CA2841152C - Procede de detection d'anomalies lors du remplissage d'un dispositif de dosage de liquide et dispositif de dosage de liquide - Google Patents
Procede de detection d'anomalies lors du remplissage d'un dispositif de dosage de liquide et dispositif de dosage de liquide Download PDFInfo
- Publication number
- CA2841152C CA2841152C CA2841152A CA2841152A CA2841152C CA 2841152 C CA2841152 C CA 2841152C CA 2841152 A CA2841152 A CA 2841152A CA 2841152 A CA2841152 A CA 2841152A CA 2841152 C CA2841152 C CA 2841152C
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- CA
- Canada
- Prior art keywords
- filling
- pressure
- liquid
- curves
- curve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000007788 liquid Substances 0.000 title claims abstract description 140
- 238000000034 method Methods 0.000 title claims abstract description 82
- 238000001514 detection method Methods 0.000 claims abstract description 31
- 238000004364 calculation method Methods 0.000 claims description 37
- 230000002123 temporal effect Effects 0.000 claims description 18
- 210000000056 organ Anatomy 0.000 claims description 14
- 238000004891 communication Methods 0.000 claims description 6
- 238000003556 assay Methods 0.000 claims description 4
- 238000013213 extrapolation Methods 0.000 description 11
- 238000005259 measurement Methods 0.000 description 8
- 238000012545 processing Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000007423 decrease Effects 0.000 description 3
- 230000006978 adaptation Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 101100086436 Caenorhabditis elegans rap-1 gene Proteins 0.000 description 1
- 241000416536 Euproctis pseudoconspersa Species 0.000 description 1
- 108010071289 Factor XIII Proteins 0.000 description 1
- 101100518987 Mus musculus Pax1 gene Proteins 0.000 description 1
- 101100420081 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) rps-0 gene Proteins 0.000 description 1
- LUNBMBVWKORSGN-TYEKWLQESA-N P-factor Chemical compound CC(C)C[C@@H](C(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=2C3=CC=CC=C3NC=2)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)O)C(C)C)CCC1 LUNBMBVWKORSGN-TYEKWLQESA-N 0.000 description 1
- 101800002502 P-factor Proteins 0.000 description 1
- 102100038374 Pinin Human genes 0.000 description 1
- 101710173952 Pinin Proteins 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000008186 active pharmaceutical agent Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 230000009194 climbing Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000009432 framing Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 238000007562 laser obscuration time method Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67D—DISPENSING, DELIVERING OR TRANSFERRING LIQUIDS, NOT OTHERWISE PROVIDED FOR
- B67D7/00—Apparatus or devices for transferring liquids from bulk storage containers or reservoirs into vehicles or into portable containers, e.g. for retail sale purposes
- B67D7/06—Details or accessories
- B67D7/08—Arrangements of devices for controlling, indicating, metering or registering quantity or price of liquid transferred
- B67D7/16—Arrangements of liquid meters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
- B01L3/0227—Details of motor drive means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
- G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
- G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
- G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
- G01F11/023—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type with provision for varying the stroke of the piston
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
- G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
- G01F11/021—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type
- G01F11/029—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the piston type provided with electric controlling means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
- B01L2200/146—Employing pressure sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/148—Specific details about calibrations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Mechanical Engineering (AREA)
- Analytical Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Measurement Of Levels Of Liquids Or Fluent Solid Materials (AREA)
- Details Of Flowmeters (AREA)
- Sampling And Sample Adjustment (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Basic Packing Technique (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1155747 | 2011-06-28 | ||
| FR1155747A FR2977317B1 (fr) | 2011-06-28 | 2011-06-28 | Procede de detection d'anomalies lors du remplissage d'un dispositif de dosage de liquide et dispositif de dosage de liquide |
| PCT/EP2012/061258 WO2013000716A1 (fr) | 2011-06-28 | 2012-06-14 | Procede de detection d'anomalies lors du remplissage d'un dispositif de dosage de liquide et dispositif de dosage de liquide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2841152A1 CA2841152A1 (fr) | 2013-01-03 |
| CA2841152C true CA2841152C (fr) | 2018-07-24 |
Family
ID=46420088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2841152A Active CA2841152C (fr) | 2011-06-28 | 2012-06-14 | Procede de detection d'anomalies lors du remplissage d'un dispositif de dosage de liquide et dispositif de dosage de liquide |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9751747B2 (enExample) |
