CU20110243A7 - COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS - Google Patents

COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS

Info

Publication number
CU20110243A7
CU20110243A7 CU2011000243A CU20110243A CU20110243A7 CU 20110243 A7 CU20110243 A7 CU 20110243A7 CU 2011000243 A CU2011000243 A CU 2011000243A CU 20110243 A CU20110243 A CU 20110243A CU 20110243 A7 CU20110243 A7 CU 20110243A7
Authority
CU
Cuba
Prior art keywords
composition
extract
peptidoglicanos
lipopolisacáridos
hemocits
Prior art date
Application number
CU2011000243A
Other languages
English (en)
Other versions
CU24073B1 (es
Inventor
Morales Rolando Perdomo
Alejo Vivian Montero
Bravet Erick Perera
Carbonell Jorge Ernesto Calero
Ruiz Zenia Pardo
Verdecia Marlene Porto
Hurtado Yamile Vega
Original Assignee
Ct De Investigación Y Desarrollo De Medicamentos Cidem
Ct De Investigaciones Marinas Cim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct De Investigación Y Desarrollo De Medicamentos Cidem, Ct De Investigaciones Marinas Cim filed Critical Ct De Investigación Y Desarrollo De Medicamentos Cidem
Priority to CU20110243A priority Critical patent/CU24073B1/es
Priority to CA2861982A priority patent/CA2861982C/en
Priority to US14/368,697 priority patent/US10023899B2/en
Priority to IN5849DEN2014 priority patent/IN2014DN05849A/en
Priority to PCT/CU2012/000009 priority patent/WO2013113296A1/es
Priority to BR112014016111-9A priority patent/BR112014016111B1/pt
Priority to EP12821102.6A priority patent/EP2811031B8/en
Priority to ES12821102.6T priority patent/ES2690565T3/es
Priority to JP2014549358A priority patent/JP6341486B2/ja
Publication of CU20110243A7 publication Critical patent/CU20110243A7/es
Priority to CO14162207A priority patent/CO7101194A2/es
Publication of CU24073B1 publication Critical patent/CU24073B1/es
Priority to US16/012,975 priority patent/US10844421B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invención se relaciona con la farmacéutica, la química y la biotecnología, y en particular con un proceso para preparar una composición para detectar y medir la concentración de endotoxinas o lipopolisacáridos, peptidoglicanos y (1,3)-ß-D-glucanos empleando un extracto de los hemocitos de las langostas como material de partida, las modificaciones a la composición para incrementar su sensibilidad, así como los procesos para medir endotoxinas, peptidoglicanos y (1,3)-ß-D-glucanos empleando dicha composición.
CU20110243A 2011-12-27 2011-12-27 COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS CU24073B1 (es)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CU20110243A CU24073B1 (es) 2011-12-27 2011-12-27 COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
BR112014016111-9A BR112014016111B1 (pt) 2011-12-27 2012-12-27 Processos para obter uma composiçao, e para detectar lipopolissacarideos, peptidoglicanos e 1,3-ss-d-glucanos
US14/368,697 US10023899B2 (en) 2011-12-27 2012-12-27 Composition from lobster hemocyte extracts for detection of lipopolysaccharides, peptidoglycans and 1,3-beta-D-glucans
IN5849DEN2014 IN2014DN05849A (es) 2011-12-27 2012-12-27
PCT/CU2012/000009 WO2013113296A1 (es) 2011-12-27 2012-12-27 COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-β-ϋ-GLUCANOS.
CA2861982A CA2861982C (en) 2011-12-27 2012-12-27 Composition from lobster hemocyte extract for detection of lipopolysaccharides, peptidoglycans and 1,3-.beta.-d-glucans.
EP12821102.6A EP2811031B8 (en) 2011-12-27 2012-12-27 Composition from lobster hemocyte extract for detection of lipopolysaccharides, peptidoglycans and 1,3-beta-d-glucans
ES12821102.6T ES2690565T3 (es) 2011-12-27 2012-12-27 Composición a partir de extracto de hemocitos de langosta para la detección de lipopolisacáridos, peptidoglicanos y 1 ,3-ß-d-glucanos
JP2014549358A JP6341486B2 (ja) 2011-12-27 2012-12-27 リポ多糖、ペプチドグリカン及び１，３−β−Ｄ−グルカンを検出するためのロブスター血球抽出物からの組成物
CO14162207A CO7101194A2 (es) 2011-12-27 2014-07-25 Composicion a partir de extracto de hemocitos de langosta para la deteccion de lipopolisacaridos, peptidoglicanos y 1,3-beta-d-glucanos
US16/012,975 US10844421B2 (en) 2011-12-27 2018-06-20 Composition from lobster hemocyte extracts for detection of lipopolysaccharides, peptidoglycans and 1,3-beta-D-glucans

