CA2859689C - Methods for treating gout in patient subpopulations - Google Patents

Methods for treating gout in patient subpopulations Download PDF

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Publication number
CA2859689C
CA2859689C CA2859689A CA2859689A CA2859689C CA 2859689 C CA2859689 C CA 2859689C CA 2859689 A CA2859689 A CA 2859689A CA 2859689 A CA2859689 A CA 2859689A CA 2859689 C CA2859689 C CA 2859689C
Authority
CA
Canada
Prior art keywords
compound
gout
subject
uric acid
halofenate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2859689A
Other languages
English (en)
French (fr)
Other versions
CA2859689A1 (en
Inventor
Gopal Chandra SAHA
Brian K. Roberts
Brian Edward LAVAN
Charles A. Mcwherter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diatex Inc
CymaBay Therapeutics Inc
Original Assignee
Diatex Inc
CymaBay Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diatex Inc, CymaBay Therapeutics Inc filed Critical Diatex Inc
Publication of CA2859689A1 publication Critical patent/CA2859689A1/en
Application granted granted Critical
Publication of CA2859689C publication Critical patent/CA2859689C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2859689A 2011-11-04 2011-11-04 Methods for treating gout in patient subpopulations Expired - Fee Related CA2859689C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/059425 WO2013066352A1 (en) 2011-11-04 2011-11-04 Methods for treating gout in patient subpopulations

Publications (2)

Publication Number Publication Date
CA2859689A1 CA2859689A1 (en) 2013-05-10
CA2859689C true CA2859689C (en) 2018-05-22

Family

ID=48192536

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2859689A Expired - Fee Related CA2859689C (en) 2011-11-04 2011-11-04 Methods for treating gout in patient subpopulations

Country Status (14)

Country Link
EP (1) EP2775835A4 (enrdf_load_stackoverflow)
JP (1) JP6047172B2 (enrdf_load_stackoverflow)
KR (1) KR101848122B1 (enrdf_load_stackoverflow)
CN (1) CN104066323A (enrdf_load_stackoverflow)
AU (1) AU2011380509B2 (enrdf_load_stackoverflow)
BR (1) BR112014010693A2 (enrdf_load_stackoverflow)
CA (1) CA2859689C (enrdf_load_stackoverflow)
CL (1) CL2014001156A1 (enrdf_load_stackoverflow)
IL (1) IL232385A (enrdf_load_stackoverflow)
MX (1) MX354846B (enrdf_load_stackoverflow)
NZ (1) NZ624714A (enrdf_load_stackoverflow)
SG (1) SG11201402027PA (enrdf_load_stackoverflow)
WO (1) WO2013066352A1 (enrdf_load_stackoverflow)
ZA (1) ZA201403574B (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104602686A (zh) * 2012-04-13 2015-05-06 西玛贝医药公司 利用卤芬酯或卤芬酸以及抗炎剂治疗痛风患者中高尿酸血症的方法
CN105851522A (zh) * 2014-07-25 2016-08-17 许伟琦 一种防止尿路结石的饲料
CN105920022A (zh) * 2016-05-12 2016-09-07 成都易创思生物科技有限公司 一种抗痛风药物复方制剂
WO2019082335A1 (ja) * 2017-10-26 2019-05-02 大塚製薬株式会社 イノシトールリン酸含有組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250191A (en) * 1978-11-30 1981-02-10 Edwards K David Preventing renal failure
US6262118B1 (en) * 1999-06-04 2001-07-17 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
CN102643241B (zh) * 2007-11-27 2015-01-21 亚德生化公司 化合物和组合物以及使用方法

Also Published As

Publication number Publication date
CL2014001156A1 (es) 2015-01-16
KR20140123927A (ko) 2014-10-23
KR101848122B1 (ko) 2018-04-11
IL232385A0 (en) 2014-06-30
MX2014005399A (es) 2015-04-08
CA2859689A1 (en) 2013-05-10
NZ624714A (en) 2016-01-29
WO2013066352A1 (en) 2013-05-10
EP2775835A4 (en) 2015-07-29
JP2014532759A (ja) 2014-12-08
MX354846B (es) 2018-03-22
BR112014010693A2 (pt) 2020-11-10
SG11201402027PA (en) 2014-09-26
EP2775835A1 (en) 2014-09-17
CN104066323A (zh) 2014-09-24
JP6047172B2 (ja) 2016-12-21
AU2011380509B2 (en) 2016-05-19
ZA201403574B (en) 2015-11-25
AU2011380509A1 (en) 2014-05-29
IL232385A (en) 2017-10-31

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CA2859693C (en) Methods for treating gout flares
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CA2859686C (en) Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second urate-lowering agent
CA2859689C (en) Methods for treating gout in patient subpopulations
AU2013245675B2 (en) Method for treating hyperuricemia in patients with gout using halofenate or halofenic acid and an anti-inflammatory agent
JP6368756B2 (ja) ハロフェナートまたはハロフェン酸および第2の尿酸低下薬を用いる痛風に罹っている患者の高尿酸血症の治療方法
US20130302305A1 (en) Methods for Treating Gout in Patients Subpopulations
JP6192142B2 (ja) 痛風発赤の治療方法

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20161028

MKLA Lapsed

Effective date: 20210831

MKLA Lapsed

Effective date: 20191104