| EP (1) | EP2726206B1 (enExample) |
| JP (1) | JP6278407B2 (enExample) |
| KR (1) | KR101943128B1 (enExample) |
| CN (1) | CN103619480B (enExample) |
| BR (1) | BR112013033294A2 (enExample) |
| CA (1) | CA2841152C (enExample) |
| ES (1) | ES2544105T3 (enExample) |
| FR (1) | FR2977317B1 (enExample) |
| PL (1) | PL2726206T3 (enExample) |
| WO (1) | WO2013000716A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103551215B (zh) * | 2013-10-10 | 2015-05-27 | 广州安必平自动化检测设备有限公司 | 一种移液装置及移液方法 |
| CA2957420A1 (en) | 2014-08-15 | 2016-02-18 | Biomerieux, Inc. | Methods, systems, and computer program products for verifying dispensing of a fluid from a pipette |
| FR3057182B1 (fr) * | 2016-10-10 | 2021-07-09 | Gilson Sas | Pipettes monocanal ou multicanal a actionnement manuel et bouton de commande destine a equiper de telles pipettes |
| US10859592B2 (en) * | 2017-01-31 | 2020-12-08 | Tecan Trading Ag | Method of aspirating by pipetting and pipetting apparatus |
| EP3434373A1 (de) | 2017-07-27 | 2019-01-30 | Eppendorf AG | Pipettiervorrichtung mit funktionsprüfung und verfahren zur funktionsprüfung einer pipettiervorrichtung |
| CN108061590A (zh) * | 2018-01-29 | 2018-05-22 | 淮阴工学院 | 气压式吸液探测器 |
| EP4104931B1 (de) * | 2021-06-18 | 2023-12-27 | Euroimmun Medizinische Labordiagnostika AG | Verfahren zur detektion eines fehlerzustandes beim aspirieren einer flüssigkeit |
| CN118500819B (zh) * | 2024-04-30 | 2025-08-08 | 深圳普门科技股份有限公司 | 吸样补偿参数的确定方法及装置、吸样设备 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2095152C (en) * | 1990-11-09 | 2003-02-18 | Charles W. Brentz | Sample pipetting method |
| FI90207C (fi) | 1992-05-04 | 1994-01-10 | Wallac Oy | Pipettilaitteisto |
| US5540081A (en) * | 1993-08-31 | 1996-07-30 | Abbott Laboratories | Pipetting apparatus with clot detection |
| JPH1048220A (ja) * | 1996-08-08 | 1998-02-20 | Hitachi Ltd | 分注装置 |
| US6022747A (en) * | 1998-07-10 | 2000-02-08 | Bayer Corporation | Blood clot detector |
| JP2000121649A (ja) * | 1998-10-09 | 2000-04-28 | Furuno Electric Co Ltd | 自動分注装置 |
| JP4328531B2 (ja) * | 2001-03-09 | 2009-09-09 | ハミルトン・ボナドゥーツ・アーゲー | 液体の所定量分配過程の評価方法及びその装置 |
| EP1812163B1 (en) * | 2004-10-11 | 2009-09-23 | Thermo Fisher Scientific Oy | Method for checking the condition of a sample when metering liquid |
| DE202006010293U1 (de) * | 2005-07-22 | 2006-08-31 | Tecan Trading Ag | Pipettiergerät mit Computerprogrammprodukt zum Akzeptieren oder Verwerfen von pipettierten Flüssigkeitsproben |
| DE102005060862B3 (de) * | 2005-12-20 | 2007-06-28 | Stratec Biomedical Systems Ag | Verfahren und Vorrichtung zur Beurteilung eines Dosiervorgangs |
| FR2895920B1 (fr) * | 2006-01-06 | 2008-04-18 | Gilson Sas Soc Par Actions Sim | Pipette multivolumes. |
| EP2009449A1 (en) * | 2007-06-06 | 2008-12-31 | Hamilton Bonaduz AG | Method of controlling a pipetting process |
| FR2917648B1 (fr) * | 2007-06-25 | 2009-09-25 | Gilson Sas Soc Par Actions Sim | Pipette permettant un prelevement de liquide par mouvement de va-et-vient du piston. |
| EP2031403B1 (en) * | 2007-08-27 | 2016-02-17 | Roche Diagnostics GmbH | Method for monitoring a fluid transfer process |
| US20090093065A1 (en) * | 2007-09-10 | 2009-04-09 | Zhong Ding | Aspirating and dispensing small volumes of liquids |
| US7867769B2 (en) * | 2007-09-19 | 2011-01-11 | Siemens Healthcare Diagnostics Inc. | Clog detection in a clinical sampling pipette |
| FR2927999B1 (fr) * | 2008-02-21 | 2010-09-17 | Gilson Sas | Viscosimetre comprenant un systeme de pipetage, a precision amelioree et conception simplifiee |
| EP2302397A1 (en) * | 2009-09-25 | 2011-03-30 | bioMérieux S.A. | Method, computer program, and apparatus for detecting pipetting errors |
-
2011
- 2011-06-28 FR FR1155747A patent/FR2977317B1/fr not_active Expired - Fee Related
-
2012
- 2012-06-14 US US14/126,918 patent/US9751747B2/en active Active
- 2012-06-14 KR KR1020137031917A patent/KR101943128B1/ko not_active Expired - Fee Related
- 2012-06-14 ES ES12730844.3T patent/ES2544105T3/es active Active
- 2012-06-14 CA CA2841152A patent/CA2841152C/fr active Active
- 2012-06-14 JP JP2014517573A patent/JP6278407B2/ja active Active
- 2012-06-14 PL PL12730844T patent/PL2726206T3/pl unknown
- 2012-06-14 WO PCT/EP2012/061258 patent/WO2013000716A1/fr not_active Ceased
- 2012-06-14 CN CN201280032096.9A patent/CN103619480B/zh active Active
- 2012-06-14 EP EP12730844.3A patent/EP2726206B1/fr active Active
- 2012-06-14 BR BR112013033294A patent/BR112013033294A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US9751747B2 (en) | 2017-09-05 |
| EP2726206A1 (fr) | 2014-05-07 |
| KR20140056177A (ko) | 2014-05-09 |
| KR101943128B1 (ko) | 2019-01-28 |
| PL2726206T3 (pl) | 2015-10-30 |
| WO2013000716A1 (fr) | 2013-01-03 |
| US20140137980A1 (en) | 2014-05-22 |
| EP2726206B1 (fr) | 2015-04-29 |
| CN103619480A (zh) | 2014-03-05 |
| BR112013033294A2 (pt) | 2017-03-01 |
| ES2544105T3 (es) | 2015-08-27 |
| JP2014528058A (ja) | 2014-10-23 |
| FR2977317B1 (fr) | 2013-08-02 |
| CN103619480B (zh) | 2015-09-30 |
| JP6278407B2 (ja) | 2018-02-14 |
| FR2977317A1 (fr) | 2013-01-04 |
| CA2841152A1 (fr) | 2013-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20170426 |