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20110243A CU24073B1 (es) 2011-12-27 2011-12-27 COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS

Publications (2)

Publication Number Publication Date
CU20110243A7 true CU20110243A7 (es) 2013-08-29
CU24073B1 CU24073B1 (es) 2015-01-29

Family

ID=47632642

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20110243A CU24073B1 (es) 2011-12-27 2011-12-27 COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS

Country Status (10)

Country Link
US (2) US10023899B2 (es)
EP (1) EP2811031B8 (es)
JP (1) JP6341486B2 (es)
BR (1) BR112014016111B1 (es)
CA (1) CA2861982C (es)
CO (1) CO7101194A2 (es)
CU (1) CU24073B1 (es)
ES (1) ES2690565T3 (es)
IN (1) IN2014DN05849A (es)
WO (1) WO2013113296A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU20200086A7 (es) 2020-11-19 2022-06-06 Centro De Investig Y Desarrollo De Medicamentos Cidem Entidades peptídicas con actividad antimicrobiana frente a patógenos multi-drogoresistentes

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US547984A (en) 1895-10-15 Cutter-cylinder
US497052A (en) 1893-05-09 Eyelid-lifter
US3954663A (en) 1972-12-18 1976-05-04 Teikoku Horinine Mfg. Co. Ltd. Process for the preparation of Limulina lysate
US4023802A (en) 1974-10-02 1977-05-17 Acushnet Company Golf club wood
US4107077A (en) 1975-07-14 1978-08-15 Associates Of Cape Cod, Inc. Limulus lysate of improved sensitivity and preparing the same
US4038029A (en) 1976-01-20 1977-07-26 Worthington Biochemical Corporation Limulus lysate turbidity test for pyrogens
JPS5415797A (en) 1977-06-14 1979-02-05 Seikagaku Kogyo Co Ltd Detection and measurement of toxin in cells
US4229541A (en) 1978-10-06 1980-10-21 Baxter Travenol Laboratories, Inc. In vitro cultivation of horseshoe crab amebocytes
US4279774A (en) 1979-11-13 1981-07-21 Dynasciences Corporation Method of removing lipid inhibitors from limulus amebocyte lysate
US4322217A (en) 1980-06-27 1982-03-30 Mallinckrodt, Inc. Process for preparing Limulus lysate
US4510241A (en) 1981-09-03 1985-04-09 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
EP0634656B1 (en) * 1986-12-03 2000-01-12 Wako Pure Chemical Industries, Ltd. Processes for collecting body fluid from insects
JPH0715474B2 (ja) 1988-02-27 1995-02-22 和光純薬工業株式会社 エンドトキシンの測定法
JPH0711523B2 (ja) 1988-03-16 1995-02-08 和光純薬工業株式会社 試薬の調製方法
CA1328074C (en) 1988-09-01 1994-03-29 Shigenori Tanaka Horseshoe crab amebocyte lysate factor g inhibitor
US5082782A (en) 1988-12-27 1992-01-21 Worcester Polytechnic Institute Production of horseshoe crab amebocytes in vitro
ATE148230T1 (de) 1989-10-30 1997-02-15 Biowhittaker Inc Kinetische bestimmungsmethode für endotoxin unter verwendung von limulus-amoebocyten-lysat und chromogenem substrat
DE69129365T2 (de) 1990-08-22 1998-10-08 Seikagaku Kogyo K K Seikagaku Testagens für endotoxin
JP3122454B2 (ja) 1990-09-27 2001-01-09 生化学工業株式会社 カブトガニ・アメボサイト・ライセートの調製法
JP3429036B2 (ja) 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
DE69430038T2 (de) 1993-11-18 2002-10-24 Wako Pure Chem Ind Ltd Verfahren zur Bestimmung der Aktivität des Prophenoloxidaseaktivierenden Enzyms und dessen Anwendung
US5716834A (en) 1994-08-19 1998-02-10 National University Of Singapore Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme
US6645724B1 (en) 1997-09-19 2003-11-11 National University Of Singapore Assays for endotoxin
US6270982B1 (en) 1997-10-09 2001-08-07 Charles River Laboratories Methods and compositions for the detection of bacterial endotoxins
EP0924220A3 (en) 1997-12-16 2000-04-26 Wako Pure Chemical Industries, Ltd. Inhibitor of the activation of beta-glucan recognition protein
US5998389A (en) 1998-05-20 1999-12-07 Biowhitaker Technologies Endotoxin-specific assay
JP3195582B2 (ja) * 1998-08-05 2001-08-06 セイコーインスツルメンツ株式会社 記録装置のアクチュエータ
AU2891401A (en) 2000-01-20 2001-07-31 Samyang Genex Corporation Composition for detecting beta-1,3-glucan, preparation method thereof and diagnostic kit detecting beta-1,3-glucan
US20040235080A1 (en) 2001-06-28 2004-11-25 Lin Chen Methods and reagents for detecting endotoxin
WO2003083090A1 (en) 2002-03-28 2003-10-09 Council Of Scientific And Industrial Research In vitro culture of amoebocytes from tachypleus gigas in leibovitz culture medium
US7598054B2 (en) * 2003-10-31 2009-10-06 Immunetics, Inc. Rapid peptidoglycan-based assay for detection of bacterial contamination of platelets
CN103060349A (zh) 2006-07-07 2013-04-24 生化学工业株式会社 凝固酶原以及使用所述酶检测内毒素或(1→3)-β-D-葡聚糖的方法
WO2008077243A1 (en) 2006-12-22 2008-07-03 Sidense Corp. A power up detection system for a memory device

