CA2853711C - A liquid enzyme formulation and a process for its preparation - Google Patents

A liquid enzyme formulation and a process for its preparation Download PDF

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Publication number
CA2853711C
CA2853711C CA2853711A CA2853711A CA2853711C CA 2853711 C CA2853711 C CA 2853711C CA 2853711 A CA2853711 A CA 2853711A CA 2853711 A CA2853711 A CA 2853711A CA 2853711 C CA2853711 C CA 2853711C
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Canada
Prior art keywords
transglutaminase
formulation
polyol
enzyme
suspension
Prior art date
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CA2853711A
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English (en)
French (fr)
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CA2853711A1 (en
Inventor
Kirsi Rajakari
Kai Hotakainen
Paivi Myllarinen
Original Assignee
Valio Oy
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0059—Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0061—Laccase (1.10.3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03001—Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03002—Laccase (1.10.3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/02—Aminoacyltransferases (2.3.2)
    • C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01043—Peptidyl-glutaminase (3.5.1.43)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
CA2853711A 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation Active CA2853711C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20116074A FI126442B (en) 2011-11-01 2011-11-01 Liquid enzyme preparation and process for its preparation
FI20116074 2011-11-01
PCT/FI2012/051048 WO2013064736A1 (en) 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation

Publications (2)

Publication Number Publication Date
CA2853711A1 CA2853711A1 (en) 2013-05-10
CA2853711C true CA2853711C (en) 2019-11-26

Family

ID=47215584

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2853711A Active CA2853711C (en) 2011-11-01 2012-10-31 A liquid enzyme formulation and a process for its preparation

Country Status (19)

Country Link
US (1) US20140287098A1 (enExample)
EP (1) EP2773753B1 (enExample)
JP (1) JP6297979B2 (enExample)
KR (1) KR101998182B1 (enExample)
CN (2) CN104024406A (enExample)
AU (1) AU2012331034B2 (enExample)
BR (1) BR112014010222B1 (enExample)
CA (1) CA2853711C (enExample)
CL (1) CL2014001100A1 (enExample)
DK (1) DK2773753T3 (enExample)
ES (1) ES2697675T3 (enExample)
FI (1) FI126442B (enExample)
IL (1) IL232356B (enExample)
IN (1) IN2014MN00968A (enExample)
MX (1) MX356454B (enExample)
PL (1) PL2773753T3 (enExample)
RU (1) RU2668396C2 (enExample)
WO (1) WO2013064736A1 (enExample)
ZA (1) ZA201403965B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6341091B2 (ja) 2012-10-17 2018-06-13 味の素株式会社 化粧料組成物
CN107177567B (zh) * 2016-02-16 2018-07-03 上海青瑞食品科技有限公司 一种液体酶制剂及制备方法
KR102512028B1 (ko) 2016-04-01 2023-03-20 오틀리 아베 증가된 점도의 귀리 베이스 및 발효된 귀리 베이스 제품
CN105852053A (zh) * 2016-04-20 2016-08-17 上海青瑞食品科技有限公司 一种液体酶制剂在食品质构改良中的应用
JP6787563B2 (ja) * 2016-06-30 2020-11-18 千葉製粉株式会社 接着成形食品の製造方法、接着成形食品用の接着成分分散液、および、接着成形食品
CN107897533A (zh) * 2017-12-10 2018-04-13 济南诺能生物工程有限公司 一种单胃动物液体复合酶的制备方法
JP7501357B2 (ja) 2018-03-23 2024-06-18 味の素株式会社 トランスグルタミナーゼを含有する液体製剤
CN122278976A (zh) * 2020-03-17 2026-06-26 天野酶制品株式会社 蛋白质的交联方法
EP4150062A4 (en) * 2020-05-13 2024-08-14 Curie Co. Inc. TRANSGLUTAMINASE VARIANTS AND METHODS OF USE THEREOF
CN116057184A (zh) * 2020-09-10 2023-05-02 天野酶制品株式会社 加工蛋白质的制造方法
US20230329292A1 (en) * 2020-09-10 2023-10-19 Amano Enzyme Inc. Tofu production method
JP7829496B2 (ja) * 2020-12-04 2026-03-13 天野エンザイム株式会社 液体酵素製剤
EP4414450A4 (en) * 2021-10-04 2025-07-02 Amano Enzyme Inc LIQUID TRANSGLUTAMINASE ENZYME PREPARATION
WO2023228953A1 (ja) * 2022-05-23 2023-11-30 天野エンザイム株式会社 液体酵素製剤
CN115380981A (zh) * 2022-08-09 2022-11-25 武汉新华扬生物股份有限公司 一种用于冷萃咖啡的复配酶制剂及其应用方法
EP4428218A1 (en) * 2023-03-07 2024-09-11 SkyLab AG Biodegradable transglutaminase-based detergent composition for regeneration of microdamage and regulation of elasticity of delicate fiber
AU2024303157A1 (en) 2023-06-14 2026-01-08 Amano Enzyme Inc. Liquid enzyme preparation
CN121620590A (zh) 2023-09-01 2026-03-06 诺维信公司 稳定的液体脱酰胺酶组合物
EP4777622A1 (en) * 2023-09-13 2026-07-22 Novozymes A/S Stabilized deamidase compositions
WO2025233391A1 (en) * 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
EP4650443A1 (en) 2024-05-13 2025-11-19 Novozymes A/S Stabilized liquid deamidase compositions

