Methods and compositions for the detection of bacterial endotoxins
EP0924220A3 (en) 1997-12-16 2000-04-26 Wako Pure Chemical Industries, Ltd. Inhibitor of the activation of beta-glucan recognition protein
US5998389A (en) 1998-05-20 1999-12-07 Biowhitaker Technologies Endotoxin-specific assay
JP3657913B2 (ja) 2000-01-20 2005-06-08 サムヤン ジェネックス コーポレイション β−1、3−グルカン検出用組成物、その製造方法及びそれを利用したβ−1、3−グルカン検出用キット
JP2005500520A (ja) 2001-06-28 2005-01-06 ケンブレックス バイオ サイエンス ウォカーズビル インコーポレーティッド エンドトキシンを検出するための方法および試薬
WO2003083090A1 (en) 2002-03-28 2003-10-09 Council Of Scientific And Industrial Research In vitro culture of amoebocytes from tachypleus gigas in leibovitz culture medium
US7598054B2 (en) 2003-10-31 2009-10-06 Immunetics, Inc. Rapid peptidoglycan-based assay for detection of bacterial contamination of platelets
EP3190185A1 (en) 2006-07-07 2017-07-12 Seikagaku Corporation Pro-clotting enzyme, and method for detection of endotoxin or (1-3)-beta-d-glucan using the same
EP2122632B1 (en) 2006-12-22 2014-06-25 Sidense Corp. Dual function data register

Also Published As

Publication number Publication date
EP2811031B8 (en) 2018-12-26
BR112014016111B1 (pt) 2020-11-24
CU20110243A7 (es) 2013-08-29
CA2861982A1 (en) 2013-08-08
ES2690565T3 (es) 2018-11-21
US20140356889A1 (en) 2014-12-04
BR112014016111A8 (pt) 2020-10-27
IN2014DN05849A (enExample) 2015-05-22
CO7101194A2 (es) 2014-10-31
EP2811031B1 (en) 2018-07-11
WO2013113296A1 (es) 2013-08-08
US10023899B2 (en) 2018-07-17
US20180340206A1 (en) 2018-11-29
JP6341486B2 (ja) 2018-06-13
BR112014016111A2 (pt) 2018-05-22
US10844421B2 (en) 2020-11-24
JP2015506679A (ja) 2015-03-05
EP2811031A1 (en) 2014-12-10
CU24073B1 (es) 2015-01-29

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