CA2853966C - Multisomes: encapsulated droplet networks - Google Patents

Multisomes: encapsulated droplet networks Download PDF

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Publication number
CA2853966C
CA2853966C CA2853966A CA2853966A CA2853966C CA 2853966 C CA2853966 C CA 2853966C CA 2853966 A CA2853966 A CA 2853966A CA 2853966 A CA2853966 A CA 2853966A CA 2853966 C CA2853966 C CA 2853966C
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CA
Canada
Prior art keywords
droplet
aqueous
bilayer
amphipathic molecules
droplets
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Active
Application number
CA2853966A
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English (en)
French (fr)
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CA2853966A1 (en
Inventor
John Hagan Pryce Bayley
Andrew Heron
Gabriel VILLAR
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Oxford University Innovation Ltd
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Oxford University Innovation Ltd
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Publication of CA2853966A1 publication Critical patent/CA2853966A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/025—Applications of microcapsules not provided for in other subclasses
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0097—Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
CA2853966A 2011-11-03 2012-11-02 Multisomes: encapsulated droplet networks Active CA2853966C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1119032.9A GB201119032D0 (en) 2011-11-03 2011-11-03 Multisomes: encapsulated droplet networks
GB1119032.9 2011-11-03
US201261592062P 2012-01-30 2012-01-30
US61/592,062 2012-01-30
PCT/GB2012/052736 WO2013064837A1 (en) 2011-11-03 2012-11-02 Multisomes: encapsulated droplet networks

Publications (2)

Publication Number Publication Date
CA2853966A1 CA2853966A1 (en) 2013-05-10
CA2853966C true CA2853966C (en) 2021-07-06

Family

ID=45375781

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2853966A Active CA2853966C (en) 2011-11-03 2012-11-02 Multisomes: encapsulated droplet networks

Country Status (11)

Country Link
US (3) US10548852B2 (https=)
EP (1) EP2773451A1 (https=)
JP (1) JP6234371B2 (https=)
KR (1) KR102038450B1 (https=)
CN (1) CN104053497B (https=)
AU (1) AU2012330894B2 (https=)
BR (1) BR112014010811B1 (https=)
CA (1) CA2853966C (https=)
GB (1) GB201119032D0 (https=)
IN (1) IN2014CN03680A (https=)
WO (1) WO2013064837A1 (https=)

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KR20220159986A (ko) * 2020-03-26 2022-12-05 고쿠리쓰다이가쿠호진 규슈다이가쿠 이온 액체, 용매, 제제 및 경피흡수제
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Also Published As

Publication number Publication date
US11998642B2 (en) 2024-06-04
WO2013064837A1 (en) 2013-05-10
US20200214988A1 (en) 2020-07-09
JP2015501328A (ja) 2015-01-15
US20140356289A1 (en) 2014-12-04
BR112014010811A2 (pt) 2017-05-02
CN104053497B (zh) 2017-04-26
JP6234371B2 (ja) 2017-11-22
EP2773451A1 (en) 2014-09-10
IN2014CN03680A (https=) 2015-09-25
CN104053497A (zh) 2014-09-17
AU2012330894B2 (en) 2017-07-13
US20230048266A1 (en) 2023-02-16
KR102038450B1 (ko) 2019-11-26
CA2853966A1 (en) 2013-05-10
BR112014010811B1 (pt) 2022-07-12
US11406603B2 (en) 2022-08-09
US10548852B2 (en) 2020-02-04
BR112014010811A8 (pt) 2018-01-02
AU2012330894A1 (en) 2014-05-29
KR20140097303A (ko) 2014-08-06
GB201119032D0 (en) 2011-12-14

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