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665280B2 (ja) 1987-03-04 1994-08-24 味の素株式会社 タンパクゲル化剤及びそれを用いるタンパクのゲル化方法
US5340734A (en) * 1992-11-25 1994-08-23 Biosource Genetics Corporation Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
FI955962L (fi) * 1994-04-18 1995-12-13 Gist Brocades Bv Stabiilit vesi-öljyemulsiot
EP0777726B1 (en) 1994-08-26 2006-06-07 Novozymes A/S Microbial transglutaminases, their production and use
CN1167791C (zh) * 1997-03-12 2004-09-22 诺沃奇梅兹有限公司 包含漆酶的耐贮存液体制剂
DE60125805T2 (de) * 2000-09-28 2007-10-11 Dsm Ip Assets B.V. Flüssige brotverbesserungsmittel
US20030219853A1 (en) * 2002-03-01 2003-11-27 Szu-Yi Chou Method of cross-linking a compound
CN100448366C (zh) * 2002-09-26 2009-01-07 味之素株式会社 酶制剂及用其生产食品的方法
JP2005034078A (ja) * 2003-07-17 2005-02-10 Rengo Co Ltd タンパク質安定化剤
EP1836897A1 (en) * 2006-03-22 2007-09-26 Nestec S.A. A solid product comprising oil-droplets
GB2438287A (en) * 2006-05-19 2007-11-21 Norbrook Lab Ltd Stable aqueous suspension
CN101945995B (zh) * 2008-02-13 2013-06-12 天野酶株式会社 稳定型转谷氨酰胺酶及其制造法
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Also Published As

Publication number Publication date
CL2014001100A1 (es) 2014-09-05
CN104024406A (zh) 2014-09-03
JP6297979B2 (ja) 2018-03-20
DK2773753T3 (en) 2018-12-10
ZA201403965B (en) 2015-05-27
ES2697675T3 (es) 2019-01-25
RU2668396C2 (ru) 2018-09-28
AU2012331034B2 (en) 2017-10-19
IL232356B (en) 2019-03-31
WO2013064736A1 (en) 2013-05-10
KR101998182B1 (ko) 2019-10-01
KR20140096090A (ko) 2014-08-04
RU2014121318A (ru) 2015-12-10
MX356454B (es) 2018-05-30
BR112014010222B1 (pt) 2022-04-12
BR112014010222A8 (pt) 2017-06-20
EP2773753B1 (en) 2018-10-17
IL232356A0 (en) 2014-06-30
PL2773753T3 (pl) 2019-03-29
CA2853711A1 (en) 2013-05-10
FI20116074L (fi) 2013-05-02
US20140287098A1 (en) 2014-09-25
FI126442B (en) 2016-12-15
MX2014005128A (es) 2014-07-09
EP2773753A1 (en) 2014-09-10
CN108676782A (zh) 2018-10-19
IN2014MN00968A (enExample) 2015-04-24
JP2014532421A (ja) 2014-12-08
AU2012331034A1 (en) 2014-06-26
BR112014010222A2 (pt) 2017-06-13

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