CA2854054C - Amphipathic lipid-based sustained release compositions - Google Patents
Amphipathic lipid-based sustained release compositions Download PDFInfo
- Publication number
- CA2854054C CA2854054C CA2854054A CA2854054A CA2854054C CA 2854054 C CA2854054 C CA 2854054C CA 2854054 A CA2854054 A CA 2854054A CA 2854054 A CA2854054 A CA 2854054A CA 2854054 C CA2854054 C CA 2854054C
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- composition
- sustained release
- composition according
- active ingredient
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Classifications
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- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
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- Immunology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
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| US201161566279P | 2011-12-02 | 2011-12-02 | |
| US61/566,279 | 2011-12-02 | ||
| PCT/US2012/067361 WO2013082470A1 (en) | 2011-12-02 | 2012-11-30 | Amphipathic lipid-based sustained release compositions |
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| CA2854054A1 CA2854054A1 (en) | 2013-06-06 |
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| US (1) | US9248096B2 (enExample) |
| EP (1) | EP2785333A4 (enExample) |
| JP (1) | JP2015500241A (enExample) |
| AU (1) | AU2012345726B2 (enExample) |
| BR (1) | BR112014013175B1 (enExample) |
| CA (1) | CA2854054C (enExample) |
| MX (1) | MX351453B (enExample) |
| WO (1) | WO2013082470A1 (enExample) |
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| CA2807552A1 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| EP3431485B2 (en) | 2010-10-01 | 2024-09-04 | ModernaTX, Inc. | Engineered nucleic acids and methods of use thereof |
| WO2012135805A2 (en) | 2011-03-31 | 2012-10-04 | modeRNA Therapeutics | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| EP2763701B1 (en) | 2011-10-03 | 2018-12-19 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
| KR20140102759A (ko) | 2011-12-16 | 2014-08-22 | 모더나 세라퓨틱스, 인코포레이티드 | 변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물 |
| DE18200782T1 (de) | 2012-04-02 | 2021-10-21 | Modernatx, Inc. | Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| CA2892529C (en) | 2012-11-26 | 2023-04-25 | Moderna Therapeutics, Inc. | Terminally modified rna |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| EP3041934A1 (en) | 2013-09-03 | 2016-07-13 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
| US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| EA201690675A1 (ru) | 2013-10-03 | 2016-08-31 | Модерна Терапьютикс, Инк. | Полинуклеотиды, кодирующие рецептор липопротеинов низкой плотности |
| US11564893B2 (en) | 2015-08-17 | 2023-01-31 | Modernatx, Inc. | Methods for preparing particles and related compositions |
| EP3349735A4 (en) * | 2015-09-16 | 2019-05-15 | Corr-Jensen Inc. | MULTI-PHASE RELEASE OF SPORTING NUTRITION AND ENERGY BEVERAGE COMPOSITIONS THROUGH LIPID PARTICLES |
| DK3350157T3 (da) | 2015-09-17 | 2022-02-14 | Modernatx Inc | Forbindelser og sammensætninger til intracellulær afgivelse af terapeutiske midler |
| MD3386484T2 (ro) | 2015-12-10 | 2022-11-30 | Modernatx Inc | Compoziții și metode de livrare a unor agenți terapeutici |
| AU2016377681B2 (en) | 2015-12-22 | 2021-05-13 | Modernatx, Inc. | Compounds and compositions for intracellular delivery of agents |
| US11583504B2 (en) | 2016-11-08 | 2023-02-21 | Modernatx, Inc. | Stabilized formulations of lipid nanoparticles |
