CA2852855C - Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof - Google Patents

Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof Download PDF

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Publication number
CA2852855C
CA2852855C CA2852855A CA2852855A CA2852855C CA 2852855 C CA2852855 C CA 2852855C CA 2852855 A CA2852855 A CA 2852855A CA 2852855 A CA2852855 A CA 2852855A CA 2852855 C CA2852855 C CA 2852855C
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Prior art keywords
snp
nucleic acid
snps
protein
allele
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Expired - Lifetime
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CA2852855A
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English (en)
French (fr)
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CA2852855A1 (en
Inventor
Michele Cargill
Hongjin Huang
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Celera Corp
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Celera Corp
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Priority to CA2887830A priority Critical patent/CA2887830C/en
Priority claimed from CA2837792A external-priority patent/CA2837792C/en
Publication of CA2852855A1 publication Critical patent/CA2852855A1/en
Application granted granted Critical
Publication of CA2852855C publication Critical patent/CA2852855C/en
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2852855A 2004-05-07 2005-05-09 Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof Expired - Lifetime CA2852855C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2887830A CA2887830C (en) 2004-05-07 2005-05-09 Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US56884604P 2004-05-07 2004-05-07
US60/568,846 2004-05-07
US58260904P 2004-06-25 2004-06-25
US60/582,609 2004-06-25
US59955404P 2004-08-09 2004-08-09
US60/599,554 2004-08-09
CA2837792A CA2837792C (en) 2004-05-07 2005-05-09 Genetic polymorphism in lrp5 associated with liver fibrosis methods of detection and uses thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2837792A Division CA2837792C (en) 2004-05-07 2005-05-09 Genetic polymorphism in lrp5 associated with liver fibrosis methods of detection and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2887830A Division CA2887830C (en) 2004-05-07 2005-05-09 Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof

Publications (2)

Publication Number Publication Date
CA2852855A1 CA2852855A1 (en) 2005-11-24
CA2852855C true CA2852855C (en) 2016-07-05

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Family Applications (2)

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CA2852855A Expired - Lifetime CA2852855C (en) 2004-05-07 2005-05-09 Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof
CA2566256A Expired - Lifetime CA2566256C (en) 2004-05-07 2005-05-09 Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof

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CA2566256A Expired - Lifetime CA2566256C (en) 2004-05-07 2005-05-09 Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof

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US (7) US7820380B2 (OSRAM)
EP (5) EP2412826B1 (OSRAM)
JP (8) JP5236286B2 (OSRAM)
CA (2) CA2852855C (OSRAM)
WO (1) WO2005111241A2 (OSRAM)

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Also Published As

Publication number Publication date
EP1745154B1 (en) 2012-08-01
CA2566256A1 (en) 2005-11-24
WO2005111241A3 (en) 2006-06-01
US20210025000A1 (en) 2021-01-28
JP5236286B2 (ja) 2013-07-17
US20140072957A1 (en) 2014-03-13
US8071302B2 (en) 2011-12-06
EP2423326A3 (en) 2012-06-13
JP2018023392A (ja) 2018-02-15
EP2412826A3 (en) 2012-05-02
JP2016005480A (ja) 2016-01-14
CA2852855A1 (en) 2005-11-24
JP5733844B2 (ja) 2015-06-10
US20110129831A1 (en) 2011-06-02
US7820380B2 (en) 2010-10-26
EP2423326A2 (en) 2012-02-29
US20160032388A1 (en) 2016-02-04
WO2005111241A8 (en) 2006-12-28
JP2011142914A (ja) 2011-07-28
JP2009523005A (ja) 2009-06-18
EP2412827B1 (en) 2014-01-22
JP2016027815A (ja) 2016-02-25
US20190127796A1 (en) 2019-05-02
EP1745154A2 (en) 2007-01-24
EP2423327A2 (en) 2012-02-29
CA2566256C (en) 2015-07-07
EP2423326B1 (en) 2014-01-08
US20060024700A1 (en) 2006-02-02
JP6448149B2 (ja) 2019-01-09
EP2412827A3 (en) 2012-05-16
WO2005111241A2 (en) 2005-11-24
US20120276528A1 (en) 2012-11-01
JP6124968B2 (ja) 2017-05-10
US10718023B2 (en) 2020-07-21
JP2013233150A (ja) 2013-11-21
JP2014027931A (ja) 2014-02-13
EP2412827A2 (en) 2012-02-01
JP2018023391A (ja) 2018-02-15
EP2423327A3 (en) 2012-05-23
EP2412826B1 (en) 2014-01-08
EP2423327B1 (en) 2014-01-08
EP2412826A2 (en) 2012-02-01

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