EP2775835A4 - Methods for treating gout in patient subpopulations - Google Patents

Methods for treating gout in patient subpopulations

Info

Publication number
EP2775835A4
EP2775835A4 EP11875027.2A EP11875027A EP2775835A4 EP 2775835 A4 EP2775835 A4 EP 2775835A4 EP 11875027 A EP11875027 A EP 11875027A EP 2775835 A4 EP2775835 A4 EP 2775835A4
Authority
EP
European Patent Office
Prior art keywords
methods
treating gout
patient subpopulations
subpopulations
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11875027.2A
Other languages
German (de)
French (fr)
Other versions
EP2775835A1 (en
Inventor
Gopal Chandra Saha
Brian K Roberts
Brian Edward Lavan
Charles A Mcwherter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diatex Inc
CymaBay Therapeutics Inc
Original Assignee
Metabolex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolex Inc filed Critical Metabolex Inc
Publication of EP2775835A1 publication Critical patent/EP2775835A1/en
Publication of EP2775835A4 publication Critical patent/EP2775835A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP11875027.2A 2011-11-04 2011-11-04 Methods for treating gout in patient subpopulations Withdrawn EP2775835A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/059425 WO2013066352A1 (en) 2011-11-04 2011-11-04 Methods for treating gout in patient subpopulations

Publications (2)

Publication Number Publication Date
EP2775835A1 EP2775835A1 (en) 2014-09-17
EP2775835A4 true EP2775835A4 (en) 2015-07-29

Family

ID=48192536

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11875027.2A Withdrawn EP2775835A4 (en) 2011-11-04 2011-11-04 Methods for treating gout in patient subpopulations

Country Status (14)

Country Link
EP (1) EP2775835A4 (en)
JP (1) JP6047172B2 (en)
KR (1) KR101848122B1 (en)
CN (1) CN104066323A (en)
AU (1) AU2011380509B2 (en)
BR (1) BR112014010693A2 (en)
CA (1) CA2859689C (en)
CL (1) CL2014001156A1 (en)
IL (1) IL232385A (en)
MX (1) MX354846B (en)
NZ (1) NZ624714A (en)
SG (1) SG11201402027PA (en)
WO (1) WO2013066352A1 (en)
ZA (1) ZA201403574B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150002799A (en) * 2012-04-13 2015-01-07 사이머베이 쎄라퓨틱스, 인코퍼레이티드 Method for treating hyperuricemia in patients with gout using halofenate or halofenic acid and an anti-inflammatory agent
CN104068288B (en) * 2014-07-25 2016-08-24 许伟琦 A kind of feed additive of anti-lithangiuria
CN105920022A (en) * 2016-05-12 2016-09-07 成都易创思生物科技有限公司 Anti-gout medicinal compound preparation
JP7086980B2 (en) * 2017-10-26 2022-06-20 大塚製薬株式会社 Inositol phosphate-containing composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250191A (en) * 1978-11-30 1981-02-10 Edwards K David Preventing renal failure
US6262118B1 (en) * 1999-06-04 2001-07-17 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI415840B (en) * 2007-11-27 2013-11-21 Ardea Biosciences Inc Novel compounds and compositions and methods of use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250191A (en) * 1978-11-30 1981-02-10 Edwards K David Preventing renal failure
US6262118B1 (en) * 1999-06-04 2001-07-17 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
US6613802B1 (en) * 1999-06-04 2003-09-02 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Metabolex Appoints Raymond Urbanski M.D., Ph.D. to Position of Chief Medical Officer", 20 October 2011 (2011-10-20), XP002740530, Retrieved from the Internet <URL:http://www.fiercebiotech.com> [retrieved on 20150603] *
ANONYMOUS: "Metabolex Initiates Phase 2 Trial of Arhalofenate", 19 May 2011 (2011-05-19), XP002740529, Retrieved from the Internet <URL:http://www.prnewswire.com/news-releases> [retrieved on 20150603] *
EDWARDS K D G ET AL: "AMINO NUCLEOSIDE INDUCED CHRONIC RENAL FAILURE IN RATS ENHANCEMENT BY DIETARY HYPER LIPIDEMIAS AND PROTECTION BY A HYPO LIPIDEMIC DIET OR HALOFENATE", KIDNEY INTERNATIONAL, vol. 14, no. 6, 1978, pages 723, XP002740532, ISSN: 0085-2538 *
EDWARDS K D G ET AL: "PROTECTION BY L TRYPTOPHAN OR HALOFENATE AGAINST HYPER LIPIDEMIA AND ACUTE OR CHRONIC AMINO NUCLEOSIDE NEPHROSIS IN SUCROSE LARD FED RATS", KIDNEY INTERNATIONAL, vol. 12, no. 6, 1977, pages 480, XP002740533, ISSN: 0085-2538 *
EL-ZAWAWY HOSSAM ET AL: "Managing gout: How is it different in patients with chronic kidney disease?", CLEVELAND CLINIC JOURNAL OF MEDICINE, vol. 77, no. 12, December 2010 (2010-12-01), pages 919 - 928, XP002740531 *
MAHESH J FULDEORE ET AL: "Chronic kidney disease in gout in a managed care setting", BMC NEPHROLOGY, BIOMED CENTRAL, LONDON, GB, vol. 12, no. 1, 3 August 2011 (2011-08-03), pages 36, XP021108842, ISSN: 1471-2369, DOI: 10.1186/1471-2369-12-36 *
See also references of WO2013066352A1 *

Also Published As

Publication number Publication date
KR101848122B1 (en) 2018-04-11
MX2014005399A (en) 2015-04-08
BR112014010693A2 (en) 2020-11-10
NZ624714A (en) 2016-01-29
SG11201402027PA (en) 2014-09-26
CA2859689C (en) 2018-05-22
ZA201403574B (en) 2015-11-25
CA2859689A1 (en) 2013-05-10
EP2775835A1 (en) 2014-09-17
MX354846B (en) 2018-03-22
IL232385A (en) 2017-10-31
IL232385A0 (en) 2014-06-30
WO2013066352A1 (en) 2013-05-10
JP6047172B2 (en) 2016-12-21
KR20140123927A (en) 2014-10-23
AU2011380509B2 (en) 2016-05-19
CN104066323A (en) 2014-09-24
JP2014532759A (en) 2014-12-08
CL2014001156A1 (en) 2015-01-16
AU2011380509A1 (en) 2014-05-29

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20140522

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAX Request for extension of the european patent (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: A01N 37/00 20060101ALI20150609BHEP

Ipc: A61P 19/06 20060101ALI20150609BHEP

Ipc: A61K 31/20 20060101AFI20150609BHEP

RA4 Supplementary search report drawn up and despatched (corrected)

Effective date: 20150626

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CYMABAY THERAPEUTICS, INC.

17Q First examination report despatched

Effective date: 20170331

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CYMABAY THERAPEUTICS, INC.

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: DIATEX, INC.

Owner name: CYMABAY THERAPEUTICS, INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20190205