| CA3055653A1 (en) | 2017-03-15 | 2018-09-20 | Modernatx, Inc. | Lipid nanoparticle formulation |
| AU2018234692B2 (en) | 2017-03-15 | 2022-06-02 | Modernatx, Inc. | Compounds and compositions for intracellular delivery of therapeutic agents |
| ES2911186T3 (es) | 2017-03-15 | 2022-05-18 | Modernatx Inc | Formas cristalinas de aminolípidos |
| WO2018232120A1 (en) | 2017-06-14 | 2018-12-20 | Modernatx, Inc. | Compounds and compositions for intracellular delivery of agents |
| US20190110988A1 (en) * | 2017-10-17 | 2019-04-18 | Lemulsa Technologies Inc. | Delivery System That Utilizes Liposomal or Emulsion Vehicles |
| US12263248B2 (en) | 2018-09-19 | 2025-04-01 | Modernatx, Inc. | Compounds and compositions for intracellular delivery of therapeutic agents |
| EP4509118A3 (en) | 2018-09-19 | 2025-05-14 | ModernaTX, Inc. | High-purity peg lipids and uses thereof |
| CA3113025A1 (en) | 2018-09-19 | 2020-03-26 | Modernatx, Inc. | Peg lipids and uses thereof |
| AU2019386979B2 (en) | 2018-11-26 | 2023-03-16 | The Procter & Gamble Company | Solid pharmaceutical preparation containing lipoic acid and use thereof |
| CA3154618A1 (en) | 2019-09-19 | 2021-03-25 | Modernatx, Inc. | Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents |
| US11524023B2 (en) | 2021-02-19 | 2022-12-13 | Modernatx, Inc. | Lipid nanoparticle compositions and methods of formulating the same |
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| JPS6348226A (ja) * | 1986-08-14 | 1988-02-29 | Ono Pharmaceut Co Ltd | 徐放性を有する経口投与用固形製剤 |
| US5993850A (en) | 1994-09-13 | 1999-11-30 | Skyepharma Inc. | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
| US6077534A (en) * | 1997-09-02 | 2000-06-20 | Klinge Pharma Gmbh | Production of pharmaceutical formulations for treatment of edema and venous disorders |
| DE19740983A1 (de) * | 1997-09-18 | 1999-04-08 | Warner Lambert Co N D Ges D St | Verfahren zur Erschwerung der Extraktion von Wirkstoffen aus Tabletten |
| AU747549B2 (en) | 1998-03-23 | 2002-05-16 | General Mills Inc. | Encapsulation of components into edible products |
| DK1183014T3 (da) | 1999-06-14 | 2004-02-09 | Cosmo Spa | Smagsmaskerede orale farmaceutiske sammensætninger med kontrolleret frigivelse |
| US7314640B2 (en) * | 2003-07-11 | 2008-01-01 | Mongkol Sriwongjanya | Formulation and process for drug loaded cores |
| PL204079B1 (pl) * | 2004-08-12 | 2009-12-31 | Inst Farmaceutyczny | Stały doustny preparat chlorowodorku tamsulozyny o przedłużonym uwalnianiu i sposób jego wytwarzania |
| ES2350029T3 (es) | 2007-03-02 | 2011-01-17 | Farnam Companies, Inc. | Pellets de liberación sostenida que comprenden un material tipo cera. |
| US8404275B2 (en) * | 2007-07-01 | 2013-03-26 | Vitalis Llc | Combination tablet with chewable outer layer |
| JP5608653B2 (ja) | 2008-09-04 | 2014-10-15 | ファーナム・カンパニーズ・インコーポレーテッド | チュアブルな徐放性製剤 |
| EP2435029B1 (en) * | 2009-05-28 | 2016-12-14 | KRKA, tovarna zdravil, d.d., Novo mesto | Pharmaceutical composition comprising tamsulosin |
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| MX351453B (es) | 2017-10-16 |
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| CA2854054A1 (en) | 2013-06-06 |
| WO2013082470A1 (en) | 2013-06-06 |
| BR112014013175A8 (pt) | 2021-06-08 |
| AU2012345726B2 (en) | 2017-04-13 |
| BR112014013175B1 (pt) | 2022-08-09 |
| EP2785333A4 (en) | 2015-04-01 |
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Effective date: 20171128 |