Also Published As

Publication number Publication date
JP2015506679A (ja) 2015-03-05
EP2811031B1 (en) 2018-07-11
EP2811031B8 (en) 2018-12-26
BR112014016111A2 (pt) 2018-05-22
BR112014016111B1 (pt) 2020-11-24
ES2690565T3 (es) 2018-11-21
EP2811031A1 (en) 2014-12-10
WO2013113296A1 (es) 2013-08-08
CO7101194A2 (es) 2014-10-31
US10844421B2 (en) 2020-11-24
US20140356889A1 (en) 2014-12-04
JP6341486B2 (ja) 2018-06-13
CA2861982A1 (en) 2013-08-08
CU24073B1 (es) 2015-01-29
US20180340206A1 (en) 2018-11-29
US10023899B2 (en) 2018-07-17
CA2861982C (en) 2020-11-10
BR112014016111A8 (pt) 2020-10-27
IN2014DN05849A (es) 2015-05-22

Similar Documents

Publication Publication Date Title
MX2019015016A (es) Ensayos para la deteccion de una sola molecula y uso de los mismos.
CY1119200T1 (el) Νεα παραγωγα βενζιμιδαζολιου ως ερ4 ανταγωνιστες
EA201590027A1 (ru) Способы детекции заболеваний или состояний
MX366275B (es) Metodos para detectar y medir la agregacion.
AR091098A1 (es) ANTICUERPOS E INMUNOCONJUGADOS CONTRA Ly6E Y METODOS DE USO
BR112012024312A2 (pt) anticorpos biespecíficos
CL2013000322A1 (es) Compuestos derivados de piperidina sustituida; proceso de preparacion; composicion farmaceutica y su uso para producir un efecto antiproliferativo y/o proapoptotico.
BR112014013082A2 (pt) método para detectar adutos nucleossomos
SMT201600231B (it) Metodo per misurare la concentrazione di alcool nel respiro e relativo apparecchio
SMT201400145B (it) Metodo per la rivelazione di anticorpi aBeta-specifici in un campione biologico
CY1121304T1 (el) Μεθοδος καθαρισμου σαπωνινων
BR112012033591A2 (pt) processo de detecção de interações moleculares.
CY1122360T1 (el) Μεθοδος για τη διαγνωση της νοσου niemann-pick
CL2017001043A1 (es) Detección de malaria.
EA201591742A1 (ru) Способ улучшения диагностики заболеваний с использованием измеряемых аналитов
GB2509682A (en) Biomarkers useful for detection of tyres, grades and stages of human breast cancer
PE20170815A1 (es) Metodo y aparato para el proceso de flotacion por espuma utilizando mediciones opticas
BR112014032916A2 (pt) anticorpos anti-fármacos e usos destes para o monitoramento de fármaco
BR112014029808A2 (pt) método para testar o efeito de uma etapa de produção ou etapas de produção ou a eficácia de uma etapa de purificação ou etapas de purificação na presença ou na natureza de moléculas pró-inflamatórias em polímeros de glicose ou hidrolisados dos mesmos; e método otimizado para produzir ou purificar polímeros de glicose ou hidrolisados dos mesmos
MY181007A (en) Scale drop disease (sdd) causative virus and derivatives thereof
BR112013017683A2 (pt) método de medir a concentração de um analito em uma solução aquosa
CU20110243A7 (es) COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
EA201400356A1 (ru) Иммуноанализ для обнаружения антибиотиков
SG10201907690TA (en) Device and method for detecting target molecules
CY1121482T1 (el) Ευαισθητη πολυπλεκτικη ανοσοδοκιμασια για τους διαλυτους υποδοχεις των αυξητικων παραγοντων των ινοβλαστων

Legal Events

Date Code Title Description
FG Grant of patent